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排序方式: 共有481条查询结果,搜索用时 15 毫秒
41.
Hirofumi Hirayama Toshihiro Itoh Yoshihiko Nakaki Takahiko Yoshida 《Artificial Life and Robotics》2005,9(3):144-160
A mathematical method is introduced to characterize the electrokinetic behavior (electrophoresis) of a biomolecular particle which passes through a specific channel pore on an excitable biological membrane. The basic approach was first proposed by Booth (1950). The system was described by an equation of continuity and an equation of motion in which the driving force involves the diffusion effect, the hydrostatic pressure, and the electrostatic potential. By assuming linear relations between the velocity and the applied electrical field, solutions for the potential, pressure, and velocity were given by a series expansion of the charges on the particle. To examine the influence of ions surrounding the particle and forming an ionic cloud, the Debye–Huckel parameter was introduced. As the thickness of the double layer around the particle increased, the potential, velocity, pressure, and viscosity were changed significantly. The maximum influence was obtained when the radius of the particle became equal to the thickness of the double layer. Although this theory is valid for a charged, spherical, nonconducting particle only, the method is available for evaluating the kinetic behavior of a biomolecule that passes through a channel pore on a cellular membrane.This work was presented, in part, at the 8th International Symposium on Artificial Life and Robotics, Oita, Japan, January 24–26, 2003 相似文献
42.
Generalized Partial Computation (GPC) is a program transformation method utilizing partial information about input data, abstract
data types of auxiliary functions and the logical structure of a source program. GPC uses both an inference engine such as
a theorem prover and a classical partial evaluator to optimize programs. Therefore, GPC is more powerful than classical partial
evaluators but harder to implement and control. We have implemented an experimental GPC system called WSDFU (Waseda Simplify-Distribute-Fold-Unfold).
This paper demonstrates the power of the program transformation system as well as its theorem prover and discusses some future
works.
Yoshihiko Futamura, Ph.D.: He is Professor of Department of Information and Computer Science and the director of the Institute for Software Production
Technology (ISPT) of Waseda University. He received his BS in mathematics from Hokkaido University in 1965, MS in applied
mathematics from Harvard University in 1972 and Ph.D. degree from Hokkaido University in 1985. He joined Hitachi Central Research
Laboratory in 1965 and moved to Waseda University in 1991. He was a visiting professor of Uppsala University from 1985 to
1986 and a visiting scholar of Harvard University from 1988 to 1989. Automatic generation of computer programs and programming
methodology are his main research fields. He is the inventor of the Futamura Projections in partial evaluation and ISO8631
PAD (Problem Analysis Diagram).
Zenjiro Konishi: He is a visiting lecturer of Institute for Software Production Technology, Waseda University. He received his M. Sc. degree
in mathematics from Waseda University in 1995. His research interests include automated theorem proving. He received JSSST
Takahashi Award in 2001. He is a member of JSSST and IPSJ.
Robert Glück, Ph.D., Habil.: He is an Associate Professor of Computer Science at the University of Copenhagen. He received his Ph.D. and Habilitation
(venia docendi) from the Vienna University of Technology in 1991 and 1997. He was research assistant at the City University of New York
and received twice the Erwin-Schrodinger-Fellowship of the Austrian Science Foundation (FWF). After being an Invited Fellow
of the Japan Society for the Promotion of Science (JSPS), he is now funded by the PRESTO21 program for basic research of the
Japan Science and Technology Corporation (JST) and located at Waseda University in Tokyo. His main research interests are
advanced programming languages, theory and practice of program transformation, and metaprogramming. 相似文献
43.
Yamaguchi A Uejo F Yoda T Uchida T Tanamura Y Yamashita T Teramae N 《Nature materials》2004,3(5):337-341
A mesoporous membrane composed of nanochannels with a uniform diameter has a potential use for precise size-exclusive separation of molecules. Here, we report a novel method to form a hybrid membrane composed of silica-surfactant nanocomposite and a porous alumina membrane, by which size-selective transport of molecules across the membrane becomes possible. The nanocomposite formed inside each columnar alumina pore was an assembly of surfactant-templated silica-nanochannels with a channel diameter of 3.4 nm; the channel direction being predominantly oriented along the wall of the columnar alumina pore. Molecules could be transported across the membrane including the silica-surfactant nanocomposite with a capability of nanometre-order size-exclusive separation. Our proposed membrane system has a potential use not only for separation science, but also catalysis and chip technologies. 相似文献
44.
Shigeyuki Nagata Kengo Fukuzawa Yukio Iwashita Akira Kabashima Tadahiko Kinoshita Kenzo Wakasugi Yoshihiko Maehara 《Nutrition journal》2009,8(1):24-8
Background
Many clinical studies have demonstrated that early postoperative enteral nutrition (EN) improved the postroperative course. Post-pancreaticoduodenectomy (PD), patients tend to suffer from postoperative nausea, abdominal distention, and diarrhoea, causing difficulty in the introduction of EN. In this pilot study, we investigated the appropriate nutritional mode post-pancreatic surgery. 相似文献45.
Keiji Tsukada Mitsuteru Yoshioka Yoshihiko Kawasaki Toshihiko Kiwa 《NDT & E International》2010,43(4):323-328
We have developed a magnetic flux leakage (MFL) system using magnetic resistive (MR) sensors for detecting two dimensional magnetic field components, and an induction coil that generates low magnetic field strengths and extremely low frequencies. The signal at each scanned measurement point (i) was divided by the signal strength Mmes,i and phase αi by a lock-in amplifier. Using the strength Mmes,i and phase αi, we calculated the imaginary part of the signal using the common phase β. By optimization of the common phase β to the imaginary part, the analyzed scanning data curve was shown to be effective in estimating the size (depth and diameter) of back-side pits on a ferrous plate. Comparing the two dimensional magnetic field components of leakage, the imaginary part of the y-component parallel to the induced magnetic field was found to be suitable for detecting the back-side pits. 相似文献
46.
