Comparison of essential oils compositions of Nepeta persica obtained by supercritical carbon dioxide extraction and steam distillation methods

Essential oil of Nepeta persica cultivated in Iran was obtained by steam distillation and supercritical (carbon dioxide) extraction methods. The oils were analysed by capillary gas chromatography using flame ionization and mass spectrometric detections. The compounds were identified according to their retention indices and mass spectra (EI, 70 eV). The effects of different parameters such as pressure, temperature, modifier volume and extraction times (dynamic and static) on the supercritical fluid extraction (SFE) of N. persica oil were investigated. The results showed that under the pressure of 20.3 MPa, temperature of 45 °C, methanol of 1.5% v/v), dynamic extraction time of 50 min and static extraction time of 25 min extraction was more selective for the 4αβ,7α,7aα-nepetalactone. Twelve compounds were identified in the steam-distilled oil. The major components of N. persica were 4αβ,7α,7aα-nepetalactone (26.5%), cis-β-farnesene (4.4%) and 3,4α-dihydro-4aα,7α,7aα-nepetalactone (3.5%). However, by using supercritical carbon dioxide under optimum conditions, only two components have more than 90.0% of the oil. The extraction yield based on steam distillation was 0.08% (v/w). On the other hand, using SFE extraction yield in the range of 0.22–8.90% (w/w) were obtained at different conditions. The results show that, in Iranian N. persica oil, 4αβ,7α,7aα-nepetalactone is a major component.     

A new representation for the Green's function of multilayer media based on plane wave expansion

In this paper, a new representation for the space domain Green's function of general multilayer media is presented. This approach is based on an efficient plane wave expansion of the source incident field. Using the transmission line model for the multilayer medium, the effect of the layered medium on the incident plane waves is determined by a transmission coefficient, and the amplitude and phase of each plane wave at the field point are obtained. The total field is evaluated by summing the resultant plane waves at the field point. The main advantage of the proposed method is that the spatial domain Green's function of multilayer media can be obtained easily as a summation of simple exponential functions, without the need for Sommerfeld integration or complex image approximation. The plane wave approximation is independent of the parameters of the medium and is valid over a wide frequency range. Furthermore, the exponential form of the plane wave solution makes it possible to compute the method of moments matrix elements analytically for most important types of basis functions in multilayer problems.     

Brittle fracture in rounded-tip V-shaped notches

Two failure criteria are proposed in this paper for brittle fracture in rounded-tip V-shaped notches under pure mode I loading. One of these criteria is developed based on the mean stress criterion and the other based on the point stress criterion which both are well known failure criteria for investigating brittle fracture in elements containing a sharp crack or a sharp V-notch. To verify the validity of the proposed criteria, first the experimental data reported by other authors from three-point bend (TPB) and four-point bend (FPB) tests on PMMA at −60 °C and Alumina–7% Zirconia ceramic are used. Additionally, some new fracture tests are also carried out on the rounded-tip V-notched semi-circular bend (RV-SCB) specimens made of PMMA for various notch opening angles and different notch tip radii. A very good agreement is shown to exist between the results of the mean stress criterion and the experimental data.     

A novel ±0.5 V,high current drive,and rail to rail current operational amplifier

A current operational amplifier (COA) with very high current drive capability is presented in this paper. The principle of operation of this unique structure is discussed, its most important formulas are derived and its outstanding performance is verified by HSPICE simulation in TSMC 0.18 μm CMOS, BSIM3, and Level49 technology. Owing to the elaborately arranged components, the proposed circuit demonstrates very high frequency bandwidth, extremely high CMRR, high output impedance, and true rail to rail output voltage swing range while operating at very low power supply of ±0.5 V. The interesting results such as current drive capability of ±1 mA, high output impedance of 5 GΩ, wide gain bandwidth of 220 MHz, extremely high output voltage swing of ±0.45 V, which interestingly provides the highest yet reported output voltage compliance for current mode building blocks implemented by regular CMOS technology, low static power consumption of 159 μW, and very high CMRR of 155 dB is achieved utilizing standard CMOS technology. Full process, voltage, and temperature variation analysis of the circuit is also investigated in order to approve the well robustness of the structure. The transient stepwise and sinusoidal response analysis is also done to verify the proposed COA stability.     

