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31.
Wu Jue吴珏Department of Anesthesiologlj Shanghai Medical University ShanghaiXie Fu-sheng谢福生Teaching Hospital Guangzhou College of Traditional Chinese Medicine Guangzhou 《中华医学杂志(英文版)》1987,100(3):173-176
Dimethyll-curine dimethochloride was obtained
by methylating the l-curine which was isolated from
plants belonging to Genesia Cyclea widely distributed
in Hainan Island, South China. It is a non-depolariz-
ing post neuromuscular junctional blocker acting
upon N2 receptor. Its chemical structural formula,
physical properties, pharmacological actions and acute
or chronic toxicities have been thoroughly studied. Its
biological activities varied a great deal in different
experimental animals but their clinical potency is
uniform. Its activity is 51.8% as those of d-tubocura
rine. Clinically, 1,449 cases, male and female, aged
and young, were studied. Among them 422 were
employed for endotracheal intubation, 468 for muscu
Iar relaxation and 559 for both. Operation varied,
including intracraneal, intra-abdominal and open
heart surgery. Different kinds of anesthetics and
adjuvants were used in association. I.V. dosage of
0.4-0.5 mg/kg or more was enough for intubation
while 0.2-0.3 mg/kg for relaxation. Average duration
of action was 30-40 minutes, but could be prolonged
after heavy doses. Side effects were limited only
to mild hypotension and temporal face freshness,
while cardiovascular disturbances were very insig-
nificant. 相似文献
32.
Ni Yan-xia 《中国结合医学杂志》1995,(1)
TherapeuticEffectofBerberineon60PatientswithNon-InsulinDependentDiabetesMellitusandExperimentalResearchNiYan-xia(倪艳霞);LiuAn-q... 相似文献
33.
Dong Yong-sui 《中国结合医学杂志》1995,(1)
AStudyoftheMechanismofYinzhihuang(菌栀黄)InjectionintheTreatmentofInfantileHepatitisSyndromeDongYong-sui(董永绥);HuangZhi-hua(黄志华);... 相似文献
34.
Fa-Lin XU Chang-Lian ZHU Xiao-Yang WANG Department of Pediatrics the Third Affiliated Hospital of Zhengzhou University Zhengzhou China 《中国神经科学杂志》2006,(1)
Objective To study the developmental changes of glutamic acid decarboxylase-67 (GAD-67, a GABA synthetic enzyme) in normal and hypoxic ischemic (HI) brain. Methods C57/BL6 mice on postnatal day (P) 5, 9, 21 and 60, corresponding developmentally to premature, term, juvenile and adult human brain were investigated by using both Western blot and immunohistochemistry methods either in normal condition or after hypoxic ischemic insult. Results The immunoreactivity of GAD67 was up regulated with brain development and significant difference was seen between mature (P21, P60) and immature (P5, P9) brain. GAD67 immunoreactivity decreased in the ipsilateral hemisphere in all the ages after hypoxia ischemia (HI) insult, but, significant decrease was only seen in the immature brain. Double labeling of GAD67 and cell death marker, TUNEL, in the cortex at 8h post-HI in the P9 mice showed that (15.6±7.0)% TUNEL positive cells were GAD67 positive which was higher than that of P60 mice. Conclusion These data suggest that GABAergic neurons in immature brain were more vulnerable to HI insult than that of mature brain. 相似文献
35.
Wang Hongdu Liou Jinjong T. C. M. Hospital Luzhou Medical College Luzhou Sichuan China 《世界针灸杂志》1993,(1)
The study has explored 11 correlative variables which might affect the gallblad-der pressure GBP of patients with gall stone after auricular electrical stimulation by means of multiplestepwise regression. It was found that the size of gallbladder stone (X9), cholecystolithiasis (X4),sex (X1), and the baseline of GBP (X10) could affect the GBP change range (Y1) depressingly orreinforcingly. Also the baseline of GBP (Y1) could be affected by the variables X1 (sex), X2 (age),and X6 (long diameter of the gallbladder, LDGB), etc.. The result shows that the change in GBPafter auricular electrical stimulation is comprehensively influenced by multiple factors. And it providessome useful information for predicting the curative effect of auricular therapy on gallbladder stone inclinic. 相似文献
36.
