瑞芬太尼静脉自控式分娩镇痛的临床研究

The study intended to evaluate the efficacy and safety of patient-controlled intravenous analgesia with remifentanil for labor. Three hundred and two parturients at 37 -42 week of gestation received remifentanil (0. 1μg · kg-1 ·min-1 ) as patient-controlled intravenous analgesia for labor (analgesia group) and their clinical results were compared with those of 221 parturients in labor without intravenous analgesia (control group). Maternal monitoring, including pain scores(VAS), delivery mode, side effects, laboring time was performed for both groups. There was a significant decrease (P ＜0. 01) of pain scores in analgesia group compared with those in control group. Parturients in analgesia group experienced a significantly shorter first stage, than those in the control group ( P ＜ 0. 01). There were no differences between two groups in the rate of cesarean section and instrumental delivery. And there were no significant differences for newborns with Apgar scores less than 7 at the point of one minute. Patient-controlled intravenous analgesia with remifentanil for labor is an effective and safe procedure, which can significantly relieve pain, shorten first stage of labor and has no effect on the delivery mode and Apgar scores of neonates.     

不同分娩方式对婴幼儿智能和体格发育影响的探讨

目的：研究不同分娩方式对婴幼儿智能和体格发育的影响。方法：用Ｇｅｓｅｌ婴幼儿发育检查量表测出顺产组、胎吸组、产钳组、胎吸加产钳组婴幼儿的智能发育商（ＤＱ），并分别测出其体重、身长，调查其智能发育的影响因素。结果：４组婴幼儿的ＤＱ经方差分析存在显著性差异，Ｆ＝６．２３，Ｐ＜０．０１，而各组婴幼儿的体重、身长之间相比无统计学上的差异。影响智能发育因素经逐步回归分析得出显著因子是：分娩方式、早期教育开始年龄及入托情况。结论：不同的分娩方式对婴幼儿的智能发育有一定的影响。     

瑞芬太尼静脉自控式分娩镇痛的临床研究

The study intended to evaluate the efficacy and safety of patient-controlled intravenous analgesia with remifentanil for labor. Three hundred and two parturients at 37 -42 week of gestation received remifentanil (0. 1μg · kg-1 ·min-1 ) as patient-controlled intravenous analgesia for labor (analgesia group) and their clinical results were compared with those of 221 parturients in labor without intravenous analgesia (control group). Maternal monitoring, including pain scores(VAS), delivery mode, side effects, laboring time was performed for both groups. There was a significant decrease (P ＜0. 01) of pain scores in analgesia group compared with those in control group. Parturients in analgesia group experienced a significantly shorter first stage, than those in the control group ( P ＜ 0. 01). There were no differences between two groups in the rate of cesarean section and instrumental delivery. And there were no significant differences for newborns with Apgar scores less than 7 at the point of one minute. Patient-controlled intravenous analgesia with remifentanil for labor is an effective and safe procedure, which can significantly relieve pain, shorten first stage of labor and has no effect on the delivery mode and Apgar scores of neonates.     

Foley''''s导尿管对妊娠晚期促宫颈成熟引产的观察

宫颈成熟与否是妊娠晚期引产成败的关键，若处理不当，可增加母婴并发症。宫颈评分低于4分引产的成功率很低。本组采用Foley，s导尿管对45例宫颈评分＜4分的妊娠晚期孕妇促宫颈成熟引产，与低剂量催产素引产进行对照，观察其效果与安全性，现总结如下。资料与方法一、对象：自1995年7月至1997年6月在圭也那林顿联合医院对有引产指征的孕妇，年龄20～30岁，孕32～44周，均为初产妇，骨盆测量无异常，宫颈BISh。p评分wt4分，采用Foley）s导尿管促宫颈成熟45例为研究组，小剂量催产素促宫颈成熟30例为对照组。二、方法：1．研究组：根据宫颈…     

