Enabling personalisation of remote elderly assistance

One of the goals of Ambient Assisted Living (AAL) solutions is to extend the time that elderly people can live independently in their preferred environments by using ICT technologies for personal healthcare. However, in order to be optimal, remote monitoring services and health-related interventions should be strongly personalised to specific individuals’ requirements, preferences, abilities and motivations, which can vary among the elderly, and even dynamically evolve over time for the same person depending on changing user needs and context-dependent conditions. In this paper we present an End User Development (EUD) tool for the personalisation of context-dependent assistance by non-technical users in the AAL domain. In particular, we have considered applications for remotely monitoring and assisting elderly people at home through sending multimedia messages and reminders, as well as changing the state of various domestic appliances (e.g. lamps, heating system, TV) and devices available in the context surrounding the user. The design and development of the tailoring environment has been carried out in an iterative manner, informed by the feedback that was gathered through empirical evaluations done with older adults and caregivers.

     

The current state and future outlook of rescue robotics

Robotic technologies, whether they are remotely operated vehicles, autonomous agents, assistive devices, or novel control interfaces, offer many promising capabilities for deployment in real‐world environments. Postdisaster scenarios are a particularly relevant target for applying such technologies, due to the challenging conditions faced by rescue workers and the possibility to increase their efficacy while decreasing the risks they face. However, field‐deployable technologies for rescue work have requirements for robustness, speed, versatility, and ease of use that may not be matched by the state of the art in robotics research. This paper aims to survey the current state of the art in ground and aerial robots, marine and amphibious systems, and human–robot control interfaces and assess the readiness of these technologies with respect to the needs of first responders and disaster recovery efforts. We have gathered expert opinions from emergency response stakeholders and researchers who conduct field deployments with them to understand these needs, and we present this assessment as a way to guide future research toward technologies that will make an impact in real‐world disaster response and recovery.     

Toward characterizing HTML defects on the Web

HTML is being massively used as an interface to provide services to users. Web developers are producing and changing sites at a high pace while trying to support the latest HTML standards. In this context, it is common to find websites that do not comply with the standards and fail to be correctly processed by browsers. Considering this dynamic environment and the increasingly large diversity of browsers with frequent updates, the appearance of problems in web pages is a common, sometimes severe, and hard‐to‐track problem. In this short communication, we describe the initial design of an approach that will be used to obtain information regarding the characteristics of HTML documents on the Web and extract indicators of representative errors made by their developers. Preliminary results show nearly 90% of the pages analyzed having at least one type of error and the prevalence of a small number of error types.     

A comparison between K $K$ and G $G$ approaches for a viscoelastic material: the case of environmental stress cracking of HDPE

Mechanics of Time-Dependent Materials - According to linear elastic fracture mechanics the stress intensity factor and the energy release rate are two fracture parameters linked by the elastic...     

Correction to: Assessment of wastewater reuse potential for irrigation in rural semi-arid areas: the case study of Punitaqui,Chile

Clean Technologies and Environmental Policy - In this mentioned article, the Author names are mistakenly have been replaced with the family name of the authors, and so the family names with the names.     

Product/process definition,technology adoption and workforce qualification: impact on performance

This paper analyses the impact of manufacturing technologies (MTs) and workers’ qualifications on labour productivity and flexibility, taking into account the product-process (P-P) strategy adopted by the company. This allows for a discussion about the well-known P-P matrix initially proposed by Hayes and Wheelwright (1994) in order to evaluate options of production systems. The empirical analysis is performed by means of a panel of data of 13 years for the Spanish manufacturing industry, which includes a total of 7741 observations. The results indicate a complementary effect between technology and skills to overcome the trade-offs of production systems.     

Size‐Optimized Ultrasmall Porous Silica Nanoparticles Depict Vasculature‐Based Differential Targeting in Triple Negative Breast Cancer

