Design,Synthesis and Biological Activities of Novel Anthranilic Diamides Containing Dihydroisoxazoline and Isoxazole

Anthranilic diamides are one of the most important classes of modern agrochemical insecticides. To discover new structures with higher activity, lower toxicity and lower residue, a series of novel anthranilic diamides containing dihydroisoxazoline and isoxazole was designed and synthesized. Their structures were characterized by means of melting points, proton nuclear magnetic resonance(¹H NMR), ¹³C NMR and high resolution mass spec-trometry(HRMS). According to the bioassay data, it was found that some of the title compounds exhibit moderate insecticidal activity and good antifungal activity. In particularly, compound 15b with a concentration of 50 mg/L shows a lethality rate of 60.0% against Mythimna separata Walker and a lethality rate of 50.0% against Culex pipiens pallens with a concentration of 1mg/L. Moreover, compound 15b showed good antifungal activities(58.8%, 77.1%, 70.7%, 55.3%, 60.7%, 65.4%) when against all the tested fungi(Cercospora arachidicola Hori, Physalospora piricola, Rhizoctonia cerealis, Bipolaris maydis, Watermelon anthracnose, Fusarium moniliforme). The effects of compounds 14h, 14j and 15b on the concentration of intracellular calcium ion([Ca²⁺]_i) in the central neurons of Mythimna separate Walker were well investigated via calcium imaging technique. The results demonstrate that the novel compounds can elevate the calcium concentration in the neurons, denoting that some new structures are potential modulators of the insect ryanodine receptor(RyR).     

火炮用PCrMo钢激光熔覆MoS2润滑涂层摩擦学性能研究

PCrMo钢是导致火炮系统故障的磨损失效零部件主要材料.为了提高零部件的寿命,将固体润滑技术引入火炮抗磨减磨设计中.选取8 ～ 10 μm和3～5 μm两种粒度下二硫化钼作为固体润滑材料,采用激光熔覆工艺在PCrMo钢试样表面制备润滑涂层.通过对涂层宏观性能表征,发现粒度小的涂层熔覆厚度较好;采用扫描电镜和能谱仪分别对涂层表面、剖面微观形貌和化学成分进行分析,发现涂层表面有凹坑产生,且凹坑中氧的含量明显高于光滑表面;涂层剖面与基体结合处存在一定的缝隙,涂层元素与基体元素发生了熔渗.进一步开展的摩擦磨损试验表明:与PCrMo钢裸基材试样相比,两种粒度下润滑涂层试样摩擦系数和磨损量皆降低,磨损量分别为14.84％和42.01％,其中大粒度下涂层摩擦性能较优.二硫化钼润滑涂层起到了很好的润滑效果,可以作为火炮磨损零部件减磨的有效手段.     

Ring Enlargement and Sulfur‐Transfer Processes in SiO2‐Catalyzed Reactions of Thiocarbonyl Compounds with Optically Active Oxiranes

The reactions of 1,3‐dioxolane‐2‐thione ( 3 ) with (S)‐2‐methyloxirane ((S)‐ 1 ) and with (R)‐2‐phenyloxirane ((R)‐ 2 ) in the presence of SiO₂ in anhydrous dichloroalkanes led to the optically active spirocyclic 1,3‐oxathiolanes 8 with Me at C(7) and 9 with Ph at C(8), respectively (Schemes 2 and 3). The analogous reaction of 1,3‐dimethylimidazolidine‐2‐thione ( 4a ) with (R)‐ 2 yielded stereoselectively (S)‐2‐phenylthiirane ((S)‐ 10 ) in 83% yield and 97% ee together with 1,3‐dimethylimidazolidin‐2‐one ( 11a ). In the cases of 3‐phenyloxazolidine‐2‐thione ( 4b ) and 3‐phenylthiazolidine‐2‐thione ( 4c ), the reaction with (RS)‐ 2 yielded the racemic thiirane (RS)‐ 10 , and the corresponding carbonyl compounds 11b and 11c (Scheme 4 and Table 1). The analogous reaction of 4a with 1,2‐epoxycyclohexane (= 7‐oxabicyclo[4.1.0]heptane; 7 ) afforded thiirane 12 and the corresponding carbonyl compound 11a (Scheme 5). On the other hand, the BF₃‐catalyzed reaction of imidazolidine‐2‐thione ( 5 ) with (RS)‐ 2 yielded the imidazolidine‐2‐thione derivative 13 almost quantitatively (Scheme 6). In a refluxing xylene solution, 1,3‐diacetylimidazolidine‐2‐thione ( 6 ) and (RS)‐ 2 reacted to give two imidazolidine‐2‐thione derivatives, 13 and 14 (Scheme 7). The structures of 13 and 14 were established by X‐ray crystallography (Fig.).     