改良式子宫下段剖宫产术287例临床分析

为了解改良式子宫下段剖宫产术临床应用价值，对287例改良式子宫下段剖它产术病例进行详细分析。结果表明，改良式子宫下段剖宫产术手术时间短、损伤小、术中出血少、腹部伤口瘢痕纤细、美观，病人术后恢复快。该结果提示该术式在临床上有很高的应用和推广价值。     

胎儿宫内生长迟缓时孕妇血及脐血中一氧化氮水平与胎儿脐血流S/D值的关系

目的　了解胎儿宫内生长迟缓 (IUGR)时 ,孕妇血及脐血中一氧化氮 (NO)水平与胎儿脐血流S/D值的关系 ,以进一步探讨IUGR时胎盘循环阻力增高的原因。方法　对 33例妊娠合并胎儿宫内生长迟缓 (IUGR组 )及 32例正常孕妇 (对照组 ) ,用镉还原显色法测定母血及脐血NO水平 ,超声多普勒测定胎儿脐血流S/D值。结果　IUGR组母血及脐血NO水平均明显低于对照组(P <0 0 1,P <0 0 1) ,母血与脐血NO水平有相关性 (r =0 6 16 41,P <0 0 1) ;IUGR组脐血流S/D值明显高于对照组 (P <0 0 1) ,母血及脐血NO水平与S/D值呈负相关 (r =- 0 30 90 7,r =-0 44 44 9,P <0 0 1,P <0 0 1)。结论　IUGR时 ,母血及脐血中NO水平降低导致胎儿—胎盘血循环阻力增高 ,脐动脉舒张期末血流减少 ,脐血流S/D值增高。     

称重法和目测法在计算产后出血量的差异

产后出血是产科最危险的并发症之一,占全国孕产妇死亡原因的首位。对每位产妇产后出血量作出正确的统计,是对产后大出血的预防、治疗及预后评估的关键,充分评估高危孕产妇的风险,预防产后出血发生,在抢救产后大出血患者时,做到快速有效,尽可能减少出血,从而降低孕产妇病死率。介于     

微小RNAs与多囊卵巢综合征发病机制的研究进展

微小RNA(micro RNAs,mi RNAs)参与基因转录后表达调控。多囊卵巢综合征(PCOS)为一种异质性疾病,其发病机制尚不明确。多种mi RNAs在PCOS患者血清、颗粒细胞以及卵泡液中表达异常,提示mi RNAs参与PCOS的病理过程。mi RNAs与多种卵巢甾体激素的合成与分泌关系密切;参与卵泡的发育和闭锁,从而影响PCOS患者的排卵过程;还在胰岛素抵抗中发挥重要作用。mi R-125b、mi R-483和mi R-320通过调控多种靶基因而影响多条信号通路。综述mi RNAs在PCOS发病机制中的作用,一些功能比较明确的mi RNAs有望成为PCOS疾病诊断和预后评估的生物学标志物,为PCOS的治疗提供新思路。     

腹腔镜与开腹输卵管吻合术后妊娠率的比较

目的探讨腹腔镜输卵管吻合术治疗输卵管绝育术后或单纯输卵管堵塞不孕症的妊娠结局。方法2006年1月-2013年8月,48例要求输卵管吻合术治疗的输卵管绝育术后或单纯输卵管峡部堵塞性不孕症患者,按患者就诊顺序依次进入腹腔镜组和开腹组（各24例）,2组均为20例绝育术后,4例不孕症。对2组吻合成功率及术后妊娠情况等进行比较。结果所有手术均顺利完成,术中双侧输卵管均通畅。术后2年妊娠率腹腔镜组高于开腹组[87．5％（21／24）vs．62．5％（15／24）,x2=4．000,P=0．046]。结论腹腔镜输卵管吻合术的手术成功率与开腹手术相当,而术后妊娠率高于开腹组,且手术创伤小,有广阔的应用空间。