Kihara Ken; Yagi Yoshihiko; Takeda Yuji; Kawahara Jun I. 《Canadian Metallurgical Quarterly》2011,37(1):168
When two targets (T1 and T2) are embedded in rapid serial visual presentation (RSVP), T2 is often missed (attentional blink, AB) if T2 follows T1 by less than 500 ms. Some have proposed that inhibition of a distractor following T1 contributes to the AB, but no direct evidence supports this proposal. This study examined distractor inhibition by assessing a distractor devaluation effect where inhibited items were evaluated less positively than controls. Experiments 1 and 2 showed that a distractor presented just after T1 was evaluated less favorably when T2 was misidentified, independently of stimulus characteristics. Experiment 3 produced distractor devaluation in T2 incorrect trials when the evaluated distractor was the second item after T1. In contrast, a distractor presented before T1 was not devaluated (Experiment 4). Experiment 5 demonstrated that participants could not recognize presented distractors after an RSVP task, rejecting the possibility that memorized distractors were devalued. Results show a relationship between the devaluation of distractors following T1 and the AB, providing the first direct evidence of the distractor inhibition during the AB. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
47.
Crystallization behaviours around the glass transition temperature in an amorphous Fe70Nb10B20 alloy were investigated by means of transmission electron microscopy. Dense bcc-Fe nanocrystals initially appeared as the primary phase, followed by the dense formation of the (Fe,Nb)23B6 nanocrystalline phase. The bcc-Fe nanocrystals were formed even by annealing at a temperature that is 38 K lower than the glass transition temperature. A difference of the low temperature behaviours between the present conventional amorphous alloy and a bulk metallic glass was discussed. 相似文献
48.
The Feasibility Study on Commercialized Fast Reactor (FR) Cycle Systems is under progress in order to propose prominent FR cycle systems that will respond to the diverse needs of society in the future. The design studies on various FR system concepts have been achieved and then the evaluations of potential to achieve the development targets have been also carried out. Crucial development issues have been found out for each FR system concept and their development plans for the key technologies are summarized as the roadmap. As a result, it has been confirmed that the sodium-cooled FR concept is highly suited to the development targets and R&D issues are related enhancing the economy with certain perspectives for realization. A flexible and robust development program for the FR cycle system will be proposed taking account of the characteristics for each FR concept until the end of the Phase II study. 相似文献
49.
Yoshihiko Nakata Satoshi Ninomiya Chikage Imada Masafumi Nagai Takaaki Aoki Jiro Matsuo Nobutsugu Imanishi 《Nuclear instruments & methods in physics research. Section B, Beam interactions with materials and atoms》2005,230(1-4):489-494
We have measured both secondary neutral and ionized particles from an InSb target under 3.0 MeV Si ion bombardment. Measurements of both ions and neutrals have not been carried out so far in the MeV-energy range. The mass spectra and axial emission energy distributions of secondary particles were investigated. Secondary ions were measured with a linear- and a reflective-type time-of-flight technique, whereas secondary neutral particles were photo-ionized by a UV pulsed laser (ArF: 193 nm) and measured with a reflective-type time-of-flight technique. Different results were obtained for neutral particles in comparison with ionized particles. The mean energy of neutral Sb atoms was much lower than that of neutral In atoms, whereas the mean energies of secondary In and Sb ions were nearly equal. 相似文献
50.
The effect of small dose of topiroxostat on serum uric acid in patients receiving hemodialysis 下载免费PDF全文
Yume Nagaoka Yoshiko Tanaka Hiroshi Yoshimoto Rie Suzuki Kakei Ryu Mio Ueda Minako Akiyama Miho Nagai Yoshitaka Miyaoka Eiichiro Kanda Shinnichi Iwai Michio Nagaoka Yoshihiko Kanno 《Hemodialysis international. International Symposium on Home Hemodialysis》2018,22(3):388-393
Introduction : Topiroxostat, a recently developed xanthine oxidase inhibitor, is expected to have fewer adverse effects than allopurinol because it has different mechanism of action from alloprinol. However, its dosage, usage and safety have not been established in patients with impaired renal function or those undergoing dialysis at the development since no studies was conducted in these patients. Methods : Cross over clinical trial using 3 months of allopurinol and topiroxostat on 27 maintain Japanese HD patients were carried out. The effects on oxidative stress status of both drugs were also evaluated by measuring oxidation reduction potential. Findings : Twenty‐five of twenty‐seven patients completed study. The mean serum uric acid levels in the topiroxostat‐treated arm was significantly lower than it in the allopurinol‐treated arm time‐dependently (P < 0.0001). Corrected oxidative stress ratio defined as biological antioxidant potential/diacron reactive oxygen metabolites was significantly increased in topiroxostat‐arm (*P = 0.0035), but not in allopurinol‐arm (P = 0.1429). No significant difference was seen in diacron reactive oxygen metabolites, biological antioxidant potential, static oxidation‐reduction potential, and capacity oxidation‐reduction potential between pre and post treatment of both drugs. Discussion : It is suggested that a low dose of topiroxostat decreased serum uric acid sufficiently to maintain it below 7.0 mg/dL in patients receiving hemodialysis. 相似文献