Rapid sequestration and prolonged retention of intravenously injected nanoparticles by the liver and spleen (reticuloendothelial system (RES)) presents a major barrier to effective delivery to the target site and hampers clinical translation of nanomedicine. Inspired by biological macromolecular drugs, synthesis of ultrasmall (diameter ≈12–15 nm) porous silica nanoparticles (UPSNs), capable of prolonged plasma half‐life, attenuated RES sequestration, and accelerated hepatobiliary clearance, is reported. The study further investigates the effect of tumor vascularization on uptake and retention of UPSNs in two mouse models of triple negative breast cancer with distinctly different microenvironments. A semimechanistic mathematical model is developed to gain mechanistic insights into the interactions between the UPSNs and the biological entities of interest, specifically the RES. Despite similar systemic pharmacokinetic profiles, UPSNs demonstrate strikingly different tumor responses in the two models. Histopathology confirms the differences in vasculature and stromal status of the two models, and corresponding differences in the microscopic distribution of UPSNs within the tumors. The studies demonstrate the successful application of multidisciplinary and complementary approaches, based on laboratory experimentation and mathematical modeling, to concurrently design optimized nanomaterials, and investigate their complex biological interactions, in order to drive innovation and translation.     

Synthesis of bactericidal polymer coatings by sequential plasma-induced polymerization of 4-vinyl pyridine and gas-phase quaternization of poly-4-vinyl pyridine

Plasma-based technology is an alternative to produce universal polymer coatings with the appropriate requirements of robustness and stability for antibacterial applications. Here, we proposed a sequential two-step alternative to synthesize antibacterial polymer coatings. A non-isothermal plasma reactor, operated at atmospheric pressure (P_atm) and room temperature (T_room), was used to induce free radical polymerization of 4-vinyl pyridine (4VP) on high-density polyethylene (PE). In a subsequent step, the poly-4VP (P4VP) films were treated with a bromoethane/He gas stream to produce quaternized P4VP (P4VPQ) films. Chemical structure of polymer films was validated by infrared and UV–visible spectroscopy, and morphology was evaluated by optical and atomic force microscopy; scanning electron microscopy was used to determine films thickness, which was then used to estimate the surface charge density. The bactericidal capacity was determined with a standard test by using Escherichia coli. Both types of films had an estimated charge density in the order of 10¹⁶ positive charges per cm²; P4VP films removed about 95–99% of bacteria, whereas 4PVPQ films eliminated 100%. The methodology proposed for the synthesis of antibacterial polymer coatings is simpler, faster, and more environmentally friendly than other plasma-based methods; operation at T_room and P_atm may also have a significant effect on the economics and the ease of implementation of the process at commercial scale. The suggested approach may facilitate the development of new universal coatings, and operating plasma conditions could be extrapolated for engineering antibacterial coatings in industrial areas where bacterial attachment is of concern.     

Dry versus hydrated collagen scaffolds: are dry states representative of hydrated states?

Collagen composite scaffolds have been used for a number of studies in tissue engineering. The hydration of such highly porous and hydrophilic structures may influence mechanical behaviour and porosity due to swelling. The differences in physical properties following hydration would represent a significant limiting factor for the seeding, growth and differentiation of cells in vitro and the overall applicability of such hydrophilic materials in vivo. Scaffolds based on collagen matrix, poly(DL-lactide) nanofibers, calcium phosphate particles and sodium hyaluronate with 8 different material compositions were characterised in the dry and hydrated states using X-ray microcomputed tomography, compression tests, hydraulic permeability measurement, degradation tests and infrared spectrometry. Hydration, simulating the conditions of cell seeding and cultivation up to 48?h and 576?h, was found to exert a minor effect on the morphological parameters and permeability. Conversely, hydration had a major statistically significant effect on the mechanical behaviour of all the tested scaffolds. The elastic modulus and compressive strength of all the scaffolds decreased by ~95%. The quantitative results provided confirm the importance of analysing scaffolds in the hydrated rather than the dry state since the former more precisely simulates the real environment for which such materials are designed.

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Cavitation Bubbles Generated by Vibrating Quartz Tuning Fork in Liquid $$^$$He Close to the $$\lambda $$λ-Transition

We report direct optical observation of cavitation bubbles in liquid helium, both in classical viscous He I and in superfluid He II, close to the \(\lambda \)-transition. Heterogenous cavitation due to the fast-flowing liquid over the rough surface of prongs of a quartz tuning fork oscillating at its fundamental resonant frequency of \(4\,\mathrm {kHz}\) occurs in the form of a cluster of small bubbles rapidly changing its size and position. In accord with previous investigators, we find the cavitation threshold lower in He I than in He II. In He I, the detached bubbles last longer than one camera frame (10 ms), while in He II the cavitation bubbles do not tear off from the surface of the fork up to the highest attainable drive.