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Der Freie Zahnarzt - Die chemomechanische Aufbereitung des Wurzelkanalsystems stellt den wichtigsten Bestandteil der endodontischen Therapie dar und beeinflusst den Erfolg der Behandlung... 相似文献
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Janne Pleidrup Andersen Liselotte R. Norup Tina S. Dalgaard Lisa Rothwell Pete Kaiser Anders Permin 《Avian pathology》2013,42(3):276-282
In chickens, the nematode Ascaridia galli is found with prevalences of up to 100% causing economic losses to farmers. No avian nematode vaccines have yet been developed and detailed knowledge about the chicken immune response towards A. galli is therefore of great importance. The objective of this study was to evaluate the induction of protective immune responses to A. galli soluble antigen by different immunization routes. Chickens were immunized with a crude extract of A. galli via an oral or intra-muscular route using cholera toxin B subunit as adjuvant and subsequently challenged with A. galli. Only chickens immunized via the intra-muscular route developed a specific A. galli antibody response. Frequencies of γδ T cells in spleen were higher 7 days after the first immunization in both groups but only significantly so in the intra-muscularly immunized group. In addition, systemic immunization had an effect on both Th1 and Th2 cytokines in caecal tonsils and Meckel's diverticulum. Thus both humoral and cellular immune responses are inducible by soluble A. galli antigen, but in this study no protection against the parasite was achieved. 相似文献
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Simon G. Danby Ph.D. Tareq AlEnezi M.D. Amani Sultan M.D. Tina Lavender Ph.D. RM R.G.N. John Chittock B.Sc. Kirsty Brown B.Sc. Michael J. Cork Ph.D. F.R.C.P. 《Pediatric dermatology》2013,30(1):42-50
Natural oils are advocated and used throughout the world as part of neonatal skin care, but there is an absence of evidence to support this practice. The goal of the current study was to ascertain the effect of olive oil and sunflower seed oil on the biophysical properties of the skin. Nineteen adult volunteers with and without a history of atopic dermatitis were recruited into two randomized forearm‐controlled mechanistic studies. The first cohort applied six drops of olive oil to one forearm twice daily for 5 weeks. The second cohort applied six drops of olive oil to one forearm and six drops of sunflower seed oil to the other twice daily for 4 weeks. The effect of the treatments was evaluated by determining stratum corneum integrity and cohesion, intercorneocyte cohesion, moisturization, skin‐surface pH, and erythema. Topical application of olive oil for 4 weeks caused a significant reduction in stratum corneum integrity and induced mild erythema in volunteers with and without a history of atopic dermatitis. Sunflower seed oil preserved stratum corneum integrity, did not cause erythema, and improved hydration in the same volunteers. In contrast to sunflower seed oil, topical treatment with olive oil significantly damages the skin barrier, and therefore has the potential to promote the development of, and exacerbate existing, atopic dermatitis. The use of olive oil for the treatment of dry skin and infant massage should therefore be discouraged. These findings challenge the unfounded belief that all natural oils are beneficial for the skin and highlight the need for further research. 相似文献
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Iris Schrijver Nazneen Aziz Daniel H. Farkas Manohar Furtado Andrea Ferreira Gonzalez Timothy C. Greiner Wayne W. Grody Tina Hambuch Lisa Kalman Jeffrey A. Kant Roger D. Klein Debra G.B. Leonard Ira M. Lubin Rong Mao Narasimhan Nagan Victoria M. Pratt Mark E. Sobel Karl V. Voelkerding Jane S. Gibson 《The Journal of molecular diagnostics : JMD》2012,14(6):525-540
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Monica Terenziani MD Paolo D'Angelo MD Gianni Bisogno MD Renata Boldrini MD Giovanni Cecchetto MD Paola Collini MD Massimo Conte MD Tina De Laurentis MD Ilaria Ilari MD Paolo Indolfi MD Alessandro Inserra MD Luigi Piva MD Fortunato Siracusa MD Filippo Spreafico MD Paolo Tamaro MD Margherita Lo Curto MD 《Pediatric blood & cancer》2010,54(4):532-537
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