老年股骨粗隆间骨折三种内固定方法的评价

目的评价治疗股骨粗隆间骨折（ITF）三种术式的疗效。方法选择高龄患者71例,分为三组,即动力髋螺钉（DHS）组（26例）、股骨近端髓内钉（PFN）组（23例）、防旋股骨近端髓内钉（PFNA）组（22例）,三组患者平均年龄分别为74．4、75．1、78．5岁。对手术时间、术中出血量、术后出血量、手术切口长度等进行比较,结果采取LSD检验,进行两组间的分别对比。同时分析比较三种不同内固定方法的优缺点。结果（1）手术时间：三组间比较（P〈0．05）;PFNA组用时最短,PFN组次之,DHS组用时最长。（2）术中出血量：PFNA组与DHS组（P〈0．05）;PFNA组术中出血量较少。（3）术后出血量：PFNA组与DHS组（P〈0．05）;PFNA组出血量较少。另外DHS组和PFN组有切割现象、髋内翻、骨折延迟愈合等并发症,PFNA未发现上述并发症。结论PFNA在三种手术方式中由于创伤小,出血少,手术时间短,固定坚强,无切割现象等特点,适合于高龄患者中多种类型的粗隆间骨折。     

不同生长年限白芍中主要成分含量的比较研究

目的：比较不同生长年限的白芍中主要成分含量,为白芍规范化种植、采收提供科学依据。方法：采用HPLC法测定白芍中没食子酸、氧化芍药苷、芍药内酯苷、芍药苷、苯甲酸与1,2,3,4,6-五没食子酰葡萄糖含量。结果：随着生长年限的增加,没食子酸和苯甲酸含量逐年下降,而芍药苷、氧化芍药苷、芍药内酯苷和1,2,3,4,6-五没食子酰葡萄糖含量却逐渐增加。结论：4～5年生的白芍有效成分含量最高,适宜采收。     

应用色谱-质谱联用法快速鉴别人参和西洋参须根

目的 研究快速鉴别人参须根和西洋参须根的方法.方法 采用超高效液相色谱串联三重四级杆质谱(Ultra performance liquid chromatography-tandem quadrupole mass spectrometry,UPLC-TQ-MS/MS)法又称色谱-质谱联用方法进行快速分离和鉴定,采用ACQUITY UPLC BEH C18(2.1 mm×50mm,1.7 μm)色谱柱,柱温40℃,以乙腈-0.1％甲酸溶液为流动相梯度洗脱,流速0.5 ml/min;质谱采用电喷雾(ESI)离子源,全扫描和子离子扫描,负离子模式下采集数据.结果 在西洋参须根中检测到西洋参特征成分24(R)-拟人参皂苷F11,未检测到人参的特征成分人参皂苷Rf,而在人参须根中检测到人参的特征成分人参皂苷Rf,未检测到西洋参特征成分24(R)-拟人参皂苷F11.结论 所建立的色谱-质谱联用法能快速区分人参和西洋参须根.     

民航51名飞行员吸烟与不吸烟者的肺功能测定分析

对51名民航飞行员的肺功能进行测定分析．其中吸烟31名，平均吸烟指数为318．20支/年，平均飞行时同1．3万h，测定结果：最大呼气流量FEF25%～75%、FEF50％，FEF75％吸烟组与不吸烟组比较明显降低，有统计学意义。非吸烟组上述指标的异常率为32．40%．明显高于正常人。结果说明：吸烟对民航飞行员的肺功能影响以小气道损害为主，被动吸烟对不吸烟的民航飞行员影响较大。     

Effects of Shehuang Paste(麝黄膏) on hemodynamics, endotoxin, nitric oxide and endothelin-1 in patients with refractory cirrhotic ascites

Objective： To explore the influence of Shehuang Paste （麝黄膏, SHP） to the hemodynamics, endotoxin, nitric oxide （NO）, and endothelin-1 （ET-1） in patients with refractory cirrhotic ascites. Methods： Fifty-nine cases of refractory cirrhotic ascites were randomly assigned to two groups, 32 cases in the treatment group and 27 cases in the control group. The basic treatment was the same for both groups, including liver protecting medicines, diuretics and supportive drugs, but SHP navel sticking was applied for the treatment group additionally once a day. A course of one month of treatment was applied and the general efficacy on ascites was observed by the end of the therapeutic course. Before and after the treatment, examinations by limulus lysate chromogenic test was conducted to measure plasma endotoxin content; colorimetry to measure plasma content of NO indirectly, radioimmunoassay to measure plasma ET-1 content; and color Doppler ultrasonography to measure the blood flow of portal vein and splenic vein. The relationship between the blood flow of portal vein and splenic vein and endotoxin, NO and ET-1 in the treatment group was analyzed as well. Results： The total effective rate on ascites was 84.4% in the treatment group, and 48. 1% in the control group, with significant difference shown between them （P〈0.01）. In the treatment group the blood flow of portal vein and splenic vein, contents of endotoxin, NO and ET-1 all got significantly reduced after treatment （ P〈0.05 or P〈0.01）; while these indexes in the control group were not significantly changed （P〉0.05）. Moreover, it was found that in the treatment group, the blood flow of portal vein and splenic vein had a positive correlation to the levels of NO, ET-1, and endotoxin, either before or after treatment. Conclusion： Application of SHP navel sticking could clearly reduce the blood flow of portal vein and splenic vein, and lower the content of endotoxin, NO and ET-1. The blood flow of portal vein and splenic vein in the treatment group showed a positive correlation with the contents of endotoxin, NO and ET-1.     

自凝外固定架及临床应用

目的介绍一种新的外固定架及用法。方法以自凝树脂(骨水泥PMMA)和内固定钢针为固定材料,至2009年4月对102例四肢骨折进行外固定治疗。结果本组病例术后随访4~40个月,其中30例术后6周,60例术后8周,12例少于24周达临床愈合并去除外固定。未发生骨不连及关节强直者。结论自凝外固定架能代替和弥补传统成品外固定架的部分不足之处,是一种比较简廉可靠的外固定架。     

中西医结合治疗急性白血病30例

以扶正祛邪的中药清毒饮、养正片配合 HA、DA方案治疗急性血白病 30例。结果 :完全缓解 2 1例 ,部分缓解 3例 ,死亡 6例。并对持续缓解 8例及死亡的 6例分析 ,推测中药在中西医结合治疗中的作用。     

蚂蚁食疗研究概况

蚂蚁食疗在我国己有３０００多年的历史，存有丰富的文献和临床经验。近年来，在其成分分析、药理作用研究等方面取得很大进展，并广泛应用于临床，治疗类风湿性关节炎、乙型肝炎等多种病症。本文仅简略综述此方面的研究进展。     

参阿养血胶囊薄层色谱鉴别法

<正>参阿养血胶囊系以人参、阿胶、黄芪、当归等组成的中成药制剂。具有健脾补肾、益气养血等功效。本文应用薄层色谱法对其主要化学成分及药材分别进行了定性鉴别试验,证明其方法简便准确。     

血红林蚁的毒性实验研究

血红林蚁急性毒性试验无小鼠死亡,无法测出LD_(50);大鼠连续灌胃6个月,体征,行为正常,血液生化指标无异常,内脏检查无病变。表明服用血红林蚁安全。