cis-1,3,4,6-Tetranitrooctahydroimidazo-[4,5-d]imidazole (BCHMX), its properties and initiation reactivity

Pre-treatment of simulated industrial wastewaters (SIM1, SIM2 and SIM3) containing organic and inorganic compounds (1,2-dichloroethane, sodium formate, sodium hydrogen carbonate, sodium carbonate and sodium chloride) by oxidative degradation using homogeneous Fenton type processes (Fe²⁺/H₂O₂ and Fe³⁺/H₂O₂) has been evaluated. The effects of initial Fe²⁺ and Fe³⁺ concentrations, [Fe^2+/3+], type of iron salt (ferrous sulfate vs. ferric chloride), initial hydrogen peroxide concentration, [H₂O₂], on mineralization extent, i.e., total organic content (TOC) removal, were studied. Response surface methodology (RSM), particularly Box–Behnken design (BBD) was used as modelling tool, and obtained predictive function was used to optimize the overall process by the means of desirability function approach (DFA). Up to 94% of initial TOC was removed after 120 min. Ferrous sulfate was found to be the most appropriate reagent, and the optimal doses of Fe²⁺ and H₂O₂ for reducing the pollutant content, in terms of final TOC and sludge production were assessed.     

Viscosity of cocoa butter

The viscosity of cocoa butter was measured in the range of temperatures 30‐70°C. Product in thawed state behaved as the Newtonian fluid with viscosity independent of shear rate. This behaviour was changed when the temperature reached 30°C. From this temperature the product behaved as non‐Newtonian fluid which was caused by the presence of the first fat crystals. The solidification was detected between 27‐30°C. A comparison of the measured data of viscosity with literature data has been done. The good agreement of literature data enabled us to select the general equation for prediction of cocoa butter viscosity in the thawed state as a function of temperature for the range 30‐97°C.     

ExPlanTech: Applying multi-agent systems in production planning

This paper presents work carried out within the 'ExPlanTech' project (IST-1999-20171) funded in part by the European Commission's Information Technologies Programme. The mission of the ExPlanTech technology transfer project is to introduce, customize and exploit the multi-agent production planning technology (ProPlanT multi-agent system research prototype) in two specific industrial enterprises. An agent-driven service negotiations and decision process, based on usagecentred knowledge about task requirements, substitutes the traditional production planning activity. We introduce a methodology for integration of the projectdriven production planning based on agent-based engineering within the existing enterprise resource planning system. This novel production planning technology will facilitate optimization of resource utilization and supplier chain while meeting the customer demands. This paper describes a FIPA-compliant implementation of the ExPlanTech technology at the LIAZ Pattern Shop manufacturing company. We describe the structure of the agent community, types of agents, implementation of the planning strategy and its incorporation within the real production environment.     

Phase Equilibria in the Sn-Rich Corner of the Ni-Sb-Sn System

Phase equilibria in the ternary Ni-Sb-Sn system are of interest for high-temperature soldering, both considering ternary alloys as solder materials themselves or as the basis for understanding the reactions between Sb-Sn-based solders and Ni-based substrates. Therefore, the Sn-rich corner of the ternary Ni-Sb-Sn phase diagram with Sn content of more than 75 at.% was investigated by a combination of powder x-ray diffraction (XRD), differential thermal analysis (DTA), and electron probe microanalysis (EPMA). Ternary phase equilibria and phase compositions of the respective equilibrium phases were determined within the isothermal section at 200°C, and two isopleths were constructed for constant Sn contents of 80 at.% and 85 at.%. The experiments were supported by CALPHAD-type calculations of this ternary system to yield a consistent reaction scheme which shows four invariant ternary transition reactions in this composition range. A liquidus projection is presented, accompanied by the corresponding Scheil diagram.     

