The effects of royal jelly on liver damage induced by paracetamol in mice

The present study was undertaken to investigate the protective effect of royal jelly against paracetamol-induced liver damage. The study was conducted in 90 female Swiss Albino mice, and six groups were established. While the first group was maintained as control, Groups 2–6 were administered 200 mg/kg RJ for 1 day, 200 mg/kg RJ for 7 days, 400 mg/kg PAR for 1 day, 200 mg/kg RJ plus 400 mg/kg PAR for 1 day and 200 mg/kg RJ for 7 days and then second 400 mg/kg PAR on the 7th day, orally, respectively. It was shown that PAR significantly increased serum ALT, AST, ALP, liver MDA levels and significantly decreased liver GSH-Px activity, when compared to the control group (Group 1). On the other hand, meaningful changes were observed in the biochemical parameters of the group which was administered long-term RJ (Group 6). The aforementioned parameters which were statistically significant were determined to have drawn closer to values of the control group, and among these, the existing statistical differences for MDA level and GSH-Px activity between the trial group (Group 6) and the control group disappeared (Group 1). Compared to the pathological changes observed in the liver parenchyma, remark cords, sinusoids and hepatocytes in the group which was administered paracetamol alone (Group 4), lesions were determined to be less severe particularly in the group (Group 6) which received royal jelly for 7 days prior to paracetamol. In conclusion, the administration of royal jelly as a hepatoprotective agent for 7 days against paracetamol-induced liver damage was determined to exhibit marked protective effect on liver tissue.     

Evaluation of protective effect of bee pollen against propoxur toxicity in rat

In this study, 28 Wistar female rats (200-250g) were used and divided into four equal groups. Group 1 was allocated as the control group. Groups 2-4 were administered 100mg/kg/bw/day bee pollen, 20mg/kg/bw/day propoxur, and 100mg/kg/bw/day bee pollen plus 20mg/kg/bw/day propoxur by gavage for 14 days, respectively. At the end of the 14th day, blood and tissues (the liver, kidney, brain, and heart) were collected from all animals. Oxidative stress markers (MDA, CAT, SOD, GSH-Px) and some other biochemical parameters (total protein, albumin, glucose, cholesterol, triglyceride, BUN, creatinine, uric acid, magnesium, sodium, potassium, chloride, total bilirubin, GGT, LDH, AST, ALT, and ALP) were analyzed. According to the data obtained, propoxur was determined to lead to negative changes in most of the biochemical parameters investigated and the administration of bee pollen was determined to alleviate these effects.     

Antioxidant effect of propolis against exposure to propetamphos in rats

In the present study, each group comprised six animals, and a total of 30 female. Wistar Albino rats weighing 200-250g were used. The first group served as the control group. Group 2 received propolis at a concentration of 100mg/kgbw/day in drinking water. Groups 3 and 4 were administered propetamphos at doses of 7.5 and 15.0mg/kgbw/day, respectively, in drinking water. Group 5 was treated with propetamphos at a dose of 15.0mg/kgbw/day, in association with 100mg/kgbw/day propolis in drinking water. Treatment was continued for 28 days, and at the end of this period, blood and tissue (liver, kidney and brain) samples were collected. Plasma and tissue MDA levels and erythrocyte and tissue SOD, CAT, and GSH-Px activities were measured. In conclusion, the administration of propolis was concluded to exhibit antiradical and antioxidant effect, and thereby to result in the alleviation of oxidative stress.     

论肥胖病治疗之“三关”

在传统理论的基础上提出了治疗肥胖病之"三关",并详细的介绍了其形成的基础、主要内涵、运用及临床指导意义.     

疏肝健脾汤联合马来酸曲美布汀治疗腹泻型肠易激综合征60例

目的:探讨中西医结合治疗腹泻型肠易激综合征(IBS)的临床疗效.方法:将60例患者随机分为治疗组与对照组,每组30饲,时照组予以马来酸曲美布汀片口服,治疗组在对照组基础上加服自拟疏肝健脾汤,疗程60 d,疗程结束后对比两组患者的临床疗效.结果:治疗组临床疗效明显优于对照组(P<0.05).结论:自拟方疏肝健脾汤联合马来酸曲美布汀片治疗腹泻型肠易激综合征临床疗效确切.     

中药灌肠治疗慢性前列腺炎(气滞血瘀型)临床研究

目的:观察中药保留灌肠治疗慢性前列腺炎的效果.方法:治疗组65例以左氧氟沙星胶囊加行气活血化瘀中药保留灌肠治疗,对照组40例用左氧氟沙星胶囊治疗.结果:两组治愈率有显著性差异(P＜0.05).治疗期间两组病人均未发生不良反应.结论:中药保留灌肠治疗慢性前列腺炎有一定疗效.     

黄芪多糖对肿瘤免疫调节作用的研究进展

为了探讨黄芪多糖时肿瘤免疫调节作用及部分作用机制.本文阅读了国内外有关文献并进行综述,得出黄芪多糖具有明显的免疫促进、双向调节的多方面作用,并对调节肿瘤免疫有重要作用.     

建设“以病人为中心”的医院服务文化

介绍医院在服务文化的营造与培养;优化服务程序,提高服务效率;发挥思想政治工作的导向作用和规章制度的约束作用等方面的理念、做法和成效。