Screening and Identifying of Nephrotoxic Compounds in Lithospermum erythrorhizon Using Live-cell Fluorescence Imaging and Liquid Chromatography Coupled with Tandem Mass Spectrometry

In order to identify the potential nephrotoxic compounds in traditional Chinese medicine Lithospermum erythrorhizon,it was separated into serial fractions according to their polarities.An in vitro method was utilized to determine the nephrotoxicity of these fractions with the help of fluorescence image analysis.As a result,the primary fraction A05 and its secondary fractions C06 C09 and C12 C14 were found to have significant toxicity to LLC-PK1 cell line,as determined by the survive rate less than 20% after...     

Nanocatalytic resonance scattering spectral analysis

The resonance scattering spectral technique has been established using the synchronous scanning technique on spectrofluorometry.Because of its advantages of simplicity,rapidity and sensitivity,it has been widely applied to analyses of proteins,nucleic acids and inorganic ions.This paper summarizes the application of immunonanogold and aptamer modified nanogold(AptAu) catalytic resonance scattering spectral technique in combination with the work of our group,citing 53 references.     

What is the Euler’s Method?(2)

Solution: Since we know y=f(x)=x2+x-1, so get the initial value at x=1, which is f(1)=1,and also we can get y’=2x+1.     

C~l -G_V TRIVIALITY OF FUNCTION GERMS AND NEWTON POLYHEDRA

We provide estimates on the degree of C l GV determinacy ( G is one of Mather’s groups R or K ) of function germs which are defined on analytic variety V and satisfies a non-degeneracy condition with respect to some Newton polyhedron. The result gives an explicit order such that the C l geometrical structure of a function germ is preserved after higher order perturbations, which generalizes the result on C l G triviality of function germs given by M.A.S.Ruas.     

Synergistic effect between Sn and K promoters on supported platinum catalyst for isobutane dehydrogenation

Catalytic dehydrogenation of isobutane has recently received considerable attention because of the increasing demand for isobutene.In this study,the synergistic effect between Sn and K on PtSnK/γ-Al2O3 catalysts has been investigated by changing the content of Sn.It was found that with the presence of potassium,suitable addition of Sn could not only increase the metal dispersion,but also reduce the catalyst acidity.In these cases,the synergistic effect could also strengthen the interactions between the metal and support,which resulted in an increase in both catalytic activity and stability.In our experiments,Pt-0.6SnK/Al catalyst exhibited the lowest deactivation rate (12.4%) and showed a selectivity to isobutene higher than 94% at the isobutane conversion of about 45.3% after running the reaction for 6 h.However,with the excessive loading of Sn,surface property of active sites and the interactions between metal and support were changed.As a result,the initial optimal ratio between the metallic function and acid function would be destroyed,which was disadvantageous to the reaction.     

Electrochemical Cycled Structure of MnV_2O_6 Nanoribbons Synthesized via Hydrothermal Route

1 Introduction Low-dimensional nanostructures, such as nanorods, nanowires, and nanotubes, have received much attention for their superior optical, electrical, catalytic and magnetic properties.     

Active TLCGD control of plane asymmetric buildings under earthquake excitation

The sealed,tuned liquid column gas damper (TLCGD) with gas-spring effect extends the frequency range of application and efficiently increases the modal structural damping.Active tuned liquid column gas damper (ATLCGD) is developed for the vibration control of plane asymmetric buildings subjected to earthquake excitation,improving the performance of the passive control scheme.The active behaviour is obtained by adjusting the pressure at the end of the liquid column using a pressurised reservoir.The classical linear quadratic regulator (LQR) design is presented as a straightforward approach to optimal control.Numerical simulations indicate a significant vibration reduction of plane asymmetric buildings by active control within the strong motion of the dynamic response.     

Understanding the endocrine disruption of chiral pesticides:The enantioselectivity in estrogenic activity of synthetic pyrethroids

Synthetic pyrethroids(SPs) ,a family of chiral insecticides consisting of multiple stereoismers,have been regarded as estrogenic endocrine-disrupting chemicals(EDCs) .In this study,we applied the yeast two-hybrid and molecular docking(MD) assay to assess the enantioselective estrogenic activities of three commonly used SPs,bifenthrin(cis-BF) ,permethrin(PM) and fenvalerate(Fen) .The β-galactosidase analyses indicated that all of the testing pyrethroids displayed significant(p<0.05) enantioselectivity.The re...     

Valence of elements in HgBa_2Ca_(n-1)Cu_nO_(2n+2+δ)(n=1, 2, 3, 4)

HgBa2Can-1CunO2n+2+( (n=1, 2, 3, 4) 1 are tetragonal with space group space P4/mmm. For n=1,2,3, nearly single-phase crystals were obtained, while for n=4, the sample was primarily a mixture of the n=3 and 4 phases. These materials also possessed the highest Tc values yet observed for any superconductors. In this paper, the valences of elements in the title compounds were calculated from bond valence sum method 2. The calculated bond covalency, valences of elements were summarized in Table …     

新型聚乙烯醇系亲和吸附剂的制备及其在糖蛋白纯化中的应 …

利用已合成的聚醋酸乙烯酯－甲基丙烯酸缩水甘油酯－甲基丙烯酸烯丙酯大孔共聚物。醇解后与６－氨基正已酸反应，进一步在ＥＤＡＣ的作用下实现与间氨基苯硼酸的偶联，得到亲水性的亲和吸附剂；配基密度为０．８６５ｍｍｏｌ／ｇ干树脂，偶联效率为８９％，以云芝糖肽八方地，吸附容量为５３．７ｍｇ／ｇ干树脂，为醇解前的７．７倍。