Integrated Direct and Indirect Flood Risk Modeling: Development and Sensitivity Analysis

In this article, we propose an integrated direct and indirect flood risk model for small‐ and large‐scale flood events, allowing for dynamic modeling of total economic losses from a flood event to a full economic recovery. A novel approach is taken that translates direct losses of both capital and labor into production losses using the Cobb‐Douglas production function, aiming at improved consistency in loss accounting. The recovery of the economy is modeled using a hybrid input‐output model and applied to the port region of Rotterdam, using six different flood events (1/10 up to 1/10,000). This procedure allows gaining a better insight regarding the consequences of both high‐ and low‐probability floods. The results show that in terms of expected annual damage, direct losses remain more substantial relative to the indirect losses (approximately 50% larger), but for low‐probability events the indirect losses outweigh the direct losses. Furthermore, we explored parameter uncertainty using a global sensitivity analysis, and varied critical assumptions in the modeling framework related to, among others, flood duration and labor recovery, using a scenario approach. Our findings have two important implications for disaster modelers and practitioners. First, high‐probability events are qualitatively different from low‐probability events in terms of the scale of damages and full recovery period. Second, there are substantial differences in parameter influence between high‐probability and low‐probability flood modeling. These findings suggest that a detailed approach is required when assessing the flood risk for a specific region.     

Values,Perceived Risks and Benefits,and Acceptability of Nuclear Energy

We examined how personal values and perceptions of risks and benefits are associated with the acceptability of nuclear energy (NE). A theoretical model is tested in which beliefs about the risks and benefits of NE mediate the relationship between values and acceptability. The results showed that egoistic values are positively related to the perceived benefits and acceptability of NE. In contrast, altruistic and biospheric values were positively related to the perceived risks of NE. Although it has been argued that NE may help to combat climate change through lower CO₂ emissions, these environmental benefits were not acknowledged by people with strong biospheric values. Furthermore, results confirmed that the more risks respondents perceived, the less they were inclined to accept NE. In contrast, the more a person believed that NE has beneficial consequences, the more acceptable NE was. Finally, as expected, perceived risks and benefits were found to partly mediate the relationship between personal values and acceptability. We discuss the theoretical and practical implications of these findings.     

Review and Assessment of Poliovirus Immunity and Transmission: Synthesis of Knowledge Gaps and Identification of Research Needs

With the intensifying global efforts to eradicate wild polioviruses, policymakers face complex decisions related to achieving eradication and managing posteradication risks. These decisions and the expanding use of inactivated poliovirus vaccine (IPV) trigger renewed interest in poliovirus immunity, particularly the role of mucosal immunity in the transmission of polioviruses. Sustained high population immunity to poliovirus transmission represents a key prerequisite to eradication, but poliovirus immunity and transmission remain poorly understood despite decades of studies. In April 2010, the U.S. Centers for Disease Control and Prevention convened an international group of experts on poliovirus immunology and virology to review the literature relevant for modeling poliovirus transmission, develop a consensus about related uncertainties, and identify research needs. This article synthesizes the quantitative assessments and research needs identified during the process. Limitations in the evidence from oral poliovirus vaccine (OPV) challenge studies and other relevant data led to differences in expert assessments, indicating the need for additional data, particularly in several priority areas for research: (1) the ability of IPV‐induced immunity to prevent or reduce excretion and affect transmission, (2) the impact of waning immunity on the probability and extent of poliovirus excretion, (3) the relationship between the concentration of poliovirus excreted and infectiousness to others in different settings, and (4) the relative role of fecal‐oral versus oropharyngeal transmission. This assessment of current knowledge supports the immediate conduct of additional studies to address the gaps.     

Preeradication Vaccine Policy Options for Poliovirus Infection and Disease Control

With the circulation of wild poliovirus (WPV) types 1 and 3 continuing more than a decade after the original goal of eradicating all three types of WPVs by 2000, policymakers consider many immunization options as they strive to stop transmission in the remaining endemic and outbreak areas and prevent reintroductions of live polioviruses into nonendemic areas. While polio vaccination choices may appear simple, our analysis of current options shows remarkable complexity. We offer important context for current and future polio vaccine decisions and policy analyses by developing decision trees that clearly identify potential options currently used by countries as they evaluate national polio vaccine choices. Based on a comprehensive review of the literature we (1) identify the current vaccination options that national health leaders consider for polio vaccination, (2) characterize current practices and factors that appear to influence national and international choices, and (3) assess the evidence of vaccine effectiveness considering sources of variability between countries and uncertainties associated with limitations of the data. With low numbers of cases occurring globally, the management of polio risks might seem like a relatively low priority, but stopping live poliovirus circulation requires making proactive and intentional choices to manage population immunity in the remaining endemic areas and to prevent reestablishment in nonendemic areas. Our analysis shows remarkable variability in the current national polio vaccine product choices and schedules, with combination vaccine options containing inactivated poliovirus vaccine and different formulations of oral poliovirus vaccine making choices increasingly difficult for national health leaders.     

Development of simulation-based production execution system in a shipyard: a case study for a panel block assembly shop

The management of a panel block shop in a shipyard is a complex process that entails the largest amount of work and in which many decisions are involved. Shipbuilders have considered the process as a bottleneck since every panel for every ship must be processed through the shop. The objective of this research is to carry out a materials flow analysis to maximise process productivity and to place simulation optimisation technology in the hands of decision makers, such as production planners and supervisors. In this article, a production execution planning system is proposed for panel block operations utilising discrete-event simulation and simulated annealing. The simulation model was validated using a real production scenario and the comparison showed a very favourable agreement between the actual panel shop and the simulation model. The proposed system supports production planners by general dispatching rules and optimisation to make better scheduling decisions on the shop floor. The system will provide a complete schedule that is at least as clear and accurate as any schedule currently obtained.     

Metabolic impact of shift work

In developing countries, shift work represents a considerable contingent workforce. Recently, studies have shown that overweight and obesity are more prevalent in shift workers than day workers. In addition, shift work has been associated with a higher propensity for the development of many metabolic disorders, such as insulin resistance, diabetes, dislipidemias and metabolic syndrome. Recent data have pointed that decrease of the sleep time, desynchronization of circadian rhythm and alteration of environmental aspects are the main factors related to such problems. Shortened or disturbed sleep is among the most common health-related effects of shift work. The plausible physiological and biological mechanisms are related to the activation of the autonomic nervous system, inflammation, changes in lipid and glucose metabolism, and related changes in the risk for atherosclerosis, metabolic syndrome, and type II diabetes. The present review will discuss the impact of shift work on obesity and metabolic disorders and how disruption of sleep and circadian misalignment may contribute to these metabolic dysfunctions.     

Ergonomic evaluation of the preparation of cuttings and minicuttings for eucalyptus seedling production, with the use of scissors

This study was conducted in a nursery for eucalyptus seedling production in a forest Company, located in the southern state of Bahia, Brazil. It aimed to evaluate the ergonomic conditions of the preparation of cuttings and mini-cuttings with scissors for Eucalyptus seedling production to increase well-being, satisfaction and safety and minimizing the occurrence of occupational diseases, also improving the process efficiency and final product quality. Environmental conditions, levels of noise, postures, RSI risk and physical workload were assessed. The environmental conditions complied with the recommended norms, except at certain times of day, when workers should make compensation breaks. The workers that collect minicuttings presented postures classified as normal by OWAS. On the other hand, the posture of workers dealing with cutting preparation requires corrections in a short run. The workers were subjected to moderate RSI risk due to the high degree of repeatability found. The physical workload was classified as mild, with no need for ergonomic interventions.