Fracture toughness study for a brittle rock subjected to mixed mode I/II loading

A semi-disk specimen containing an angled edge crack has been used in the past for conducting fracture tests on a brittle rock named Johnstone [Fracture testing of a soft rock with semi-circular specimens under three-point bending. Part 2—mixed mode. Int J Rock Mech Min Sci Geomech Abstr 1994b;31(3):199–212]. The test specimen is appropriate for investigating brittle fracture when the rock samples are subjected to the combined effects of tension and shear along the crack line. However, the experimental results reported in Lim, Johnston, Choi, Boland [Fracture testing of a soft rock with semi-circular specimens under three-point bending. Part 2—mixed mode. Int J Rock Mech Min Sci Geomech Abstr 1994b;31(3):199–212.] are inconsistent with all of the well-known theoretical criteria available for predicting mixed mode brittle fracture. In this paper, a modified criterion is used to provide accurate predictions for the reported experimental results. The modified criterion makes use of a three-parameter model (based on K_I, K_II and T) for describing the crack tip stresses. It is shown that the non-singular stress term T has a significant role when the rock fracture tests are conducted on the semi-disk specimens.     

Simultaneous enantioseparation and tandem UV-MS detection of eight beta-blockers in micellar electrokinetic chromatography using a chiral molecular micelle

The feasibility of using a new and more versatile polymeric chiral surfactant, i.e., poly(sodium N-undecenoxy carbonyl-L-leucinate (poly-L-SUCL) is investigated for simultaneous enantioseparation and detection of eight structurally similar beta-blockers with tandem UV and MS detection. Three optimization approaches, i.e., direct infusion-MS, capillary zone electrophoresis-MS, and chiral micellar electrokinetic chromatography-mass spectrometry (CMEKC-MS), were investigated to optimize sheath liquid parameters, spray chamber parameters, and CMEKC separation parameters for maximum sensitivity and chiral resolution. Compared to unpolymerized micelle of L-SUCL, the use of micelle polymer (i.e., poly-L-SUCL) provided significantly higher separation efficiency, lower separation current, and higher detection sensitivity for CMEKC-ESI-MS of beta-blockers. It was also observed that, unlike monomeric L-SUCL, polymeric L-SUCL provided enantioseparation of all beta-blockers even at the lowest surfactant concentration (i.e., 5 mM poly-L-SUCL). Under optimum CMEKC and ESI-MS conditions (15 mM poly-L-SUCL, 25 mM each of NH4OAc and TEA (pH 8.0); 80% (v/v) methanol sheath liquid containing 40 mM NH4OAc (pH 8.0); sheath liquid flow rate, 5.0 microL/min; drying gas flow rate, 5 L/min; drying gas temperature, 200 degrees C; nebulizing pressure, 6 psi (0.414 bar); capillary voltage, +2.5 kV; fragmentor voltage, 85 V), baseline enantioseparation of eight beta-blockers was achieved by tandem UV (in approximately 30 min) and MS (in approximately 60 min) detection. Calibration curves for all beta-blockers were linear in the range of 0.01-0.6 mM for both CMEKC-UV and CMEKC-MS methods, but the later method provided better concentration limit of detection with similar RSD for migration time and peak areas. The CMEKC-ESI-MS method appears suitable for use as a routine procedure for high-throughput separation of beta-blockers with high sensitivity.     

Finite element analysis of a center crack specimen warm pre-stressed under different modes of loading

Load bearing capacity of cracked specimens can be improved following pre-loading procedures like warm pre-stressing (WPS). In this paper, the effects of modes I and II pre-loading on fracture load of a central angled crack specimen are studied by finite element analysis. The specimen is reloaded either in mode I or in mode II. To predict the fracture load of cracked specimen after pre-loading, the maximum tensile stress (MTS) and maximum shear stress (MSS) criteria are used. It is shown that mode II fracture load is independent of pre-loading but the mode I fracture load is highly improved after warm pre-stressing. The mode mixity of the specimen is also changed when the pre-loading and reloading modes are not identical. An increase in the fracture load of the specimen following pre-loading may be due to change of failure mode as predicted by finite element analysis in this work.     

Computation of stress intensity factors (KI, KII) and T-stress for cracks reinforced by composite patching

To increase the operational life of defected structures, a repairing method using composite patches has been used to reinforce cracked components. Due to various advantages of composite materials, this method has received much attention from researchers and engineers. Considerable investigations have been performed to highlight the effect of bonded composite patches on the fracture parameters such as stress intensity factors (SIF) and J-integral. However the effect of composite patches on the T-stress, the constant stress term acting parallel to the crack, has not been investigated in the past. In this paper, the finite element method is carried out to analyze the effect of bonded composite patches for repairing cracks in pure mode I and also mixed mode I/II conditions, by computing the stress intensity factors and the T-stress, as functions of the crack length, the crack inclination angle and the type of composite material. In pure mode I condition, the finite element analysis is carried out for three different specimens: centre crack, double edge crack and single edge crack specimens. For mixed mode I/II condition the analysis is conducted on an inclined central crack of various slant angles. For both pure mode I and mixed mode I/II, the numerical results show that composite patching has considerable effect on the T-stress.