Experimental evidence for the interaction of C-60 fullerene with lipid vesicle membranes

There are some molecular dynamic simulations but a paucity of experimental evidence of the effects of C-60 fullerene on lipid bilayers. The aim of this study is to assess the potential for disruption of the lipid bilayer by C-60 suspended in water. We selected a C-60 suspension that has previously been shown to provoke cell membrane destabilisation in vivo. Electromobility measurements show significant negative surface charge on the C-60 nanoparticles suspended in a glucose solution and a zeta potential of ?26 mV. The prevalent C-60 clusters have hydrodynamic radii of approximately 2 nm. Phase contrast microscopy and computer aided image analysis results show that C-60 causes shape transformations and rupture of unilamellar phospholipid vesicles, indicative of changes in their average mean curvature. Small-angle X-ray scattering reveals that C-60 provokes disruptions of external membranes of multilamellar vesicles only after freeze and thaw cycles. Here, the liposomes undergo breakage and annealing steps which increase the probability for fullerenes to insert into the MLVs. Our experimental findings confirm the potential of C-60 to reconstruct lipids in biological membranes. This research enhances our understanding of the impact of engineered nanoparticles on cell membranes.     

Chemical Synthesis,Sintering and Piezoelectric Properties of Ba0.85Ca0.15 Zr0.1Ti0.9O3 Lead‐Free Ceramics

The preparation of Ba_0.85Ca_0.15 Zr_0.1Ti_0.9O₃ (BCZT) powders by wet chemical methods has been investigated, and the powders used to explore relationships between the microstructure and piezoelectric properties (d₃₃ coefficient) of sintered BCZT ceramics. Sol–gel synthesis has been shown to be a successful method for the preparation of BCZT nanopowders with a pure tetragonal perovskite phase structure, specific surface area up to 21.8 m²/g and a mean particle size of 48 nm. These powders were suitable for the fabrication of dense BCZT ceramics with fine‐grain microstructures. The ceramics with the highest density of 95% theoretical density (TD) and grain size of 1.3 μm were prepared by uniaxial pressing followed by a two‐step sintering approach which contributed to the refinement of the BCTZ microstructure. A decrease in the grain size to 0.8–0.9 μm was achieved when samples were prepared using cold isostatic pressing. Using various sintering schedules, BCZT ceramics with broad range of grain sizes (0.8–60.5 μm) were prepared. The highest d₃₃ = 410.8 ± 13.2 pC/N was exhibited by ceramics prepared from sol–gel powder sintered at 1425°C, with the relative density of 89.6%TD and grain size of 36 μm.     

Analyses of moisture parameters and biomass of vegetation cover in southeast Moravia

The paper describes the analyses of moisture parameters and biomass of vegetation cover. These include a relative moisture classification, a relative biomass classification, and the actual aboveground biomass estimate. All analyses were carried out by applying spectral indices and fuzzy classification for assessment. The satellite imagery from the Thematic Mapper (TM) (Landsat 5) and the Enhanced Thematic Mapper Plus (ETM+) (Landsat 7) was used as input data. Biomass indices derived from the satellite imagery were correlated with table data of average crop yields in 2007. Since the imagery used was from three periods of time (May 2001, July 2007, August 2000), it could have been assessed in terms of both time dependence and phenological phases. The monitored variables during the year were the relative moisture and vegetation biomass. The territory of interest was the Trkmanka River basin in southeast Moravia. Time dependence was obtained with the results of classifications in terms of varying phenological phases as well as dependence between the two characteristics. The data from the comparison of May and June revealed primarily their increase (a decrease occurred only on arable land), whereas those from the comparison of July and August revealed mainly their decrease. The two characteristics show almost linear mutual dependence except for some forest land. We processed map outputs showing the spectral indices used, changes in relative moisture and relative biomass, the actual biomass estimate, and a deviation from a linear dependence of the two characteristics under examination. The selected indices were processed into Geoscientific Model Development (GMD) – models that can be repeatedly run in Model Maker in Earth Resources Data Analysis System (ERDAS) IMAGINE. Together with the models of spectral indices, these were optimized for the sensor TM and ETM+.     

