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101.
An efficient simulation of thermal and mechanical models involved in thermosetting composites forming needs to overcome some numerical difficulties related to: (i) the multi-scale behaviour; (ii) the complex geometries involved needing too many degrees of freedom; (iii) the large time intervals where the solution has to be computed; (iv) the non-linearity of the involved evolution equations; (v) the numerous couplings… In this work, an efficient strategy based on a separated representation is proposed. This method enables to avoid the use of an incremental strategy and can lead to impressive computing time savings especially when the model involves fine meshes and very small time steps. The local non-linear chemical kinetics and its coupling with the global heat balance equation are naturally introduced in the separated representation algorithm. Moreover, the dependence of the thermal conductivity and the specific heat on the temperature and on the reaction advancement degree are also taken into account. Knowing the history of the temperature field, the separated representation is again used to solve the thermo-mechanical problem in order to determine the residual stresses.  相似文献   
102.
Platelet adhesion and activation rates are frequently used to assess the thrombogenicity of biomaterials, which is a crucial step for the development of blood-contacting devices. Until now, electron and confocal microscopes have been used to investigate platelet activation but they failed to characterize this activation quantitatively and in real time. In order to overcome these limitations, quartz crystal microbalance with dissipation (QCM-D) was employed and an explicit time scale introduced in the dissipation versus frequency plots (Df–t) provided us with quantitative data at different stages of platelet activation. The QCM-D chips were coated with thrombogenic and non-thrombogenic model proteins to develop the methodology, further extended to investigate polymer thrombogenicity. Electron microscopy and immunofluorescence labelling were used to validate the QCM-D data and confirmed the relevance of Df–t plots to discriminate the activation rate among protein-modified surfaces. The responses showed the predominant role of surface hydrophobicity and roughness towards platelet activation and thereby towards polymer thrombogenicity. Modelling experimental data obtained with QCM-D with a Matlab code allowed us to define the rate at which mass change occurs (A/B), to obtain an A/B value for each polymer and correlate this value with polymer thrombogenicity.  相似文献   
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Several carbon‐black filled styrene‐butadiene rubbers are subjected to monotonic uniaxial tension tests in order to investigate the effects of the amount of fillers and of the crosslink density on their mechanical properties. The Young modulus, the volume changes associated with material damage and the stretch to failure are extracted and discussed. Results compare well to the literature results when exist and quantitative analysis are proposed when possible. Results show that filled rubbers are not incompressible when submitted to uniaxial tension tests and their volume changes are strongly dependent of the amount of fillers but are unaffected by the crosslink density. The latter shows strong impact on the filled rubbers stretch to failure but more interestingly this impact is comparable to what is encountered in unfilled rubbers. The stretch to failure is improved by the addition of fillers with an optimum for material filled around 30 phr. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013  相似文献   
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Contaminated shellfish have been implicated in gastroenteritis outbreaks in different countries. As no regulation has been set up yet regarding viral contamination of food, very few data are available on the prevalence of contaminated products on the market. This study presents data obtained from oysters collected on the French market in one producing area over a 16 month period of time. Noroviruses were detected in 9% of samples with a seasonal impact and influence of climatic events. Contamination levels were low and, surprisingly, oysters sampled directly from the producer were found to have less contamination than oysters from supermarkets.  相似文献   
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A first order correction is proposed taking into account both interface elasticity and transverse anticlastic curvature of flexible substrate(s) in the DCB (and related tests). Adherends are represented by Kirchhoff–Love plates, and the interface by a Winkler-type elastic foundation. Two functions are introduced, representing evolution of beam deflection along the sample midline and anticlastic curvature along the plate. A method of virtual work is used to find the associated equilibrium equation. The two-dimensional sample deformation is determined semi-analytically. Sample rigidity and energy release rate are computed for various geometrical configurations and compared to more common models.  相似文献   
108.
This paper reports the first stage of work being undertaken to understand the factors that have impacted on the current state of food safety in the UK food manufacturing sector. The paper first explores developments in international food safety regulation in general and in particular, the UK. Using a survey and case study methodology, the paper examines the response of food manufacturing enterprises to food safety regulation, and uses statistical techniques to investigate the effects of enterprise size on the drivers for, benefits of, and challenges to compliance. Further, the factors that influence the successful implementation of an integrated food safety management system are also examined. The results show a great deal of both statutory and private regulation that has incentivised enterprises. In response, enterprises have implemented integrated food safety management systems to proactively deal with the risks associated with food safety, however, enterprises claim that statutory regulations are biased towards consumers, without adequate impact assessments on all stakeholders within the chain, and hence causing industry to incur significant costs that could otherwise be avoided. Even though compliance with food safety regulation is burdensome, the cost of non-compliance will also be significant to enterprises. The findings also show that there is no significant effect of size of enterprise on the drivers, benefits and challenges to compliance with food safety regulation.  相似文献   
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The learning of complex relationships can be decomposed into several neural networks. The modular organization is determined by prior knowledge of the problem that permits to split the processing into tasks of small dimensionality. The sub-tasks can be implemented with neural networks, although the learning examples cannot be used anymore to supervise directly each of the networks. This article addresses the problem of learning in a modular context, developing in particular additive compositions. A simple rule allows defining efficient training, and combining, for example, several Supervised-SOM networks. This technique is important because it introduces interesting generalizations in many modular compositions, permitting data fusion or sequential combinations of neural networks. This revised version was published online in August 2006 with corrections to the Cover Date.  相似文献   
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