Application of the dry‐spinning method to produce poly(ε‐caprolactone) fibers containing bovine serum albumin laden gelatin nanoparticles

We designed and manufactured a polymeric system with combined hydrophilic–hydrophobic properties by loading gelatin nanoparticles (GNPs) containing bovine serum albumin (BSA) into poly(ε‐caprolactone) (PCL) fibers. Our ultimate goal was to create a device capable of carrying and releasing protein drugs. Such a system could find several biomedical applications, such as those in controlled release systems, surgical sutures, and bioactive scaffolds for tissue engineering. A two‐step desolvation method was used to produce GNPs, whereas PCL fibers were produced by a dry‐spinning method. The morphological, mechanical, and thermal properties of the produced system were investigated, and the distribution of nanoparticles both inside and on the surface of the fibers was examined. The effect of the particles on the biodegradability of the fibers was also evaluated. In vitro preliminary tests were performed to study the release of BSA from nanoparticle‐laden fibers and to compare this with its release from free nanoparticles. Our results indicate that the distribution of particles inside the fibers was quite homogeneous and only a few of them were present on the surface. The presence of the particles in the fibers did not affect the thermal properties of the PCL polymer matrix, although it created voids that affected the degradation characteristics so the PCL fibers favored faster erosion compared to the plain fibers. Preliminary results indicate that the release from GNP‐laden fibers occurred much more slowly compared to that in the free GNPs. © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016 , 133, 44233.     

Geometrical and structural setting of landslide dams of the Central Alborz: a link between earthquakes and landslide damming

Bulletin of Engineering Geology and the Environment - The combination of remote sensing observations, geological field investigations and geomorphological mapping and measurements along with faults...     

Improving the performance of novel polysulfone-based membrane via sulfonation method: Application to water desalination

High-performance polymers for water desalination were designed. A novel polysulfone was prepared via reaction between a new synthesized pyridine-based diol and bis(4-fluorophenyl) sulfone. Also a series of disulfonated copolymers with sulfonation content of 20–50 wt% were prepared to compare the hydrophilicity with the pristine polymer. The generated membranes were characterized by microscopic, mechanical, and thermal methods, and the influence of sulfonation degree on hydrophilicity, water flux, and salt rejection was followed. Water flux of sulfonated membranes was increased compare to pristine membrane as sulfonation increased, while the salt rejection decreased. Optimum application performance was obtained for membrane with 30 wt% sulfonation content. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2020 , 137, 48568.     

Mixed matrix membranes on the basis of Matrimid and palladium-zeolitic imidazolate framework for hydrogen separation

Iranian Polymer Journal - Gas separation membranes with enhanced performance were developed by the introduction of nanosized palladium particles. In this study, gas separation performance of...     

Evaluation of a four-point sine wave frequency estimator for portable DSP based instrumentation

A recent frequency estimation method was proposed in a Measurement paper for use in portable DSP based instrumentation. This method is especially important due to its low computational effort making it suitable for fast and low cost instrumentation. It has been found that many parameters can affect the frequency estimation using the proposed method. In this paper, the performance of the method in the presence of additive noise is evaluated, and the influence of signal frequency, initial phase, additive noise and number of analog-to-digital converter bits on the estimator is studied. Some caveats of the practical use of the method are addressed. Detailed numerical simulations based on a Monte Carlo procedure are presented in order to highlight the range of applicability of the method and determine the estimation bias.     

Protection of titanium metal by nanohydroxyapatite coating with zirconia and alumina second phases

In this study hydroxyapatite (HA)/zirconia/alumina composite coatings on titanium metal was carried out using Sol-Gel dip coating and calcination process. Hydroxyapatite-Alumina-Zirconia sol, coated samples in three processes by changing final sol stirring time, aging time, calcination temperature of synthesized powder and prepared coating and rate of coating. Some parts of prepared sol were also synthesized and became powder in all three processes. Scanning electron microscopy was used to estimate the particle size of the surface and for morphological analysis. The functional group and crystallization characteristics of the powders were analyzed using (FTIR) and X-Ray diffraction (XRD). Results show that the morphology of HA-Alumina-Zirconia coatings is more homogenous in the second process with 2 hours final sol stirring time, 20 hours aging time under stirring at 60, 675°C calcination temperature for coating and 850°C for powder and 60mm/min rate of dip coating.     