Modeling functional requirements for configurable content- and context-aware dynamic service selection in business process models

In this article, we propose a meta-model for formal specification of functional requirements for configurable content- and context-aware dynamic service selection in business process models with the objective to enable greater flexibility of the modeled processes. The dynamic service selection can cope with highly dynamic business environments that today's business processes must handle. Modeling functional requirements for dynamic service selection in business process models is not well covered in literature. Some partial solutions exist but none of them allows modeling a complete set of functional requirements for the selection similar to the one we are addressing in this article. Our meta-model enables formal specification of service selection relevant data extracted from service request message, custom configuration data (e.g., thresholds), process and task definition/instance metadata, and service selection rules. The meta-model is configurable and content- and context-aware. Processes leveraging our meta-model can adapt to changing requirements without redesign of the process flow. Proposed meta-model allows users to additionally configure the models at run time (e.g., raising a threshold). Modeling can be divided into roles with different required competences. We implement our meta-model in BPMN 2.0 (Business Process Model and Notation) through specific extensions to the BPMN semantic and diagram elements. By measuring complexity of real-world sample process models we show that using our solution modelers can efficiently model business processes that need to address frequent changing demands. Compared to available alternatives, models using our solution have on average ～13% fewer activities, ～16% fewer control-flow elements and ～22% fewer control paths. By reading ～10% smaller models (by volume) model readers get more flexible process models that capture all functional requirements for the dynamic selection.     

Analysis of reliability and optimization of ESD protection devices supported by modeling and simulation

An analysis of electrostatic discharge (ESD) protection structures supported by advanced 2-D mixed mode electro-thermal device and circuit simulation with calibrated electro-physical models to increase the reliability of protected IC’s is presented. The critical temperature as a criterion of device destruction is defined and experimentally verified. Numerical simulation and visualization of the internal electro-physical properties of the analyzed structures during a very short ESD pulse considerably improved the understanding of their physical behavior and contributes to a proper design and optimization of doping and geometry of the analyzed ESD protection devices. The analyzed devices are designed as protection against Human Body Model (HBM) and International Electromechanical Commission model (IEC) 61000-4-2 with very high robustness. The obtained results are shown on two examples. Modification of the device layout by splitting the cathode contact of the ESD diode into two parts allowing area reduction with improved electrical characteristics is the subject of the first example. The influence of doping fluctuations on the device robustness is presented in the second example. Different triggering and failure mechanisms of the diode and transistor structure during HBM and IEC pulse are presented.     

Does an alteration of dialyzer design and geometry affect biocompatibility parameters?

The aim of the study was to assess the biocompatibility profile of a newly developed high-flux polysulfone dialyzer type (FX-class dialyzer). The new class of dialyzers incorporates a number of novel design features (including a new membrane) that have been developed specifically in order to enhance the removal of small- and middle-size molecules. The new FX dialyzer series was compared with the classical routinely used high-flux polysulfone F series of dialyzers. In an open prospective, randomized, crossover clinical study, concentrations of the C5a complement component, and leukocyte count in blood and various thrombogenicity parameters were evaluated before, and at 15 and 60 min of hemodialysis at both dialyzer inlet and outlet in 9 long-term hemodialysis patients using the FX60S dialyzers and, after crossover, the classical F60S, while in another 9 patients, the evaluation was made with the dialyzers used in reverse order. The comparison of dialyzers based on evaluation of the group including all procedures with the FX60S and the group including procedures with the F60S did not reveal significant differences in platelet count, activated partial thromboplastin times, plasma heparin levels, platelet factor-4, D-dimer, C5a, and leukocyte count at any point of the collecting period. Both dialyzer types showed a significant increase in the plasma levels of the thrombin-antithrombin III complexes; however, the measured levels were only slightly elevated compared with the upper end of the normal range. Biocompatibility parameters reflecting the behavior of platelets, fibrinolysis, complement activation, and leukopenia do not differ during dialysis with either the FX60S or the F60S despite their large differences in design and geometry features. Although coagulation activation, as evaluated by one of the parameters used, was slightly higher with the FX60S, it was still within the range seen with other highly biocompatible dialyzers and therefore is not indicative of any appreciable activation of the coagulation system. Thus, the incorporation of various performance-enhancing design features into the new FX class of dialyzers does not result in a deterioration of their biocompatibility profile, which is comparable to that of the classical F series of dialyzers.