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81.
82.
盖凌洋 《沈阳建筑工程学院学报(自然科学版)》1996,12(2):132-137
通过模拟计算与分析,提出了种无梁板支承条件的调整方式,并对调整后结构的内力影响问题进行讨论。 相似文献
83.
Gai MN Ferj S García E Seitz C Thielemann AM Andonaegui MT 《Drug development and industrial pharmacy》1999,25(2):131-140
Two sustained-release (SR) lithium carbonate (Li) matrix tablets, which use a hydrophilic (HP) matrix of hydroxypropylmethylcellulose (Methocel 4K MP) and a lipid (L) matrix of hydrogenated castor oil (Cutina HR) as sustaining agents, have been studied. In vitro performance through dissolution tests in different media was established. The L and HP formulations were affected by the composition of the dissolution media, and liberation was complete in 8 hr using a variable-pH medium that simulates the gastrointestinal (Gl) pH. Liberation was better described by the diffusional model of the square root of time for the L matrix and by zero-order kinetics for the HP matrix. Absolute bioavailability (BA) and food-induced changes on BA of both formulations were studied. The in vivo study design was a 4 x 4 Latin square involving 12 subjects who received two tablets of a 300-mg dose of SR formulations while fasting or with a standardized normal, high-fat, or high-fat/high-protein meal. The results for both formulations showed no differences in the disposition parameters and mean residence time when the tablets were administered with any type of diet. Changes in rate of absorption were found when both types of tablets were administered with any class of diet. The analysis of the ratio Cmax/AUC (area under the curve) evidenced that changes in Cmax were attributable to a higher rate of absorption for the HP matrix and to a higher amount absorbed for the L matrix. In the last, high-fat and high-fat/high-protein diets produced higher AUCs than under fasting condition. The SR Li tablets formulated with hydrogenated castor oil were affected more by high-fat food, probably because of the increase of pancreatic and biliary secretions promoted by the meal, which would affect the matrix itself. The HP matrix was also affected, but to a lesser extent. The magnitude of the change in Cmax observed with this matrix probably is not important from a clinical point of view. Absolute BA was very low for the lipid matrix; in addition, since it is more seriously affected by food, probably it is not a good choice for a drug such as lithium. The in vivo behavior of the HP matrix makes it advisable to invest in efforts to achieve increased BA. Comparing in vitro and in vivo results, the focus should be achieving sustained, but complete, in vitro liberation in not more than 3 hr, with simulation of the transit time through the stomach and small bowel since lithium ion is only absorbed to this point. 相似文献
84.
Through hydrogen reduction of metal precursors in supercritical CO2, Cu, and Pd, nanocrystals were deposited onto SiO2 nanowires to form different types of nanostructured materials, including nanocrystal-nanowire, spherical aggregation-nanowire, shell-nanowire composites, and "mesoporous" metals supported by the framework of nanowires. This supercritical fluid deposition technique is an attractive approach for modifying nanowires because of its generality and simplicity; the modified nanowires could be useful as catalysts and for further fabrication of multifunctional composites. 相似文献
85.
86.
Zhiguo Ren Wenjing Gai Fan Zhong Julien Pettré Qunsheng Peng 《The Visual computer》2013,29(9):927-936
In this paper, we propose a novel approach to integrate virtual pedestrians into a scene of real pedestrian groups with behavior consistency, and this is achieved by dynamic path planning of virtual pedestrians. Rather than accounting for the local collision avoidance only, our approach is capable of finding an optimized path for each virtual pedestrian on his way based on the current global distribution of the real groups in the scene. The big challenge is due to the information of both position and velocity of real pedestrians in the video being unavailable; also the distribution of the groups in the scene may vary dynamically. We therefore need to detect and track real pedestrians on each frame of the video to acquire their distribution and motion information. We save this information by an efficient data structure, called environment grid. During the way of a virtual pedestrian, the respective agent frequently emits the detection rays through the environment cells to find the situation of the real pedestrians ahead of him and adjust the original path if necessary. Virtual pedestrians are merged into the video finally with the occlusion between virtual characters and the real pedestrians correctly presented. Experiment results on several scenarios demonstrate the effectiveness of the proposed approach. 相似文献
87.
Jiading Gai Nady Obeid Joseph L. Holtrop Xiao-Long Wu Fan Lam Maojing Fu Justin P. Haldar Wen-mei W. Hwu Zhi-Pei Liang Bradley P. Sutton 《Journal of Parallel and Distributed Computing》2013
Several recent methods have been proposed to obtain significant speed-ups in MRI image reconstruction by leveraging the computational power of GPUs. Previously, we implemented a GPU-based image reconstruction technique called the Illinois Massively Parallel Acquisition Toolkit for Image reconstruction with ENhanced Throughput in MRI (IMPATIENT MRI) for reconstructing data collected along arbitrary 3D trajectories. In this paper, we improve IMPATIENT by removing computational bottlenecks by using a gridding approach to accelerate the computation of various data structures needed by the previous routine. Further, we enhance the routine with capabilities for off-resonance correction and multi-sensor parallel imaging reconstruction. Through implementation of optimized gridding into our iterative reconstruction scheme, speed-ups of more than a factor of 200 are provided in the improved GPU implementation compared to the previous accelerated GPU code. 相似文献
88.
89.
将干海带在碳酸钠溶液中熬煮,滤液酸化并用双氧水氧化,采用电位滴定法控制氧化析碘过程;以低沸点有机溶剂为萃取剂,采用低温减压分离方法,实现有机溶剂和单质碘的分离,得到的碘收率较高(62.5%),可用差量法称量。探索了滤液pH、双氧水浓度和萃取溶剂对实验结果的影响。分别采用碘量法和分光光度法检验了提取碘的纯度。研究结果表明:滤液pH为2.5~3.5时,用质量分数为2%的双氧水氧化析碘结果比较理想;与二氯甲烷相比,无水乙醚萃取含I2水溶液效率更高。碘量法和分光光度法测定数据较为吻合,都可以用来测定水溶液的碘含量。 相似文献
90.
本文提出一种新的基于α稳定分布噪声环境下的自适应滤波算法,这种算法针对变步长自适应滤波算法收敛速度和稳态误差相矛盾的不足,建立了步长μ(n)与误差信号e(n)之间的新的非线性函数关系。该函数能够削弱输入端不相关α稳定分布噪声对步长调整的影响,更好地解决稳态误差与收敛时间之间的矛盾。通过系统辨识仿真结果表明,新的算法α对稳定分布下的尖峰脉冲噪声有较强的韧性,比传统的NLMP算法有更快的参数辨识速度和更小的稳态误差,同时还具有很好地跟踪多时变系统的能力。 相似文献