2-Hydroxyhexadecanoic and 8,9,13-trihydroxydocosanoic acid accumulation by yeasts treated with fumonisin B1

Fumonisin B₁ is a sphingolipid-like compound that enhances the accumulation of yeast sphingolipids and 2-hydroxy fatty acids. These lipids occur both as freely extractable and cell bound components in yeast fermentations. Both free and bound 2-hydroxy fatty acids produced byPichia sydowiorum NRRL Y-7130 were increased when fumonisin B₁ (50 mg/L) was added to the usual growth medium containing yeast extract/malt extract/peptone/glucose. Fumonisin-treated cultures contained 38 mg/L more 2-hydroxyhexadecanoic and 15 mg/L more 2-hydroxyoctadecanoic acids than did untreated cultures. By contrast, fumonisin inhibited the accumulation of free 8,9,13-trihydroxydocosanoic acid inRhodotorula sp. YB-2501 cultures, leading to 240 mg/L lower trihydroxy acid production than by untreated cultures.     

Prepreg aging in relation to tack

Thermoanalytical measurements and tack tests were both performed using a commercially available carbon fiber/epoxy prepreg system (Hercules 3501–6) to examine changes caused by aging as they affect handling and processability of thermosetting matrix-based composites. Combining these techniques, a relationship between prepreg bulk and surface characteristics in relation to aging was investigated. Isothermal kinetic studies at low temperatures showed maximum conversions (α_m) that increased with increasing cure temperatures. In addition, a linear relationship between glass transition temperatures (T_g) and conversions (α) was observed regardless of aging (or cure) temperatures. Energy of separation of prepreg stacks, which may be viewed as a measure of prepreg tack, showed a maximum value at a specific temperature. The maximum energy of separation was observed in the temperature range of 20–25°C above the glass transition temperature for a given sample. However, the maximum energy of separation values decreased with increasing aging times (or conversions), implying that prepreg tack was a viscoelastic property rather than a viscous property of the resin matrix in the prepreg.     

The U-Zr (Uranium-Zirconium) system

This work was supported by the Department of Energy through the Joint Program on Critical Compilations of Physical and Chemical Data, coordinated through the Office of Standard Reference Data (OSRD), National Institute of Standards and Technology. Literature searched through 1985. Dr. Peterson is the ASM/NIST Data Program Category Editor for binary actinide alloys.     

The Cm-Pt (Curium-Platinum) system

Work was supported by the Department of Energy through the Joint Program on Critical Compilations of Physical and Chemical Data, coordinated thorugh the Office of Standard Reference Data (OSRD), National Institute of Standards and Technology. Literature searched through February 1987. Dr. Peterson is the ASM/NIST Category Editor for binary actinide alloys.     

The Pb−Pu (Lead-Plutonium) system

This work was supported by the Department of Energy through the Joint Program on Critical Compilations of Physical and Chemical Data, coordinated through the Office of Standard Reference Data, National Bureau of Standards. Literature searched through 1984. Dr. Peterson is the ASM/NBS Data Program Category Editor for binary actinide alloys.     

Accessing Egypt: making myths and producing web sites in cyber-Cairo

From an anthropological viewpoint, “accessibility” is not so much a technological and design project as it is a cultural construction, a cognitive schema through which graphic designers and technologists imagine audiences and create appropriate graphic designs that will be “accessible” to that audience. The ethnographer's task is the specification of key actors, institutions and discourses active in the making and remaking of accessibility in a given context. In this article, we examine how Egyptian Web producers at the turn of millennium (1999–2001) sought to design Web portals that would allow the “typical” Egyptian to easily access the World Wide Web. We argue, first, that Egyptian Web producers are deeply influenced by national and international discourses that frame IT as a national mission for socioeconomic development. Second, we found that in the absence of clear definitions of the Web audience, Web producers imagined a “typical” Egyptian that contradicted their own experiences of users of the Web. Finally, we found that Egyptian Web producers largely borrowed pre-existing models, using design elements to “inflect” their sites with an Egyptian motif. However, the conceptual models of access and related design strategies created by Egyptian Web producers were out of touch with Egyptian social realities, contributing to a collapse of most Web portal projects.     

The experimental research of a digital sampling signal converter

The sensitivity and rise time of a transient characteristic of a digital sampling signal converter are experimentally researched. The sampling converter is built at a clocked tunnel-diode comparator.     

The biological properties of Aerococcus antagonists, representatives of human microbiocenoses

The paper deals with the data on biology of Aerococcus, a slightly studied group of microorganisms. Physiological-biochemical properties of Aerococcus are described, data of their distribution in nature are given. Peculiar attention is paid to the estimate of the role of Aerococcus in human microbiocenoses. As a result of the profound and all-round study of this group of microorganisms the authors have developed new bacterial drug "A-bakterin" based on the aerococcus strain. Data presented about the results of clinical tests of "A-bakterin" are presented, a possibility to use Aerococcus lysate in the elaboration of new drugs is discussed.     

The effect of combined antenatal vitamin K and phenobarbital therapy on umbilical blood coagulation studies in infants less than 34 weeks' gestation

OBJECTIVE: To determine if antenatal vitamin K and phenobarbital therapy affect coagulation studies in umbilical blood at birth, and to provide 95% reference ranges for umbilical blood coagulation parameters in premature gestations. METHODS: Patients at imminent risk for spontaneous or indicated premature delivery less than 34 weeks' gestation were randomized to receive either placebo or vitamin K and phenobarbital. Prothrombin time (PT), activated partial thromboplastin time (PTT), functional coagulation factors, and decarboxylated prothrombin assays were performed on umbilical blood specimens. Decarboxylated prothrombin, also known as "protein induced by vitamin K absence-factor II" or precursor prothrombin, is a sensitive marker for vitamin K deficiency. Standardized values of PT and PTT are reported in seconds and standardized values of factor assays in percentage of normal adult functional activity (mean +/- one standard deviation). RESULTS: Newborns in the placebo and treatment groups had similar umbilical blood PT (12.6 +/- 1.2 versus 12.7 +/- 1.4 seconds), PTT (48.8 +/- 13.4 versus 49.6 +/- 13.8 seconds), and functional activity of factor II (40.3 +/- 12.5 versus 42.0 +/- 12.1%), factor VII (67.0 +/- 20.9 versus 66.8 +/- 18.9%), factor IX (27.4 +/- 12.8 versus 25.8 +/- 8.9%), and factor X (47.0 +/- 12.8 versus 49.2 +/- 11.6%). Newborns in the treatment group were about half as likely as those in the placebo group to have detectable decarboxylated prothrombin levels in umbilical blood at birth (gestational age-adjusted odds ratio 0.47, 95% confidence interval 0.22-1.01; P = .05). CONCLUSIONS: Combined maternal therapy with vitamin K and phenobarbital before premature delivery does not affect umbilical blood PT, PTT, or functional activity of vitamin K-dependent coagulation factors II, VII, IX, and X. However, it is associated with the reduced presence of decarboxylated prothrombin in umbilical blood at birth. There is significant improvement in umbilical blood coagulation tests as gestational age advances from 24 to 34 weeks.