Growth and characterization of GaSb bulk crystals with low acceptor concentration

GaSb bulk single crystals with low acceptor concentration were grown from a bismuth solution by the traveling heater method. The result is isoelectronic doping by Bi which gives a variation of the opto-electronic properties as a function of grown length as well as a pronounced microscopic segregation. Photoluminescence spectra at 4K show a decrease of the natural acceptor during growth, which is confirmed by Hall measurements. The electrical properties of this isoelectronic doped GaSb are hole concentrations and mobilities of N_A − N_D = 1.7 × 10¹⁶ cm⁻³ and μ = 870 cm²Vs at room temperature and N_A-N_D = 1 × 10¹⁶ cm⁻³ and μ = 4900 cm²/Vs at 77K, respectively. The lowest p-type carrier concentration measured at 300K is N_A − N_D = 3.3 × 10¹⁵ cm⁻³     

Percutaneous balloon pericardiotomy for patients with recurrent pericardial effusion: using a novel double-balloon technique with one long and one short balloon

Percutaneous balloon pericardiotomy is effective and less invasive for the treatment of recurrent pericardial effusion. This study suggests that the double-balloon method with 1 longer and 1 shorter balloon is the procedure of choice for percutaneous balloon pericardiotomy.     

Effects of gemfibrozil and ciprofibrate on plasma levels of tissue-type plasminogen activator, plasminogen activator inhibitor-1 and fibrinogen in hyperlipidaemic patients

Evaluation of fibrate treatment in humans has focused primarily on its anti-lipidaemic effects. A potentially favourable haemostasis-modulating activity of fibrates has also been recognized but the data are not consistent. We sought to learn more about this variability by examining the effects of gemfibrozil and ciprofibrate on plasma levels of tissue-type plasminogen activator (t-PA), plasminogen activator inhibitor-1 (PAI-1) and fibrinogen in primary hyperlipidaemic patients after six and twelve weeks of treatment using different assay systems for PAI-1 and fibrinogen. Although both fibrates effectively lowered triglyceride and cholesterol levels, no effect on the elevated baseline antigen levels of t-PA and PAI-1 was observed after fibrate treatment. However, both fibrates influenced plasma fibrinogen levels, albeit in a different way. Fibrinogen antigen levels were elevated by 17.6% (p <0.05) and 24.3% (p <0.001) with gemfibrozil after six and twelve weeks, respectively, whereas with ciprofibrate there was no effect. Using a Clauss functional assay with either a mechanical end point or a turbidity-based end point, no significant change in fibrinogen levels was seen after six weeks of gemfibrozil treatment. However, after twelve weeks, gemfibrozil enhanced functional fibrinogen levels by 7.2% (p <0.05) as assessed by the Clauss mechanical assay, but decreased functional fibrinogen levels by 12.5% (p <0.0001) when a Clauss assay based on turbidity was used. After six or twelve weeks of ciprofibrate treatment, functional fibrinogen levels were decreased by 10.1% (p <0.001) and 10.5% (p <0.0001), respectively on the basis of Clauss mechanical and by 14.2% (p <0.001) and 28.2% (p <0.0001), respectively with the Clauss turbidimetric assay. A remarkable and consistent finding with both fibrates was the decrease in functionality of fibrinogen as assessed by the ratio of functional fibrinogen (determined by either of the two Clauss assays) to fibrinogen antigen. Taken together, our results indicate that at least part of the variability in the effects of fibrates on haemostatic parameters can be explained by intrinsic differences between various fibrates, by differences in treatment period and/or by the different outcomes of various assay systems. Interestingly, the two fibrates tested both reduced the functionality of fibrinogen.     

Heat exchangers for he II cooling loops with self-sustained fountain effect pumps

A cooling cycle with He II convection driven by self-sustained fountain effect pumps is being investigated. Special attention is drawn to the problem of heat transfer at both ends of the superfilter of this loop. The heat exchanger requirements are derived from theoretical considerations on the degradation of the cooling characteristic effected by non-perfect heat exchangers. A shell and tube type heat exchanger, optimized for the warm end of the filter has been operated in this loop with a thermal load of up to 9 W, with 2.8 g s⁻¹ maximum helium flow rate and with inlet temperatures between 1.8 and 3.4 K. Its performance is well described by computations. A different heat exchanger design with finned Cu walls is suggested for the cold end of the pump. Some considerations on its optimization are given.     

