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After months of confronting COVID-19 pandemic, several countries, including Saudi Arabia, have recently approved newly developed vaccines to prevent COVID-19 infection. With the new technology utilized to develop some vaccines, questions arise about their long-term safety. To provide rapid response to emerging safety issues, robust surveillance programs that provide near real-time analysis of vaccines effects are required. Saudi Arabia has a well-established passive pharmacovigilance system that monitors drugs and vaccines safety. However, recent development in health digitalization in Saudi Arabia may provide a unique opportunity to harvest existing resources to generate high-quality evidence. This commentary provides an overview of the available systems that can be utilized to monitor the COVID-19 vaccines’ safety and discusses opportunities for data integration to improve data quality and generate real-world evidence on COVID-19 vaccine safety. 相似文献
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Yasmine G. Saad Hadeel M. Seif El Dein Yasmine A. Mansi Rania H. Hashem 《The Egyptian Journal of Radiology and Nuclear Medicine》2018,49(3):755-763
Aim of work
To evaluate the role of ultrasound and color Doppler in diagnoses and predicting the outcome of necrotising enterocolitis patients at neonatal ICU.Subjects and methods
Thirty neonates clinically diagnosed with NEC were examined, 51 ultrasound examinations were done including color Doppler sonography and findings were compared with laboratory data, clinical picture, staging, abdominal radiography and patient's outcome.Results
Bloody stools and abdominal discoloration correlated with highest risk, low PH and neutropenia and increased DAAS score matched poor outcome. echoegnic free fluid, thin bowel wall, absent wall perfusion, aprestalsis, dilated anechoic bowel, increased bowel perfusion and pneumatoses intestinalis matched adverse outcome. sonographic signs of pneumatoses intestinalis interrelated with radiographic signs.Conclusion
US was found to be highly sensitive and specific in diagnosing, staging and predicting the outcome of NEC patients, based on group of findings that were categorized per their risk ratio and correlated with outcome. 相似文献105.
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Feras AlMofreh DDS Sami AlOtaibi Mohamed Jaber Khaled Bishawi DDS Ahmed AlShanably DDS Faris AlMutairi 《Saudi Dental Journal》2021,33(8):805-812
ObjectivesIdentify specific maxillofacial trauma patterns associated with cervical spine injuries.MethodsThe protocol was developed according to (PRISMA-P) and was admitted to PROSPERO under accreditation code #CRD42020177816. Furthermore, the reporting of the present SR was conducted based on the PRISMA checklist.ResultsOf the 1,407,750 patients recorded, a total of 115,997 patients (12.13%) had MFF with an associated CSI with a gender proportion (M:F) of 3.63:1 respectively. Motor vehicle accident was the most common cause of the combined Maxillofacial Trauma (MFT) and CSI. The most common CSI location was at the C2, followed by the C5 cervical spines. The most common location of a maxillofacial fracture resulting in a CSI was the mandible.ConclusionThe incidence of the association of CSIs with MFT has been low (12.13%). Nevertheless, in cases of an isolated mandibular trauma due to a severe blow presenting with a low Glasgow Coma Scale, maxillofacial surgeons should be at a high alert of an associated CSI. 相似文献
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In this study, the biaxial flexural strength (BFS) and fractography of high/ultra-translucent monolithic zirconia ceramics subjected to different mechanical surface pretreatments were evaluated. A total of 108 disc-shaped samples (12 mm diameter, 1.2 mm thickness) of three zirconia materials (5Y-ZP KATANA Zirconia UTML (ML), 3Y-TZP DD Bio ZX2 (DB), and 5Y-ZP DD cube X2 (DC)) were used. The BFS was investigated after subjecting the samples to surface treatment using air abrasion particles of two types (aluminum oxide or glass microbeads). The data were analyzed using two-way analysis of variance, followed by Scheffe’s post hoc test for multiple comparisons. The mean ± standard deviation BFS for DB was highest after treatment with 50 µm Al2O3 (1626.05 ± 31.9 MPa), with lower values being observed following treatment with 50 µm glass microbeads (1399.53 ± 24.2 MPa) and in the control sample (1198.51 ± 21.1 MPa). The mean ± standard deviation (SD) BFSs for DC and ML were the highest in the control groups. Surface air abrasion with 50 µm Al2O3 particles and 2 bar pressure is recommended for 3Y-TZP translucent zirconia, while no abrasion of 5Y-ZP translucent zirconia ceramic. 相似文献
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Real life Egyptian experience of efficacy and safety of Simeprevir/Sofosbuvir therapy in 6211 chronic HCV genotype IV infected patients 下载免费PDF全文
Rasha Eletreby Wafaa Elakel Mohamed Said Mohamed El Kassas Sameh Seif Tamer Elbaz Maissa El Raziky Siham Abdel Rehim Samy Zaky Rabab Fouad Hadeel Gamal Eldeen Mahmoud Abdo Mohamed Korany Ayman Yosry Magdy El Serafy Manal Hamdy El‐Sayed Yehia ElShazly Imam Waked Wahid Doss Gamal Esmat 《Liver international》2017,37(4):534-541
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