Fluid/Structure Interaction Computational Investigation of Blast-Wave Mitigation Efficacy of the Advanced Combat Helmet

To combat the problem of traumatic brain injury (TBI), a signature injury of the current military conflicts, there is an urgent need to design head protection systems with superior blast/ballistic impact mitigation capabilities. Toward that end, the blast impact mitigation performance of an advanced combat helmet (ACH) head protection system equipped with polyurea suspension pads and subjected to two different blast peak pressure loadings has been investigated computationally. A fairly detailed (Lagrangian) finite-element model of a helmet/skull/brain assembly is first constructed and placed into an Eulerian air domain through which a single planar blast wave propagates. A combined Eulerian/Lagrangian transient nonlinear dynamics computational fluid/solid interaction analysis is next conducted in order to assess the extent of reduction in intra-cranial shock-wave ingress (responsible for TBI). This was done by comparing temporal evolutions of intra-cranial normal and shear stresses for the cases of an unprotected head and the helmet-protected head and by correlating these quantities with the three most common types of mild traumatic brain injury (mTBI), i.e., axonal damage, contusion, and subdural hemorrhage. The results obtained show that the ACH provides some level of protection against all investigated types of mTBI and that the level of protection increases somewhat with an increase in blast peak pressure. In order to rationalize the aforementioned findings, a shockwave propagation/reflection analysis is carried out for the unprotected head and helmet-protected head cases. The analysis qualitatively corroborated the results pertaining to the blast-mitigation efficacy of an ACH, but also suggested that there are additional shockwave energy dissipation phenomena which play an important role in the mechanical response of the unprotected/protected head to blast impact.     

Characterization of film-coated aerosol canisters using electrochemical impedance spectroscopy

Drug adhesion to the walls of an aerosol canister can be prevented/reduced by coating the canister with a hydrophobic polymer (e.g., a fluoropolymer). In this study, three batches of fluoropolymer-coated canisters were investigated by electrochemical impedance spectroscopy (EIS) and scanning electron microscopy (SEM). The EIS technique showed that only one of the batches presented as a monolithic, non-porous film. The other two batches were either partially porous or highly porous. Scanning electron micrographs showed evidence of cracks, within the films, but could not alone establish the porous nature of these defects. For the non-porous and partly porous films it was possible to use the EIS data to determine the approximate film thickness. Estimates of 2-4 µm were obtained for the mean film thickness. These values compared favorably with micrometer estimates obtained following acid dissolution of the aluminum canister. It remains to be seen whether the properties of the films (i.e., the porosity and film thickness, determined by EIS) translate to differences in drug adhesion. Nevertheless, the EIS technique was shown to be a powerful, non-destructive method that lends itself to the rapid analysis of batch-to-batch variation in film-coated canisters.     

Relationships among team ability composition, team mental models, and team performance.

This study examined the relationship between the similarity and accuracy of team mental models and compared the extent to which each predicted team performance. The relationship between team ability composition and team mental models was also investigated. Eighty-three dyadic teams worked on a complex skill task in a 2-week training protocol. Results indicated that although similarity and accuracy of team mental models were significantly related, accuracy was a stronger predictor of team performance. In addition, team ability was more strongly related to the accuracy than to the similarity of team mental models and accuracy partially mediated the relationship between team ability and team performance, but similarity did not. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

运营商可信赖的3G伙伴--上海贝尔阿尔卡特

对于3G网络运营商来说，网络是其最重要的竞争资源，低成本、高质量的3G网络是其成功运营获得丰厚利润的基础。因此，设备供应商是3G网络运营商在整个价值链上最为重要的合作伙伴。一个值得运营商长期信赖的3G网络设备供应商应该具有如下四个方面的特征：成熟的网络解决方案、出色的网络规划与优化、丰富的应用业务支持和强大的综合实力。     

Influences Impacting Leadership Development

The construction industry is placing increased emphasis on developing leadership skills for project managers. This paper describes a research project that was executed to analyze the causal influences on the development of project managers, whom the authors believe also must be leaders. The research compared two groups of project managers within a large construction company. One group was top performing construction managers as selected by corporate executives, while the second group was a randomly selected control group. The research examined influences on career development including job experience, project management experience, formal project management training, formal leadership training, and job assignments. The research also solicited opinions from both groups as to what they perceived as factors impacting leadership career development. Statistical differences between the groups were found in the areas of project management experience and number of positions held prior to the first project management assignment. Both groups believed there was more of a need within their company for leadership training than for project management training.     