Prevalence of virulent Yersinia enterocolitica in bulk raw milk and retail cheese in northern-west of Iran

To determine the prevalence of virulent Yersinia enterocolitica, 554 samples consisting of 354 bulk raw milks and 200 traditional cheeses were collected from different parts of Eastern-Azerbaijan province, during a 23-month period from 2008 to 2010. The occurrence of virulent strains of Y. enterocolitica in samples enriched in peptone sorbitol bile broth (PSBB) was evaluated via the detection of attachment invasion locus (ail) gene by PCR. The viability of virulent Y. enterocolitica in the PCR-positive samples was tested using conventional culture method and the isolates were confirmed by the second-phase ail-PCR. According to the results, 8.66% of total samples including 7.62% of bulk raw milks and 10.5% of raw milk cheeses were found ail-positive by PCR method; subsequently Y. enterocolitica was isolated by the culture method and confirmed by the second phase ail-PCR in 2.88% of total samples including 2.26% of raw milks and 4% of cheese samples. It was concluded that, a sample enrichment followed by ail-PCR was more sensitive and robust to detect and distinguish the virulent strains of Y. enterocolitica compared to the conventional culture method.     

A Novel Grounded Inductor Realization Using a Minimum Number of Active and Passive Components

In this study, we present a new topology for realizing a grounded inductor employing only a single current conveyor, called a negative‐type modified inverting second‐generation current conveyor (MICCII‐), and a minimum number of passive components, two resistors, and one capacitor. The non‐ideality effects of the MICCII‐on a simulated inductor are investigated. To demonstrate the performance of the presented inductance simulator, we use it to construct a third order Butterworth high‐pass filter and a parallel resonant circuit. Simulation results are given to confirm the theoretical analysis.     

Speed limit reduction in urban areas: A before–after study using Bayesian generalized mixed linear models

In fall 2009, a new speed limit of 40 km/h was introduced on local streets in Montreal (previous speed limit: 50 km/h). This paper proposes a methodology to efficiently estimate the effect of such reduction on speeding behaviors. We employ a full Bayes before–after approach, which overcomes the limitations of the empirical Bayes method. The proposed methodology allows for the analysis of speed data using hourly observations. Therefore, the entire daily profile of speed is considered. Furthermore, it accounts for the entire distribution of speed in contrast to the traditional approach of considering only a point estimate such as 85th percentile speed. Different reference speeds were used to examine variations in the treatment effectiveness in terms of speeding rate and frequency. In addition to comparing rates of vehicles exceeding reference speeds of 40 km/h and 50 km/h (speeding), we verified how the implemented treatment affected “excessive speeding” behaviors (exceeding 80 km/h). To model operating speeds, two Bayesian generalized mixed linear models were utilized. These models have the advantage of addressing the heterogeneity problem in observations and efficiently capturing potential intra-site correlations. A variety of site characteristics, temporal variables, and environmental factors were considered. The analyses indicated that variables such as lane width and night hour had an increasing effect on speeding. Conversely, roadside parking had a decreasing effect on speeding. One-way and lane width had an increasing effect on excessive speeding, whereas evening hour had a decreasing effect. This study concluded that although the treatment was effective with respect to speed references of 40 km/h and 50 km/h, its effectiveness was not significant with respect to excessive speeding-which carries a great risk to pedestrians and cyclists in urban areas. Therefore, caution must be taken in drawing conclusions about the effectiveness of speed limit reduction. This study also points out the importance of using a comparison group to capture underlying trends caused by unknown factors.     

New current-mode current-controlled universal filter with single input and three outputs

In this study, a new current-mode current-controlled universal filter with single input and three outputs is presented. The proposed circuit uses single-output current controlled conveyors (CCCIIs) and can simultaneously realize lowpass, bandpass and highpass filter functions all at high impedance outputs. Realization of notch and allpass responses does not require additional active elements. The circuit enjoys independent current-control of the parameters ω₀ and ω₀/Q without disturbing the gains of the lowpass, bandpass and highpass filters. Both its active and passive sensitivities are low.