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Vijay Juneja Sudarsan Mukhopadhyay Harry Marks Tim B. Mohr Alex Warning Ashim Datta 《Food and Bioprocess Technology》2014,7(2):437-446
The effects and interactions of heating temperature (60 °C to 73.9 °C), salt (0.0 % to 4.5 %?w/v), sodium pyrophosphate (0.0 % to 0.5 %?w/v), and sodium lactate (0.0 % to 4.5 %?w/v) on the heat resistance of a five-strain mixture of Listeria monocytogenes in 75 % lean ground beef were examined. Meat samples in sterile filtered stomacher bags were heated in a temperature controlled waterbath to determine thermal death times. The recovery medium was tryptic soy agar supplemented with 0.6 % yeast extract and 1 % sodium pyruvate. Weibull survival functions were employed to model the primary survival curves. Then, survival curve-specific estimated parameter values obtained from the Weibull model were used for determining a secondary model. The results indicate that temperature and salt have a large impact on the inactivation kinetics of L. monocytogenes, while sodium lactate (NaL) has an impact in the presence of salt. The model presented in this paper for predicting inactivation of L. monocytogenes can be used as an aid in designing lethality treatments meant to control the presence of this pathogen in ready-to-eat products. 相似文献
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Tim Baker 《国际生产研究杂志》2013,51(7):1767-1779
We develop a new, flexible independent demand forecasting-optimisation algorithm, and apply it to nine difficult-to-manage maintenance and repair products at the AREVA nuclear fuel rod manufacturing facility. The algorithm results in a 27% reduction in inventory holding and ordering costs relative to AREVA's baseline ERP method. This is in addition to improving the line item fill rates from 96 to 98%. This new algorithm is more flexible than the baseline method in that (1) our forecast error distribution is not assumed to be normal—we automatically find the best-fitting distribution from a large family of distributions, (2) we jointly optimise the order quantity and reorder point by using an optimisation routine that is embedded in a simulation methodology. Our algorithm can therefore handle a non-stationary demand process during the planning horizon, and (3) we dynamically select the best time series forecaster for demand based on the most recent history. This flexibility drove the performance improvements. Our algorithm can be easily adapted to any independent demand situation across any industry's supply chain. 相似文献
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Workplace violence is a leading form of occupational injury and fatality, but has received little attention from the ergonomics research community. The paper reports findings from the 2012 New Zealand Workplace Violence Survey, and examines the workplace violence experience of 86 New Zealand organisations and the perceptions of occupational health and safety professionals from a systems perspective. Over 50% of respondents reported violence cases in their organisation, with perpetrators evenly split between co-workers and external sources such as patients. Highest reported levels of violence were observed for agriculture, forestry and construction sectors. Highest risk factor ratings were reported for interpersonal and organisational factors, notably interpersonal communication, time pressure and workloads, with lowest ratings for environmental factors. A range of violence prevention measures were reported, although most organisations relied on single control measures, suggesting unmanaged violence risks were common among the sample. 相似文献
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Giuliano Fontanella Daniele Basciotti Florian Dubisch Florian Judex Anita Preisler Christian Hettfleisch Vladimir Vukovic Tim Selke 《Building Simulation》2012,5(3):293-300
Recent advancements in the domain of modeling physical processes offer opportunities to use equation based modeling environments, such as Modelica, for the simulation of building heating, ventilation, and air-conditioning (HVAC) systems. The current work demonstrates Modelica capabilities in a case study of real building solar thermal system simulation. The simulated system is part of an innovative ENERGYbase building, designed according to the so called Passivhaus standard. Model calibration and validation procedure is developed to include optimization based parametric adjustments of component models using the monitoring data during a single week. The calibrated system adequately reproduces half a year of real system operation. Future work will concentrate on application of the developed calibration and validation methodology in the whole year overall building energy simulation. 相似文献
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Cora-Costanze Sommerey Tim L. WilliamsIan McCrone Aran Ruiz-FerrerasDan Freeman Joy Archer 《Journal of dairy science》2014
Thromboelastography is a whole blood-based coagulation assay that can be used to investigate hypocoagulability and hypercoagulability, as seen with thromboembolic diseases and disseminated intravascular coagulation. Numerous coagulopathies due to different causes are reported in cows. The objective was to establish reference intervals for thromboelastography using the TEG 5000 (Haemonetics GmbH, Munich, Germany) with citrated whole blood samples and kaolin activation in dairy cows and to investigate possible thromboelastographic changes between cows in different lactation periods. An additional objective was to test the stability of samples for up to 100 h. Sixty blood samples from healthy Holstein-Friesian cows were examined. The samples were allocated to 3 different lactation groups (≤30 d postcalving, 31–99 d postcalving, ≥100 d postcalving). Thromboelastography was performed by using the TEG 5000 analyzer with citrated whole blood samples with kaolin activation. The calculated reference intervals were as follows: reaction time = 2.2 to 6.2 min, coagulation time = 0.8 to 2.0 min, angle α = 58.2 to 81.8°, maximum amplitude = 64.3 to 89.2 mm, and clot rigidity = 9.2 to 41.2 dyn/cm2. The 3 different lactation groups showed no significant differences in TEG parameters. No significant difference was seen in samples stored for up to 48 h at room temperature, which indicates that delays in processing samples, such as those arising during transit, are not an issue. 相似文献