A Low‐Toxic Multifunctional Nanoplatform Based on Cu9S5@mSiO2 Core‐Shell Nanocomposites: Combining Photothermal‐ and Chemotherapies with Infrared Thermal Imaging for Cancer Treatment

Copper chalcogenides have been demonstrated to be a promising photothermal agent due to their high photothermal conversion efficiency, synthetic simplicity, and low cost. However, the hydrophobic and less biocompatible characteristics associated with their synthetic processes hamper widely biological applications. An alternative strategy for improving hydrophilicity and biocompatibility is to coat the copper chalcogenide nanomaterials with silica shell. Herein, the rational preparation design results in successful coating mesoporous silica (mSiO₂) on as‐synthesized Cu₉S₅ nanocrystals, forming Cu₉S₅@mSiO₂‐PEG core‐shell nanostructures. As‐prepared Cu₉S₅@mSiO₂‐PEG core‐shell nanostructures show low cytotoxicity and excellent blood compatibility, and are effectively employed for photothermal ablation of cancer cells and infrared thermal imaging. Moreover, anticancer drug of doxorubicin (DOX)‐loaded Cu₉S₅@mSiO₂‐PEG core‐shell nanostructures show pH sensitive release profile and are therefore beneficial to delivery of DOX into cancer cells for chemotherapy. Importantly, the combination of photothermal‐ and chemotherapies demonstrates better effects of therapy on cancer treatment than individual therapy approaches in vitro and in vivo.     

LIGA技术制作Fresnel波带片的研究

简要介绍了利用ＬＩＧＡ技术中同步辐射光刻、微电铸技术制作α粒子编码成像波带片的研究,讨论了编码波带片的结构和影响波带片的平面和层析分辨率的参数。根据实验要求设计和研制了一种α粒子编码成像波带片。     

In Situ Formation of Copper‐Based Hosts Embedded within 3D N‐Doped Hierarchically Porous Carbon Networks for Ultralong Cycle Lithium–Sulfur Batteries

Lithium–sulfur (Li–S) batteries are promising energy storage systems due to their large theoretical energy density of 2600 Wh kg^?1 and cost effectiveness. However, the severe shuttle effect of soluble lithium polysulfide intermediates (LiPSs) and sluggish redox kinetics during the cycling process cause low sulfur utilization, rapid capacity fading, and a low coulombic efficiency. Here, a 3D copper, nitrogen co‐doped hierarchically porous graphitic carbon network developed through a freeze‐drying method (denoted as 3D Cu@NC‐F) is prepared, and it possesses strong chemical absorption and electrocatalytic conversion activity for LiPSs as highly efficient sulfur host materials in Li–S batteries. The porous carbon network consisting of 2D cross‐linked ultrathin carbon nanosheets provides void space to accommodate volumetric expansion upon lithiation, while the Cu, N‐doping effect plays a critical role for the confinement of polysulfides through chemical bonding. In addition, after sulfuration of Cu@NC‐F network, the in situ grown copper sulfide (Cu_xS) embedded within Cu_xS@NC/S‐F composite catalyzes LiPSs conversion during reversible cycling, resulting in low polarization and fast redox reaction kinetics. At a current density of 0.1 C, the Cu_xS@NC/S‐F composites' electrode exhibits an initial capacity of 1432 mAh g^?1 and maintains 1169 mAh g^?1 after 120 cycles, with a coulombic efficiency of nearly 100%.     

LD泵浦OF耦合NYAB自倍频激光器的初步研究

研制出国内第一台LD泵浦OF耦合NYAB自倍频激光器,产生0.531μm的线偏振绿色激光。基横模运转,阈值泵浦功率为14mW,输出功率达3.6mW,斜效率达3％,偏振度大于99.8％。     

同步数字体系中155Mbit/s净荷的误码测试

本文基于光纤传输同步数字体系(S D H)系统的开发背景,较为详细地总结了155Mbit/s速率下的净荷误码测试机理.最后给出了净荷的误码测试方法以及误码测试系统的信号流程.     

X80钢级1422mm大口径管道断裂控制技术

在中俄东线天然气管道工程中采用高钢级(X80钢级)、大口径(外径为1 422 mm)的管道进行高压输送(压力为12MPa)可以有效增加天然气输送量,满足我国能源战略的需要。然而随着钢级、输送压力、管径及设计系数的不断提高,管道的延性断裂成为断裂的主要方式,止裂控制便成为研究的重点。为此,对止裂韧性计算的主要方法 Battelle双曲线(BTC)方法以及断裂阻力曲线和减压波曲线进行了深入研究,明确了BTC方法的原理及其适用范围,同时分析了BTC方法应用于高强度、高韧性管线钢时所存在的问题,给出了目前国际上针对BTC计算结果常用的修正方法。回顾了俄罗斯Bovanenkovo-Ukhta外径为1 422 mm X80管道断裂的控制方案,针对中俄东线管道的设计参数,对BTC计算结果进行了修正,进而制订出符合中俄东线天然气管道安全要求的止裂韧性值(245 J)。     

长庆油田一体化水井带压装备研究与开发

分体式带压作业机存在搬家车次较多、作业过程中人员相互配合不便、受井场大小限制以及部分注水井无法进行作业等问题。为此,结合长庆油区特点研究开发了新型一体化水井带压作业机。该带压作业机将行走系统、提升系统与液控系统的动力源合三为一,具有节约能源、搬迁快捷、安装方便、机动灵活等特点;修井车滚筒刹车系统采用液压盘式刹车,使设备的提升、制动系统安全性能大大提高。一体化水井带压装备实现了分散设备系统的整合、集成和一机多能,在21 MPa范围内注水井维护作业不需要放喷泄压,并克服了现有装备的缺点和局限性,提高了施工作业效率,具有较高的推广价值。     

套管井自然伽马能谱测井资料的应用分析

自然伽马能谱测井是一种新的测井方法。该文主要针对胜利油田的多个油区的套管井自然伽马能谱测井资料的应用实例进行了分析，指出它在开发过程中对研究管外窜槽、注水层的吸水量、判断水淹层和划分水淹级别、划分储集层和判断储集层性质、划分油层中的泥岩夹层、确定泥质含量及粘土类型等方面的重要作用。在综合其它测井方法后，能对研究储层变化、寻找剩余油分布等提供重要的手段。     

油井腐蚀监测技术与防腐蚀

中原油田油井腐蚀严重,据估算,每年因腐蚀报废的管、杆、泵等直接经济损失就达4000多万元;因腐蚀导致的油井停产、作业等造成的损失,更是难以估计。为解决油井腐蚀难题,对中原油田采油一厂油井腐蚀现状进行了分析,对油井腐蚀监测技术和监测结论进行了介绍,对造成油井腐蚀的因素进行了详细分析,并提出了一系列油井防腐蚀对策。     

硼，氮共掺碳纳米管的第一性原理研究

小管径单壁碳纳米管因为曲率效应和局部效应的影响,有着不同的电学性能。传统的密度泛函计算并不能完全处理这些影响因素,但是杂化泛函计算却可以。我们通过HSE杂化泛函计算研究了（2,3）碳纳米管共掺杂不同浓度的氮,硼原子,发现了能隙和一些其他性质均随着掺杂成分的改变而发生振荡变化。我们的研究阐明了对小管径纳米管性质的认识。这对设计新型纳米电子设备有潜在作用。