Two-dimensional profiles of fumonisin B1 production by Fusarium moniliforme and Fusarium proliferatum in relation to environmental factors and potential for modelling toxin formation in maize grain

This study has examined in detail the effect of temperature (7-37 degrees C) and water availability (water activity, a(w), 0.89-0.97) on fumonisin B1 (FB1) production by an isolate of Fusarium moniliforme and F. proliferatum on irradiated maize grain after incubation for 28 days. The optimum conditions for F. moniliforme and F. proliferatum were 30 degrees C at 0.97 a(w) and 15 degrees C at 0.97 a(w), respectively. The maximum concentrations were 2861 mg kg(-1) and 17,628 mg kg(-1) dry wt. maize grain, respectively. At marginal a(w)/temperature conditions for growth (e.g. 0.89-0.91 a(w)) no FB1 was detected (<0.1 mg kg(-1)). A high variability was found between replicates for F. moniliforme, but not for F. proliferatum. These data were used to construct two-dimensional diagrams of all the a(w) x temperature conditions favourable for FB1 production for the first time. The data were also subjected to a polynomical regression, which demonstrated that there was a very good fit for the 15-30 degrees C range of temperature and at 0.97 a(w). However, at marginal environmental conditions this was not possible. This suggests that it may be possible to predict within a limited environmental range the potential for significant FB1 production.     

Elastic-plastic characterization of thin films with spherical indentation

Indentation characterization of thin films has most recently been investigated with currently available ultramicroindentation hardness instruments that use a pyramidal diamond tipped indenter. With these instruments determination of the hardness at depths of penetration as shallow as 5–10 nm is possible. However, the problems associated with such indenters are the inability to characterize the indenter tip radius and the fact that pointed indenters essentially perform tests at constant plastic strain. An alternative approach to measuring the mechanical properties of thin films is to use spherically tipped indenters of known tip radius and to follow the transition from elastic to plastic deformation. The Hertzian analysis provides the basis for determining the elastic behaviour and it may be modified to examine the elastic-plastic transition. From such observations it is possible to determine the variation in the mean indentation pressure with depth of penetration and to construct an equivalent stress-strain response of a material. Examples of this approach are given for bulk materials and metallic and polymeric thin films. Data have been collected with a UMIS-2000 instrument and have been analysed and simulated on the basis of the approach outlined above.     

Preparation and in vitro characterization of gentamycin-impregnated biodegradable beads suitable for treatment of osteomyelitis

A new method for preparing poly(L-lactide) (PLA) biodegradable beads impregnated with an ionic aminoglycoside, gentamycin, is described. The process employs hydrophobic ion pairing to solubilize gentamycin in a solvent compatible with PLA, followed by precipitation with a compressed antisolvent (supercritical carbon dioxide). The resulting precipitate is a homogeneous dispersion of the ion-paired drug in PLA microspheres. The microspheres are approximately 1 microm in diameter and can be compressed into beads (3-6 mm in diameter) strung on surgical sutures for implantation. The bead strings exhibit no significant change in release kinetics upon sterilization with a hydrogen peroxide plasma (Ster-Rad). The kinetics of gentamycin release from the PLA beads are consistent with a matrix-controlled diffusion mechanism. While nonbiodegradable poly(methyl methacrylate) (PMMA) beads initially release gentamycin in a similar manner, the drug release from PMMA ceases after 8 or 9 weeks, while the PLA beads continue to release drug for over 4 months. Moreover, only 10% of the gentamycin is released from the PMMA beads, while PLA beads release more than 60% of their load, if serum is present in the release medium. The PLA system displays improved release kinetics relative to PMMA, is biodegradable, is unaltered by gas sterilization, can be used for a range of antibiotics, and can be manipulated without disintegration. These are all desirable properties for an implantable drug delivery system for the prevention or treatment of osteomyelitis.