孔隙度数值反演计算

由渗流微分方程定解问题和Peaceman方程给出了网格压力、井底压力对网格孔隙度的导数,利用三维渗流方程压强数值解计算井底压力对网格孔隙度的导数;采用共轭梯度法实现孔隙度均匀(或分块均匀)分布油藏模型的反演计算.算例表明,经过8~10次迭代后反演结果与真值的最大相对误差在0.03%以内,反演收敛于真值.     

宽角度X射线超反射镜的设计

阐述了一种新的X射线超反射镜的设计方法.该方法将Frensnel反射系数公式和单纯形调优法相结合,可以设计出满足不同要求的X射线超反射镜.依据周期多层膜确定膜层数,给出了一种确定超反射镜膜层数的方法.设计了在铜(Cu)的Kα线下,具有不同掠入射角宽度的多种钨(W)/碳(C)超反射镜.设计中考虑了多层膜结构的界面粗糙度和相互扩散对多层膜反射性能的影响,并做了模拟计算.实验结果表明:用这种方法设计X射线超反射镜优于现有的其他方法.     

双折射光纤传输特性与偏振状态的实验研究

本文对两种不同结构双折射光纤的偏光特性进行了实验研究．测试了它们传输损耗与入射光偏振状态的关系及光纤不同曲率对传输导模的影响．给出了测试装置和测试原理，并对结果进行了分析．     

An Information-theoretic Approach to the Effective Usage of Auxiliary Information from Survey Data

In this paper, we propose an information-theoretic approach to the effective usage of auxiliary information from survey data, which is suitable for both simple and complex survey data. Our estimator under simple random sampling without replacement will be consistent and asymptotically normal. We show that the resulting estimates have smaller asymptotic variances than the usual estimates which do not use auxiliary information. For more complex survey designs, the resulting estimator is in essence asymptotically equivalent to a pseudo empirical likelihood estimator. Results of a limited simulation study show that the proposed estimators perform well among a number of competitors.     

用XPS振起伴峰表征聚苯醚酮的辐射凝胶化剂量

X-射线光电子能谱(XPS)振起(Shake-Up)伴峰主要是伴随主光电子的电离所导致的最高占有轨道到最低未占有轨道电子跃迁的结果.Carlson及Clark的工作声明这种振起伴峰是某些共轭π电子体系的表征,振起伴峰的相对强度与π电子共轭情况有关。 含酚酞侧基聚芳醚酮(PEK-C)是一种新型耐高温工程塑料,其主侧链均带苯环:     

关于一类抛物型Monge-Ampère方程解的注记

本文讨论如下抛物型Monge-Ampere方程的第一初边值问题-ut+det1/n D2u=g(χ,t),(χ,t)∈Q=Ω×(0,T),u= (χ,t),(χ,t)∈ pQ,其中Ω为Rn中有界凸集.证明了在更一般的结构条件下[3,7]的结果仍然成立.证明中重要的一点是在Rn × R中非柱型域上“冻结问题”的可解性.     

On the beltram I flows

To illustrate the general properties of the Beltrami flows, a new sufficient and necessary condition of the general solution of the Beltrami flows has been given, on whose basis some sufficient and necessary conditions and sufficient conditions in literature are unified. The advantages of the new expressions are that one may get solutions of Beltrami flows with constant proportional factors which satisfy some given asymptotic decaying conditions at infinity. Finally, we find a class of spherical vortices of Beltrami flows, where the motion trajectories of the fluid particles are confined within a sphere or two adjacent concentric spherical shells. We find that the superpositions of the spherical vortices of the same order with different polar axes may produce chaotic trajectories. The project is supported by the National Foundamental Research Programme of State Commission of Sciences and Technology.