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OBJECTIVES: To monitor the documentation of blood pressure measurements and other cardiovascular risk factors in general practice patients with hypertension. METHOD: Twenty-five case notes of patients diagnosed as hypertensive were randomly selected from each of 58 participating general practitioners in suburban general practice in Adelaide, South Australia and were monitored by two registered nurses. Main outcome measures: to assess whether blood pressure readings, weight, smoking history, alcohol intake and family history were documented, and whether electrocardiogram, plasma lipids, urinalysis and biochemical screen (which includes blood urea nitrogen, creatinine, glucose, electrolytes and uric acid) had been undertaken. RESULTS: Data from 1446 hypertensive patients showed that for the last three blood pressure values recorded, 483 (33%) had an average level of 140/90 mm Hg or less and 1100 (76%) had an average of 160/95 mm Hg or less. The other cardiovascular risk factors selected were variably recorded, with biochemical screen being most commonly recorded [1198 (83%)] and family history [423 (29%)] the least. CONCLUSIONS: Inadequacies in the control of hypertension and in the documentation of other cardiovascular risk factors suggest that further educational initiatives are required in this common chronic illness. 相似文献
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SF An B Giometto M Groves RF Miller AA Beckett F Gray B Tavolato F Scaravilli 《Canadian Metallurgical Quarterly》1997,56(11):1262-1268
The presence of neuropsychological disturbances in HIV-positive, pre-symptomatic individuals is a controversial issue. Neuroimaging studies have not shown brain atrophy or hyperintensity in the white matter, whereas proton magnetic resonance spectroscopy has revealed some abnormality of cerebral biochemistry. Using an antibody to beta-amyloid precursor protein (beta-APP), we previously demonstrated frequent and widespread axonal changes in the brains of AIDS patients. In this study, we extended the use of beta-APP to asymptomatic patients in order to establish a possible morphological correlation with neuropsychological disorders. Brain samples from 29 patients were examined. Results showed bundles of beta-APP-positive axons in 8/29 cases (27%). The changes, seen in both superficial and deep white matter, were either focal or diffuse, could not be visualized by silver or ubiquitin stains, and did not coexist with any change in distribution or morphology of astrocytes and microglial cells. We conclude that in HIV-positive asymptomatic individuals, axonal changes: (a) may be related to the state of immune activation with consequent presence of toxic substances, including cytokines, observed in these patients; (b) may represent mild changes that could undergo repair, unless other pathological events, such as the supervening of the AIDS stage and the specific encephalitis, make them permanent. 相似文献
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The method of determination of the gamma-radiation absorption distribution in microstructures of a biosystem is proposed. The absorption capacity and energy absorption distribution of some biomolecules, mass coefficients and optical density of blood and thyroid gland are calculated. Influence of the pollution of biosystem microstructures (liver, blood, thyroid, gland) by hard elements on the energy absorption distribution is demonstrated. 相似文献
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A 9-month-old boy with a primary cystic lymphangioma of the right kidney is reported. The clinical and radiological features favored a malignant tumor. Histology revealed the lesion to be a lymphangioma; the diagnosis was confirmed by immunohistochemistry and chemical analysis of the intracystic fluid. Lymphangiomas of the kidney are rare in adults; they are even rarer in infants and children. Nevertheless, renal lymphangiomas should be considered in the differential diagnosis of multicystic, unilateral renal masses, independent of the age of the patient. 相似文献