LP-BM5 virus causes changes in lactic dehydrogenase and oxygen radical production in splenocytes of C57BL/6J mice

The LP-BM5 murine leukemia virus causes acquired immunodeficiency syndrome in C57BL/6J mice (MAIDS), similar to that of AIDS in humans. The objective of this study was to determine the effect of LP-BM5 viral infection on cellular activation and membrane integrity of splenocytes. Oxidative burst in splenocytes in response to exposure to PMA (20 microg/ml) was significantly higher (p<.02) in infected than in control mice at two weeks post-infection using luminol-enhanced chemiluminescence. By 13 weeks post-infection superoxide anion production in infected mice was significantly lower when compared to controls coinciding with decreased proliferative response to mitogens. The extent of cell membrane damage as indicated by lactic dehydrogenase (LDH) activity in serum was significantly higher in infected than in control mice (p<.001). The results from this study suggests that LP-BM5 virus causes an initial stimulation of cellular activity followed by a decreased cell activation characterized by decreased proliferation of splenocytes and decreased oxygen radical production. Decreased cell membrane integrity indicated by increased LDH activity may partly be responsible for these changes.     

Surface characterization of sprayed CuGa x In1−x Se2 layers

Small-area polycrystalline CuGa _x In_1–x Se₂-based solar cells produced in the laboratory have been reported with efficiencies up to 18.8%. This success at achieving high-efficiency devices has stimulated a parallel research effort to produce large-area modules based on the use of CuGa _x In_1–x Se₂ with reduced cost of production. One method that has potential to achieve these objectives is chemical spray pyrolysis. Preliminary studies have resulted in devices with efficiencies of 4–5%. Further improvements toward implementing higher-efficiency devices are expected to result from a better understanding of the physical and chemical properties of the chalcopyrite layers produced. In this work we have investigated, for the first time, the properties of these layers using X-ray photoelectron spectroscopy (XPS) to identify the secondary phases and residual impurities present. The layers studied were for In/Ga mole ratios of x=0, 0.2, 0.4, 0.6, 0.8, and 1.0 in CuGa _x In_1–x Se₂. The layers were also profiled by sputter etching away the surface of the layers and repeating the XPS measurements. The effects of annealing the layers in air, vacuum, and selenium vapor were also investigated.     

Analysis of slots in nonradiating dielectric waveguide using the modal expansion method

A modal expansion method is used with the reciprocity and Poynting theorems to derive the admittance of inclined slots cut in the metal wall of a nonradiating dielectric (NRD) waveguide. Theoretical values of normalised conductance and susceptance are compared with previously reported experimental results and are found to be in good agreement.<>     

Comparative study of crystallization processes in Sb2Te3 films using laser and thermal annealing techniques

Adherent and pin-hole free amorphous Sb₂Te₃ thin films have been obtained by vacuum evaporation at substrate temperatures ≤25 °C. The films have been crystallized by thermal and laser annealing, and the crystallization processes monitored as a function of annealing temperature and laser scan speed. A comparative study of topography reveals disk-shaped crystallized areas in thermal crystallization and dendrite growth in the laser induced process. The crystallized films in both cases contain a single Sb₂Te₃ phase. Activation energy of 2 eV for crystallization, determined using differential scanning calorimetery indicates good room temperature stability of the amorphous states.     

Graph‐Theory Approach to Eigenvalue Problem of Large Space Structures

The dynamic analysis and control system design of large space structures involve the solution of the large‐dimensional generalized matrix eigenvalue problem. The computational effort involved is proportional to the third power of the dimension of the matrices involved. To minimize the computational time a graph‐theory approach to reduce a matrix to lower‐ordered submatrices is proposed. The matrix‐reduction algorithm uses the Boolean matrices corresponding to the original numerical matrices and, thus, the computational effort to reduce the original matrix is nominal. The computational savings directly depend upon the number of submatrices into which the original matrix is reduced. A free‐free square plate is considered as an example to illustrate the technique. In this example a matrix of 16th order is reduced to three scalars corresponding to three rigid‐body modes, and three matrices of order three and one matrix of order four.     

Mixed convection boundary layer flow of a micropolar fluid along vertical cylinders and needles

An analysis is presented to investigate the effects of buoyancy and curvature on convection along vertical cylinders and needles placed in a micropolar fluid. The governing equations for momentum, angular momentum and energy are solved numerically by finite difference scheme. The heat transfer results are presented for a range of values of the buoyancy parameters, the curvature parameter and the material parameters of the fluid. The effect of the microrotation boundary conditions on heat transfer is discussed.     

Finite data performance analysis of MVDR beamformer with andwithout spatial smoothing

The finite-data performance of a minimum-variance distortionless response (MVDR) beamformer is analyzed with and without spatial smoothing, using first-order perturbation theory. In particular, expressions are developed for the mean values of the power gain in any direction of interest, the output power, and the norm of the weight-error vector, as a function of the number of snapshots and the number of smoothing steps. It is shown that, in general, the smoothing, in addition to decorrelating the sources, can alleviate the effects of finite-data perturbations. The above expressions are reduced to the case in which no spatial smoothing is used. These expressions are valid for an arbitrary array and for arbitrarily correlated signals. For this case, an expression for the variance of the power gain is also developed. For a single interference case it is shown explicitly how the SNR, spacing of the interference from the desired signal and the correlation between them influence the beamformer performance. Simulations verify the usefulness of the theoretical expressions     

Nutritional aspects of colon cancer

During the last decade, a substantial amount of progress has been made in the understanding of the relationship between the dietary constituents and the development of colon cancer in man. The information base is sufficiently convincing with respect to an enhancing effect as a function of total fat intake and a protective effect of certain dietary fibers in colon cancer. The populations with high incidence of colon cancer are characterized by consumption of high-dietary fat which may be a risk factor in the absence of factors that are protective, such as use of whole-grain cereals, high fibrous foods and vegetables mainly of cruciferous type. Application of the findings made thus far in colon cancer research for the general public is, therefore, to have a far-reaching impact on the major premature, killing diseases in the western world.