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81.
YF NGEOW AF WEIL NS KHAIRULLAH MY MOHD YUSOF L LUAM C GAYDOS TC QUINN 《Journal of paediatrics and child health》1997,33(5):422-425
Objective: The incidence of Chlamydia pneumoniae and Chlamydia trachomatis infection was studied among infants and young children admitted to hospital for the management of lower respiratory tract infections, over a 12 month period.
Methodology: Respiratory secretions were examined for chlamydiae by cell culture, enzyme-linked immunosorbent assay and polymerase chain reaction-enzyme immunoassay. Sera were tested by micro-immunofluorescence for chlamydial IgG, IgM and IgA. Other bacterial and viral pathogens were also looked for by standard cultural and serological methods.
Results: Of 87 patients aged 2 months-3 years, an aetiologic diagnosis was made in 41 (47.1%). C. pneumoniae and C. trachomatis were each detected in 1 (1.2%) of the patients. Among common bacterial pathogens, Haemophilus influenzae (13.8%) and Streptococcus pneumoniae (8.1%) were the most frequently identified. Respiratory viruses and elevated Mycoplasma pneumoniae antibodies were found in 10.3% and 9.1% of patients, respectively.
Conclusion: Chlamydiae are infrequent causes of community-acquired acute lower respiratory tract infections in infants and very young children in Malaysia. 相似文献
Methodology: Respiratory secretions were examined for chlamydiae by cell culture, enzyme-linked immunosorbent assay and polymerase chain reaction-enzyme immunoassay. Sera were tested by micro-immunofluorescence for chlamydial IgG, IgM and IgA. Other bacterial and viral pathogens were also looked for by standard cultural and serological methods.
Results: Of 87 patients aged 2 months-3 years, an aetiologic diagnosis was made in 41 (47.1%). C. pneumoniae and C. trachomatis were each detected in 1 (1.2%) of the patients. Among common bacterial pathogens, Haemophilus influenzae (13.8%) and Streptococcus pneumoniae (8.1%) were the most frequently identified. Respiratory viruses and elevated Mycoplasma pneumoniae antibodies were found in 10.3% and 9.1% of patients, respectively.
Conclusion: Chlamydiae are infrequent causes of community-acquired acute lower respiratory tract infections in infants and very young children in Malaysia. 相似文献
82.
The production of leukaemia inhibitory factor by human endometrium: presence in uterine flushings and production by cells in culture 总被引:12,自引:5,他引:12
Laird SM; Tuckerman EM; Dalton CF; Dunphy BC; Li TC; Zhang X 《Human reproduction (Oxford, England)》1997,12(3):569-574
The concentration of leukaemia inhibitory factor (LIF) was measured in
uterine flushings obtained from normal fertile women, from women with
unexplained infertility and from women who suffered recurrent miscarriage.
In normal fertile women, LIF was not detected in flushings obtained on days
luteinizing hormone (LH)+0 to LH+6 of the cycle, but concentrations
gradually increased from day LH+7 to a maximum at day LH+12. The amount of
LIF in flushings obtained from women with unexplained infertility was
significantly lower than in those from normal fertile women on day LH+10 (P
< 0.05). The production of LIF by cultured human epithelial and stromal
cells was also investigated. LIF was not detectable in the supernatants of
cultured stromal cells. Basal LIF production by epithelial cells varied
according to the stage in the cycle at which the biopsy was taken.
Significantly more LIF was produced by epithelial cells from late
proliferative and early secretory endometrium compared with amounts
produced by cells from early proliferative (P < 0.001) and late
secretory (P < 0.01) endometrium. High doses of progesterone and
oestradiol caused a small decrease in epithelial cell LIF production: the
combined effect of progesterone and oestradiol (P < 0.01) was greater
than the effect of either steroid alone (P < 0.05). The results show,
for the first time, the capability of human endometrium to produce LIF in
vivo. The fact that maximum LIF concentrations are present at implantation
and that decreased concentrations occur in women with unexplained
infertility suggest the importance of this cytokine in embryo implantation.
相似文献
83.
Cytokines and immuno-endocrine factors in recurrent miscarriage 总被引:7,自引:0,他引:7
Recurrent miscarriage remains an enigma. The main aetiologiesare endocrinological, immunological and unexplained. With thegrowth in molecular biology, it is now possible to look at theeffect of these aetiologies in more detail, allowing greaterunderstanding of the underlying pathogenesis. Keywords: cytokines/recurrent miscarriage 相似文献
84.
Sphincter of Oddi stenosis: diagnosis using hepatobiliary scintigraphy and endoscopic manometry 总被引:3,自引:0,他引:3
To determine the role of radionuclide imaging in diagnosing sphincter of Oddi stenosis, 21 patients with symptoms suggesting this disorder underwent endoscopic retrograde cholangiopancreatography, cholescintigraphy, and, when possible, endoscopic manometry. Those patients with abnormal hepatobiliary scintigraphy results--based on our criteria of delayed biliary intestinal transit, abnormal duct size, and abnormal time-activity dynamics and obstruction--had a mean basal sphincter pressure of 38.5 mm Hg. Sphincter pressures could not be measured in six patients with sphincters too tight to cannulate. Ten patients who underwent hepatobiliary scanning both before and after sphincter surgery had normal scan results on the repeat study. Hepatobiliary imaging appears useful for diagnosis of sphincter of Oddi stenosis in selected patients in whom manometry cannot be performed and for objective assessment of response to therapy. 相似文献
85.
Rapid assessment of a patient with possible major peripheral vascular injury is essential to preserve limb function. Intravenous digital subtraction angiography (IV DSA) allows rapid evaluation of these patients without the need for intraarterial examination. We report our experience in 295 vessels studied by IV DSA for the evaluation of possible traumatic arterial injury to the extremities or neck. Of our study population requiring angiography (469 patients), 63.4% were appropriate candidates for IV DSA. Of the vessels studied by IV DSA, 93.6% required no further radiologic evaluation. A normal appearance on IV DSA study indicates no major vascular injury; patients with positive studies may proceed to surgery without further interventional assessment. 相似文献
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89.
The interstitial fluid pressure of the submucosa of the gastric fundus was monitored by means of Guyton's capsules in dogs anesthetized with pentobarbital. The intracapsular pressure (ICP) was measured during secretion produced by: a) hypertonic solutions placed inside the stomach; b) arterial hypertension (200 mmHg) applied during intra-arterial infusion of histamine, and c) intra-arterial infusion of acetylcholine. The first procedure did not modify the ICP. On the other hand, whenever interstitial fluid appeared in the gastric lumen during hypertension plus histamine, the mean ICP increased, mostly due to augmented capillary filtration. The hydraulic coefficient measured in these experiments was at least 4 orders of magnitude larger than the respective osmotic coefficient. The action of acetylcholine was complex: large doses enlarged the net capillary filtration, but small doses increased the mean ICP by muscle stimulation only. Contraction of the muscularis mucosae might be the most important mechanism underlying bulk flow of interstitial fluid in physiological conditions. It is concluded that hydraulic gradients across the epithelium might account for the "secretion" of "alkaline" juice. 相似文献
90.