Einsatz moderner Informationstechnik im militärischen Bereich: Für den Verteidiger notwendig und verantwortbar

Zusammenfassung Nach Pädagogen, Ärzten etc. haben sich nun auch Informatiker für den Frieden organisiert. So sehr sich der Verfasser mit den Zielen von Friedensinitiativen identifizieren kann, so sieht er doch die Gefahr, daß diese Bemühungen insgesamt eher destabilisierend und damit kontraproduktiv wirken. Bevor im folgenden Beitrag dieser Gedankengang weiter ausgeführt wird, soll zunächst versucht werden, die Bereiche darzustellen, in denen bislang und in absehbarer Zukunft Rechensysteme in modern ausgerüsteten Streitkräften eingesetzt werden, wobei besonders auf die Situation in Mitteleuropa und speziell auf die Bundeswehr eingegangen wird. Es wird aufgezeigt, daß gerade der Verteidiger auf moderne Führungs- und Aufklärungssysteme angewiesen ist, insbesondere in der kritischen Anfangsphase eines Konflikts, und daß die Vertreter alternativer Verteidigungsstrukturen, die den Schwerpunkt auf defensiv ausgerüstete Verbände mit struktureller Nichtangriffsfähigkeit legen, wie auch offizielle Programme der NATO zur Verbesserung der konventionellen Verteidigungsfähigkeit auf moderne Technologie setzen. In diesem Zusammenhang wird ein Forschungsprojekt vorgestellt, das zum Ziel hat, die Wirksamkeit derartiger reaktiver, rüstungskontrollfreundlicher Verteidigungs- und Bewaffnungsstrukturen sowie moderner Technologie im Gefecht der verbundenen Waffen zu untersuchen. Entsprechend der Themenstellung dieses Sonderheftes soll schließlich auch auf moralisch-ethische Aspekte des Einsatzes moderner Informationstechnik für die Verteidigungsplanung eingegangen werden. Dies geschieht in der Form von Thesen, um die Aussagen als persönliche Meinung des Verfassers besonders zu kennzeichnen.     

From the history of electrocardiography

The basis of electrocardiography was established in the innovative years between 1850 and 1930. Men like Waller, DuBois-Reymond, and Einthoven were the innovators of what we today recognize as modern electrocardiography. Others, like Lewis and Bedford, introduced analysis of cardiac arrhythmias, of the S-T segment and the QRS complex. The article gives an overview of this innovative period and its instrumentation.     

A decade of clinical trial developments in postmyocardial infarction, congestive heart failure, and sustained ventricular tachyarrhythmia patients: from CAST to AVID and beyond. Cardiac Arrhythmic Suppression Trial. Antiarrhythmic Versus Implantable Defibrillators

Multiple trials using antiarrhythmic drugs, pharmacologic therapy, and implantable cardioverter defibrillators have been performed in an attempt to improve survival in patients: (1) postmyocardial infarction; (2) with congestive heart failure, with and without nonsustained ventricular tachycardia; and (3) with sustained ventricular tachycardia and those who have survived an out-of-hospital cardiac arrest. This article reviews some of the key findings and limitations of completed and ongoing trials. We also make recommendations for the current treatment of such patients based on the results of these trials.     

Comparison of calcium phosphate cement mixture and pure calcium hydroxide as direct pulp-capping agents

This review reports the different genetic factors that have been identified either as risk factor for Alzheimer's disease (AD) or directly causing the disease. First are reviewed epidemiological data and biological mechanisms about the apoplipoprotein E gene allele epsilon 4 that is a major risk factor for Alzheimer's disease. The second part describes the mutations responsible for early-onset autosomal dominant AD found in three different genes. The gene located on chromosome 21 encodes the amyloid precusor protein (APP). The presenilin 1 and presenilin 2 genes, located on chromosome 14 and 1 respectively, encode not yet known membrane proteins.