首页 | 官方网站   微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   26231篇
  免费   287篇
  国内免费   14篇
文化教育   26532篇
  2021年   252篇
  2020年   359篇
  2019年   541篇
  2018年   778篇
  2017年   759篇
  2016年   820篇
  2015年   511篇
  2014年   578篇
  2013年   4302篇
  2012年   621篇
  2011年   694篇
  2010年   477篇
  2009年   461篇
  2008年   533篇
  2007年   492篇
  2006年   457篇
  2005年   992篇
  2004年   833篇
  2003年   593篇
  2002年   450篇
  2001年   519篇
  2000年   538篇
  1999年   457篇
  1998年   258篇
  1997年   251篇
  1996年   310篇
  1995年   247篇
  1994年   258篇
  1993年   221篇
  1992年   350篇
  1991年   367篇
  1990年   340篇
  1989年   365篇
  1988年   337篇
  1987年   329篇
  1986年   325篇
  1985年   370篇
  1984年   292篇
  1983年   303篇
  1982年   239篇
  1981年   246篇
  1980年   259篇
  1979年   349篇
  1978年   258篇
  1977年   238篇
  1976年   201篇
  1975年   181篇
  1974年   182篇
  1973年   176篇
  1971年   174篇
排序方式: 共有10000条查询结果,搜索用时 8 毫秒
81.
OBJECTIVES: Medical Library Association (MLA) members were surveyed to gather background about the current state of expert searching in institutions. The survey results were intended to guide the recommendations of the Task Force on Expert Searching for promoting the importance of expert searching and implementing those recommendations. METHODS: MLA members were surveyed, and data obtained from the survey were compiled and analyzed to answer three general questions: what is the perceived value of searching skills to the institution, how do health sciences librarians maintain and improve their searching skills, and how are searching services promoted and/or mandated in the institution. RESULTS: There were 256 responses to the survey. Over 95% of the respondents saw their expert-searching skills were of value to their institutions, primarily through performing mediated searches and search consultations. Over 83% of the respondents believed that their searching skills had improved over the past 10 years. Most indicated that continued training was very important in maintaining and improving their skills. Respondents promoted searching services most frequently through orientations, brochures, and the libraries' Web pages. No respondent's institution mandated expert searching. Less than 2% of respondents' institutions had best practice guidelines related to expert searching, and only about 8% had guidelines or policies that identified situations where expert searching was recommended. CONCLUSIONS: The survey supports the belief that health sciences librarians still play a valuable role in searching, particularly in answering questions about treatment options and in providing education. It also highlights the need for more expert searching courses. There has been minimal discussion about the perceived need for expert-searching guidelines in the institutions represented by survey respondents.  相似文献   
82.
In 2008 Meier and Conkling first tested Google Scholar's coverage of the engineering literature against citations gathered from the Compendex database. Since that time, other studies have used the same methodology and found improvement in Google Scholar's coverage. This study uses engineering dissertations from Proquest Dissertations & Theses to create a data set of citations for the comparison of fee-based databases, Compendex and Scopus, against Google Scholar. From 1950 to 2017 Google Scholar outperformed both Compendex and Scopus in discoverability of citations in nine engineering subjects. These results have implications for collection management and information literacy program planning for librarians.  相似文献   
83.
ABSTRACT

The career path and significant professional accomplishments of librarian Valerie Bross (1954–2016) are described in this article. The awards and recognition she received are recounted and the influence of outside activities on her career is assessed. An attempt is made to capture what she was like as a professional, as well as what her unique characteristics were. A bibliography of her writings and a photograph are included.  相似文献   
84.
Inconsistency is often considered an indication of deceit. The conceptualization of consistency used in deception research, however, has not made a clear distinction between two concepts long differentiated by philosophers: coherence and correspondence. The existing literature suggests that coherence is not generally useful for deception detection. Correspondence, however, appears to be quite useful. The present research developed a model of how correspondence is utilized to make judgments, and this article reports on four studies designed to elaborate on the model. The results suggest that judges attend strongly to correspondence and that they do so in an additive fashion. As noncorrespondent information accumulates, an increasingly smaller proportion of judges make truthful assessments of guilty suspects. This work provides a basic framework for examining how information is utilized to make deception judgments and forms the correspondence and coherence module of truth-default theory.  相似文献   
85.
86.
87.
88.
BackgroundConsidering the potential cumulative effects of repetitive head impact (HI) exposure, we need sensitive biomarkers to track short- and long-term effects. Circulating small extracellular vesicles (sEVs) (<200 nm) traffic biological molecules throughout the body and may have diagnostic value as biomarkers for disease. The purpose of this study was to identify the microRNA (miRNA) profile in circulating sEVs derived from human plasma following repetitive HI exposure.MethodsHealthy adult (aged 18–35 years) soccer players were randomly assigned to one of 3 groups: the HI group performed 10 standing headers, the leg impact group performed 10 soccer ball trapping maneuvers over 10 min, and the control group did not participate in any soccer drills. Plasma was collected before testing and 24 h afterward, and sEVs were isolated and characterized via nanoparticle tracking analysis. Next-generation sequencing was utilized to identify candidate miRNAs isolated from sEVs, and candidate microRNAs were analyzed via quantitative polymerase chain reaction. In silico target prediction was performed using TargetScan (Version 7.0; targetscan.org) and miRWalk (http://mirwalk.umm.uni-heidelberg.de/) programs, and target validation was performed using luciferase reporter vectors with a miR-7844-5p mimic in human embryonic kidney (HEK) 293T/17 cells.ResultsPlasma sEV concentration and size were not affected across time and group following repetitive HI exposure. After 24 h, the HI read count from next-generation sequencing showed a 4-fold or greater increase in miR-92b-5p, miR-423-5p, and miR-24-3p and a 3-fold or greater decrease in miR-7844-5p, miR-144-5p, miR-221-5p, and miR-22-3p. Analysis of quantitative polymerase chain reaction revealed that leg impact did not alter the candidate miRNA levels. To our knowledge, miR-7844-5p is a previously unknown miRNA. We identified 8 miR-7844-5p mRNA targets: protein phosphatase 1 regulatory inhibitor subunit 1B (PPP1R1B), LIM and senescent cell antigen-like domains 1 (LIMS1), autophagy-related 12 (ATG12), microtubule-associated protein 1 light chain 3 beta (MAP1LC3B), integrin subunit alpha-1 (ITGA1), mitogen-activated protein kinase 1 (MAPK1), glycogen synthase kinase 3β (GSK3β), and mitogen-activated protein kinase 8 (MAPK8).ConclusionCollectively, these data indicate repetitive HI exposure alters plasma sEV miRNA content, but not sEV size or number. Furthermore, for the first time we demonstrate that previously unknown miR-7844-5p targets mRNAs known to be involved in mitochondrial apoptosis, autophagy regulation, mood disorders, and neurodegenerative disease.  相似文献   
89.
90.
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司    京ICP备09084417号-23

京公网安备 11010802026262号