Liu Ying-qi刘英奇 Yang Ji-fang杨济芳崇 Zhang Zhen-yu张振宇Zhang Xi-lan张希兰Qi Cui-e祁翠娥 Song Xiu-jun宋秀君Yang Jing-xia杨景霞and Wei Su-zhen魏素珍The Third Teaching Hospital Hebei Medical College Shijiazhuang 《中华医学杂志(英文版)》1988,101(4):280-283
Lactic dehydrogenase (LDH) activity in aqueoushumour and serum was measured of 24 patients withretinoblastoma, senile cataract, glaucoma, and cho-roid melanoma in addition to LDH isoenzyme fractions. The results were compared with those of the20 normal children. The ratio of aqueous humourLDH to serum LDH was 4.32+2.80, and that ofisoenzymes LDH4 to LDHl was greater than l. Theresults of our study suggested that the total LDHactivity and isoenzyme fractions in the aqueoushumour is of value in the diagnosis of retinobla&toma. 相似文献
37.
JIAN-QUN DONG* ZHEN-XIN ZHANG?AND KONG-LAI ZHANG* *School of Basic Medicine Peking Union Medical College/Chinese Academy of Medical Sciences Beijing Department of Neurology Peking Union Medical College Hospital Beijing China 《Biomedical and environmental sciences : BES》2003,(2)
INTRODUCTION Parkinson抯 disease (PD), a debilitating neurodegenerative disorder, is featured with bradykinesia, resting, muscular rigidity, gait disturbances, and postural reflex impairment[1]. PD is rare before age of 50 years, but it increases dramatically with older ages, with peak onset occurring during the age of 70-85 years. In the United States, prevalence of PD in all age groups is approximately 150 per 100 000 and is roughly 30 per 100 000 at age of less than 50 years and 800 … 相似文献
38.
Zhi-Qin Mao Mei Sun Department of Pediatrics Second Affiliated Hospital China Medical University Shenyang Liaoning Province China Ying Huang Hong Gao Department of Pediatric Surgery Second Affiliated Hospital China Medical University Shenyang Liaoning Province China Qiang Ruan Rong He Ying Qi Yu-Jing Huang Yan-Ping Ma Yao-Hua Ji Zheng-Rong Sun Virus Laboratory Second Affiliated Hospital China Medical University Shenyang Liaoning Province China 《World journal of gastroenterology : WJG》2007,(32)
AIM:To explore the genetic diversities of UL144 open reading frame (ORF) of cytomegalovirus DNA detected in colon tissue from infants with Hirschsprung's disease (HD) by sequencing UL144 DNA in 23 aganglionic colon tissue and 4 urine samples from 25 HD infants. METHODS:Nest PCR was performed for amplification of the UL144 gene. The UL144 gene was analyzed with softwares,such as DNAclub,BioEdit,PROSITE database,and DNAstar. RESULTS:The strains from HD patients were distributed among three genotypes of UL144:group 1A (64%),group 2 (24%),and group 3 (12%). The UL144 genotypes between strains from HD and control group were compared by chi square test (χ2 = 1.870,P = 0.393). Strains from the colon were sporadically distributed in UL144 genotypes. CONCLUSION:There are genetic diversities of UL144 ORF in colon tissue of infants with HD. However,cytomegalovirus UL144 genotypes are not associated with clinical manifestations of HD. 相似文献
39.
40.
Qiao Xiao-zhu乔孝珠 Wang Jin-lan王金兰 Zhou Yi-xin周意新 Wang Tie-xiu千铁秀and Su Zi-yin苏子吟Department of Pediatrics Beijing Zhongguancun Hospital Beijing 《中华医学杂志(英文版)》1987,100(8):669-670
Zinc is closely related to children's health
and growth.' We selected 120 children with
low serum zinc. Adopting random double-blind
method, we treated two groups of children,. 60
each, with sulphate zinc syrup and licorice acid
zinc capsules respectively. 相似文献