Biting force and physical fitness in athletes

The maximum biting force in 82 male athletes and 12 male subjects without any particular athletic activity (nonathletes) were measured in order to evaluate the relationship between biting force and physical fitness in athletes. The results obtained were as follows. 1. The maximum biting force in athletes (50.8 +/- 17.4kg) were significantly (p < 0.01) higher than that in the nonathletes (28.1 +/- 9.1kg). The maximum biting forces in the men who belonged to the rugby or judo clubs were predominantly higher than in other subjects. 2. In men who masticated on the left side of the mouth, the habitual (i. e., left) biting force was significantly higher than the nonhabitual (i. e., right) biting force. In men who masticated on the right side of the mouth, the habitual (i. e., right) biting force was also higher than the nonhabitual (i. e., left) biting force, but was not significantly so. 3. There was a significant positive correlation between the biting force and grip strength and back strength in athletes. In athletes, there was a significant correlation between biting force and the numbers of chin-ups, the numbers for the side-step tests and the time for 50m running.     

Polyhedral assembly of a membrane protein in its three-dimensional crystal

A novel ordered assemblage of bacteriorhodopsin, a transmembrane protein functioning as a light-driven proton pump, is found in its three-dimensional crystal. Atomic force microscope images of the crystal surface reveal that spherical protein clusters with a diameter of approximately 50 nm are hexagonally close-packed. Electron micrographs of mechanically disintegrated crystals show that the inside of the protein cluster is filled with the mother liquor. The crystal is made up of hollow protein clusters. When disintegrated crystals are illuminated in the presence of a lipophilic anion, a significant alkalization of the external medium occurs. This result indicates that the protein cluster contains native lipids and that the cytoplasmic side of the protein faces the external medium. X-ray diffraction patterns and the observed diameter of the spherical shell suggest that approximately 200 bacteriorhodopsin trimers are aligned on a polyhedral surface lattice. Another remarkable feature of the spherical assemblies of bacteriorhodopsin is that they fuse with each other at low ionic strength and occasionally form a tubular or doughnut-like structure. The concept of membrane protein polymorphism is introduced on the basis of these observations, and it is used to describe the dynamic structure of some other biological membranes.     

The novel compound NO-1886 increases lipoprotein lipase activity with resulting elevation of high density lipoprotein cholesterol, and long-term administration inhibits atherogenesis in the coronary arteries of rats with experimental atherosclerosis

We have discovered a novel compound, NO-1886, which possesses a powerful lipoprotein lipase (LPL) activity-increasing action. Administration of NO-1886 increased LPL activity in the postheparin plasma, adipose tissue, and myocardium of rats, and produced a reduction in plasma triglyceride levels with concomitant elevation of HDL cholesterol levels. Administration of NO-1886 increased LPL enzyme mass in postheparin plasma and mRNA activity in epididymal adipose tissue, and it was concluded that the mode of action of this compound is stimulation of tissue LPL synthesis. We also conducted long-term studies to assess the impact of increases in LPL activity and HDL levels on the development of atherosclerotic lesions in rats. Administration of NO-1886 for as long as 90 d significantly decreased the degree of atherosclerotic changes in the coronary arteries of vitamin D2-treated, cholesterol-fed rats. Statistical analysis indicated that increased concentration of HDL is the factor contributing mostly to the prevention of coronary artery sclerosis. In summary, the results of our study indicate that compound NO-1886 increases LPL activity, causing an elevation in HDL levels, and that long-term administration of NO-1886 to rats with experimental atherosclerosis provides significant protection against the development of coronary artery lesions.     

Perpendicular magnetic recording

This paper describes the recent studies for the magnetic head, the medium and the recording properties on a new perpendicular magnetic recording system. The complemental features between the perpendicular and the longitudinal recording are discussed to establish an efficient magnetic recording system. Superior response in the amplitude and the peak shift characteristics for a digital signal proves that the perpendicular magnetization mode is basically free from the recording demagnetization in high densities and the maximum density has been limited merely by the resolution of the reproducing head. Significant improvement for the recording and the reproducing sensitivities of a perpendicular head has been made by using a composite anisotropy medium composed by double layers of Fe-Ni and Co-Cr thin films.     

Sensorless control of ultrahigh-speed PM brushless motor using PLL and third harmonic back EMF

Application-specific integrated circuit (ASIC) ML4425 is often used for sensorless control of permanent-magnet (PM) brushless direct current (BLDC) motor drives. It integrates the terminal voltage of the unenergized winding that contains the back electromotive force (EMF) information and uses a phase-locked loop (PLL) to determine the proper commutation sequence for the BLDC motor. However, even without pulsewidth modulation, the terminal voltage is distorted by voltage pulses due to the freewheel diode conduction. The pulses, which appear very wide in an ultrahigh-speed (120 kr/min) drive, are also integrated by the ASIC. Consequently, the motor commutation is significantly retarded, and the drive performance is deteriorated. In this paper, it is proposed that the ASIC should integrate the third harmonic back EMF instead of the terminal voltage, such that the commutation retarding is largely reduced and the motor performance is improved. Basic principle and implementation of the new ASIC-based sensorless controller will be presented, and experimental results will be given to verify the control strategy. On the other hand, phase delay in the motor currents arises due to the influence of winding inductance, reducing the drive performance. Therefore, a novel circuit with discrete components is proposed. It also uses the integration of third harmonic back EMF and the PLL technique and provides controllable advanced commutation to the BLDC motor.     

Receiver sensitivity temperature dependence of small detectable area Hi-Lo germanium avalanche photodiode

Optical receiver sensitivity temperature dependence is measured in different detectable area (80, 30 ?m-diameter) Hi-Lo Ge APD modules at 450 Mbit/s bit rates. A 30 ?m-diameter device has a little power penalty against temperature increase compared with an 80 ?m-diameter device, with 2.4 dB receiver sensitivity improvement at 45°C.     

The concept and implementation of skeletal plans

A new method for automated planning, refinement of skeletal plans, has been developed for the problem of experiment design in the domain of molecular biology. The method resulted from a study of the problem-solving behavior of scientists which showed that design usually consisted of look-up of abstracted plans followed by hierarchical plan-step refinement. The skeletal plan method has been implemented through two generations of problem-solving systems, the second generation involving a synthesis with the metaplanning approach of Stefik.     

Cases of multiple ventricular septal defects

We had 4 cases with multiple ventricular septal defects (VSDs) in complexed congenital heart disease. One of four had two separate VSDs detected by two dimensional echocardiography before operation. Second of four had additional infundibular muscular VSD which was detected by echocardiography in the intensive care unit (ICU) after patch closure of a perimembranous VSD. The third case had two additional VSDs of inlet muscular and subaortic septum detected by transesophageal and direct echocardiography during reoperation, beside a subpulmonary VSD which was originally diagnosed before Jatene operation for double outlet right ventricle. The fourth case had multiple trabecular muscular VSDs diagnosed by postoperative angiography soon after Rastelli operation. Since these additional multiple VSDs compromise the postoperative hemodynamics if those are unrecognized, it is indispensable to detect all VSDs before operation, using transthoracic and transesophageal echocardiography.     

Comparison of reproduction performance of a single pole head and a ring head

The reproduction pulse amplitude of a single pole head from double-layer perpendicular media has been analyzed. We derived an analytic expression to relate the pulse amplitude to the head and medium parameters. Experimental data are also presented to verify the calculated results. The reproduction performances of a single pole head and a ring head are theoretically compared and found to be comparable when both are normalized to the same head inductance.