Evaluation of capital cost data. part 7: Liquid waste disposal with emphasis on physical treatment

Capital cost correlations are given for oil-water separators, equalization basins, primary clarifiers, clarifiers and clarifier mechanisms, reverse osmosis unit, ultrafiltration units, gravity filters and miroscreens. Data are included for raw sewage, intermediate and recirculation pumping stations and for preliminary treatment (or bar screens, grit removal, overflow and bypass chamber and Parshall flume), for grit removal, comminution and gas stripping. The correlations are accurate to ± 30%, expressed in Canadian dollars and adjusted to a Marshall and Swift value of 1000. Details as to what components are included in the cost are given. Data are given for the labour and material costs to create a working process module. For inflation indices, a critique of the Engineering News Record, EPA small city, Marshall and Swift, Chemical Engineering and Southam inflation indices suggested that the Marshall and Swift index is most appropriate for the construction and process equipment studied here. Concerning the currency exchange, for the equipment and processes in this study, equipment costs the same whether expressed directly in US or Canadian dollars. To put the current data into perspective, several hundred sources of cost data were analyzed. The major correlations are compared, on a consistent basis, with current data.     

Evaluation of capital cost data: Heat exchangers

Capital cost correlations are given for heat exchangers and furnaces. Correlations available in the literature and current data are compared on a consistent basis. Forty-six graphs show the relative magnitude of the different correlations and the recommended correlation for each type of equipment is summarized in a table. Some data on the costs of installing heat exchange equipment are given.     

ANP and bradycardic reflexes in hypertensive rats: influence of cardiac hypertrophy

OBJECTIVES: Beta2-integrin (CD11b/CD18) expression, an indicator of neutrophil activation, has been associated with the development of acute respiratory distress syndrome. Leumedins act directly on leukocytes to inhibit the up-regulated expression of beta2-integrins involved in leukocyte adhesion. We examined the effect of such a new anti-inflammatory agent, NPC 15669 (N-[9H-(2,7-dimethylfluorenyl-9-methoxy)-carbonyl]-L-leucine), on neutrophil-mediated acute lung injury in an animal model. DESIGN: Prospective, randomized, blinded, controlled animal study. SETTING: An animal laboratory in a university setting. SUBJECTS: Adult New Zealand rabbits. INTERVENTIONS: After repeated lung lavages with normal saline to induce acute lung injury, anesthetized rabbits were randomly assigned to one of two groups (n = 6 per group): a) treatment group (pretreated with NPC 15669 [10 mg/kg i.v. bolus] 30 mins before lavage, followed by a continuous infusion [5 mg/kg/hr] for the duration [4 hrs] of the experiment); or b) control group (pretreatment and continuous infusion with placebo). All animals were mechanically ventilated with identical pressure settings over 4 hrs and were killed at the end of the experiment. MEASUREMENTS AND MAIN RESULTS: PaO2, PaCO2, and tidal volumes were repeatedly measured and airway pressure settings were noted every 30 mins. At the end of the experiment, lungs were taken out for measurements of the myeloperoxidase content, for conventional histology (hematoxylin and eosin staining), and for intracellular adhesion molecule-1 immunohistostaining. Pretreatment with NPC 15669 profoundly improved oxygenation from a PaO2 of 52 +/- 5 torr (6.9 +/- 0.7 kPa) to 250 +/- 161 torr (33.3 +/- 21.5 kPa) within 60 mins after lung lavage (p < .05). Oxygenation continued to improve throughout the study, reaching a maximal PaO2 value of 395 +/- 98 torr (52.7 +/- 13.1 kPa) at 4 hrs. In the control group, oxygenation remained poor throughout the observation period. PaO2 values differed significantly (51 +/- 20 torr [6.8 +/- 2.7 kPa] vs. 306 +/- 126 torr [40.8 +/- 16.8 kPa], p < .005) at 90 mins and at all subsequent measurements from those values in the NPC 15669 group. Dynamic lung compliance improved significantly 60 to 90 mins after repeated lung lavage. Histology demonstrated markedly less lung damage (hyaline membrane formation and leukocyte infiltration) in treated animals (p < .05) than in controls. CONCLUSIONS: NPC 15669 seems to block inflammatory reactions by inhibiting the sequestration of neutrophils in acute, ventilator-associated lung injury. As a result, gas exchange and total lung compliance improve. Application of this and similar compounds affecting neutrophil adhesion warrants further investigation as a treatment modality for acute lung injury.     

Thorium in the workplace: results from a European-based measurement comparison project

A Series of comparisons were conducted to test the capabilities of a range of metrological techniques and analytical laboratories engaged in the assay of thorium in the workplace. The results of these exercises are presented together with the decision criteria used to determine whether results are significantly different from the true value. The discussion highlights those aspects which warrant closer and further attention.     

More aggressive cartoons are funnier.

Independent rankings of humor and aggressiveness were obtained for sets of cartoons drawn randomly from 2 magazines. The correlation of median humor and median aggressiveness rankings ranged from .49 to .90 in 6 studies involving 6 sets of cartoons and 6 different groups of Ss, including children and adults, high and low SES individuals, and native- and foreign-born Ss. It was found that this correlation was consistent with Freudian, arousal, and superiority theories of humor. Another prediction of Freudian theory, that high-SES Ss should be more appreciative of aggressive humor than low-SES Ss, was not supported. (14 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Applying Plan Recognition Algorithms To Program Understanding

Program understanding is often viewed as the task of extracting plans and design goals from program source. As such, it is natural to try to apply standard AI plan recognition techniques to the program understanding problem. Yet program understanding researchers have quietly, but consistently, avoided the use of these plan recognition algorithms. This paper shows that treating program understanding as plan recognition is too simplistic and that traditional AI search algorithms for plan recognition are not suitable, as is, for program understanding. In particular, we show (1) that the program understanding task differs significantly from the typical general plan recognition task along several key dimensions, (2) that the program understanding task has particular properties that make it particularly amenable to constraint satisfaction techniques, and (3) that augmenting AI plan recognition algorithms with these techniques can lead to effective solutions for the program understanding problem.     

Using non-keyboard input devices: interviews with users in the workplace

A study of 45 non-keyboard input device (NKID) users was undertaken at nine organisations to investigate the extent, pattern and method of NKID usage, workstation configurations, postures adopted and musculoskeletal symptoms. A number of methods were used: work activity diaries, interviews, observations and postural assessments. A range of NKID were seen including the mouse, touchscreen, joystick, trackball, and tablet and pen; however, the mouse was the most commonly used device. Use of an input device varied from 2% to 100% of the working day. Workers undertook common tasks using a variety of methods (e.g. pull down menus, icons, device buttons). Users reported problems associated with the use of some devices, e.g. poor maintenance, lack of device responsiveness. Musculoskeletal pain and discomfort (e.g. stiffness and discomfort in the hands and wrist) was reported by 45% (n=19) of mouse users and 16% (n=5) of other NKID users. Workstation configurations varied and in some cases constrained the position of the input device, resulting in users having to work with the device at some distance away from the body. Despite the existence of regulations and guidance, this paper indicates that there are still many problems related to NKID use at computer workstations.

Relevance to industry

The reliance of many software applications on NKID (e.g. mouse, trackball, touchpad, joystick, touchscreen) necessitates the investigation of their use in the workplace. Whilst the performance aspects of NKID (e.g. speed) have been well researched, the possible implications for user health have received little attention in the UK.