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71.
Zhang Huawei Yang Zhi Wu Zhaoyu Hong Xiaoyu Li Zhong Xu Yulai Li Jun Ni Gaojin Xiao Xueshan 《Oxidation of Metals》2019,92(1-2):49-65
Oxidation of Metals - The isothermal oxidation behavior and oxide-scale evolution on a newly developed Ni–Fe-based superalloy were investigated. Three oxidation stages were generally... 相似文献
72.
PROfound研究——前列腺癌精准治疗新希望 总被引:1,自引:0,他引:1
转移性去势抵抗性前列腺癌(metastatic castrate-resistant prostate cancer,mCRPC)是前列腺癌发展的终末阶段。患者生存预后很差。尽管不断地有新的治疗手段出现,比如新型内分泌治疗以及紫杉醇类化疗,mCRPC患者的生存期依然很有限。奥拉帕利是一款聚腺苷酸二磷酸核糖基聚合酶(poly ADP-ribose polymerase,PARP)抑制剂,PARP酶在DNA修复中扮演着重要的角色。奥拉帕利已经获批用于卵巢癌和乳腺癌的治疗。目前,奥拉帕利用于mCRPC治疗的III期临床研究PROfound的结果在2019年的欧洲肿瘤内科学会(ESMO)年会与2020年的美国临床肿瘤学会-泌尿生殖系统肿瘤研讨会(ASCO-GU)已经发布。本文将带来PROfound研究的结果以及最新的结果更新。 相似文献
73.
Jialin Sun Jun Zhao Xiuying Ni Feng Gong Zuoli Li 《Journal of the European Ceramic Society》2018,38(9):3096-3103
This work investigates the critical roles of two-step sintering (TSS) and laminated structure on the sintering behavior and mechanical properties of functionally graded WC-TiC-Al2O3 nanostructured composite materials doped with Cr3C2/VC. Results show that excellent mechanical properties are achieved for tailored TSS conditions with a hardness of 27.91?±?2.3?GPa and a flexural strength of 1423.3?±?23.5?MPa. The desirable mechanical properties are attributed to the suppressed grain growth without densification deterioration. TSS is more effective in facilitating the favorable dispersion of secondary phase toughening nano-particulates in a WC matrix than conventional sintering (CS). Cr3C2/VC dopant plays an important role in maximizing and shifting the temperature range of the kinetic window for WC-Al2O3 composites. Al2O3 crack deflection, transgranular Al2O3, microcracking, WC crack bridging and plate-like WC crack deflection are the major toughening mechanisms. Residual surface compressive stress induced by the graded structure is also an appreciated contribution to the improvement of mechanical properties. 相似文献
74.
75.
Zhuo Shi Ningning Dong Dingfeng Zhang Xiaofang Jiang Guanxin Du Shichao Lv Jiejie Chen Jun Wang Shifeng Zhou 《Journal of the American Ceramic Society》2019,102(7):3965-3971
The construction of nonlinear optical materials featuring asymmetric transmission of light is of great technological importance for various applications, including optical switching and optical power limiting. A significant challenge is the scalable fabrication of material candidates with good photochemical stability, high optical transmittance, and excellent optical limiting performance. Here, we present a nanocrystallization avenue for constructing hybrid optical limiting materials that exhibit ultrafast and robust optical limiting performance. The experimental results show that the controllable relaxation of a niobate glass may lead to the clustering of Nb-O units and contracting of the bandgap. It results in the notable improvement in nonlinear optical properties, including the enhanced saturation irradiance (380 GW/cm2), doubly increased nonlinear coefficient, and decreased limiting threshold (200 GW/cm2). Our results suggest a promising material that exhibits promising applications for protecting eyes and sensitive components from laser-induced damage. 相似文献
76.
77.
Qun Ren Haijun Su Jun Zhang Haifang Liu Weidan Ma Guangrao Fan Di Zhao Min Guo Lin Liu Hengzhi Fu 《Ceramics International》2019,45(6):6632-6638
Directionally solidified microstructures of Al2O3-Er3Al5O12 eutectic and off-eutectic in situ composite ceramics were explored under abrupt-change pulling rate conditions. Corresponding temperature distributions and interface locations were studied. In eutectic composition, fluctuation of eutectic spacing occurred when the pulling rate increased abruptly. A gradually increase or abrupt increase in eutectic spacing was observed when the pulling rate decreased abruptly. In hypoeutectic and hypereutectic compositions, formation of the primary phases were suppressed when the pulling rate increased abruptly from 10?µm/s to 100?µm/s, while primary phases precipitated when the pulling rate decreased abruptly from 100?µm/s to 10?µm/s. The interface altitude decreased after the pulling rate increased abruptly, but increased after the pulling rate decreased abruptly. The liquid composition restriction (around the eutectic composition) at the eutectic interface plays an important role in the suppression of the primary dendrite and coupled eutectic oxides can be obtained in off-eutectic compositions even under higher solidification rate conditions. 相似文献
78.
为了对八沟道等速万向节内套进行结构和静强度设计,从钢球选型出发,对八沟道等速万向节内套进行了结构参数正向设计.对内套危险截面进行了全场静强度设计,以理想静强度场为目标,定量匹配了危险截面静强度的材料、热处理,并对全场静强度设计进行了定量评价.使用MTS静扭转试验机对等速万向节总成进行了静强度扭转试验,并用显微硬度计对内套进行了显微硬度试验以验证理论,结果表明按照基于强度场的机械结构和零部件的静强度设计与匹配方法设计的八沟道等速万向节星形套能够满足强度和功能需求. 相似文献
79.
对PCB废水总氮的处理,从源头削减、分质收集、分质预处理到末端处理提出了多种方法,着重分析了MAP+管式微滤膜处理氨氮废水、多级组合式RO处理硝态氮废水和A2O+MBR处理综合废水,提出PCB废水总氮达标的组合工艺,项目建成后达到预期效果。 相似文献
80.