Monitoring manufacturing system availability

The monitoring of production line availability on a day-to-day basis and for continuous improvement is approached from a control charting point of view. Control limits are developed along with the length of time between monitoring periods to control accuracy. This provides a convenient way to monitor the availability measure at any desired level of accuracy.     

A Procedure to Estimate the Population Mean In Random Effects Models

A general procedure for estimating the population mean in random effects models of the nested and/of classification type is considered. The suggested estimator is unbiased and consistent (with respect to the structure of the experimental design). It is also optimal with respect to a particular quadratic, location-sensitive criterion. Finally, for experimental designs which contain a certain degree of structural balance, the suggested estimator coincides with the sample mean.     

Localization of trehalose in partially hydrated DOPC bilayers: insights into cryoprotective mechanisms

Trehalose, a natural disaccharide with bioprotective properties, is widely recognized for its ability to preserve biological membranes during freezing and dehydration events. Despite debate over the molecular mechanisms by which this is achieved, and that different mechanisms imply quite different distributions of trehalose molecules with respect to the bilayer, there are no direct experimental data describing the location of trehalose within lipid bilayer membrane systems during dehydration. Here, we use neutron membrane diffraction to conclusively show that the trehalose distribution in a dioleoylphosphatidylcholine (DOPC) system follows a Gaussian profile centred in the water layer between bilayers. The absence of any preference for localizing near the lipid headgroups of the bilayers indicates that the bioprotective effects of trehalose at physiologically relevant concentrations are the result of non-specific mechanisms that do not rely on direct interactions with the lipid headgroups.     

Cognitive Correlates of Improvised Behaviour in Disaster Response: the Cases of the Murrah Building and the World Trade Center

While emergency response actions are known to range from conventional to improvised, less is known about the thinking processes that underlie these actions. This paper presents a statistical analysis of cognition and behaviour reported by police personnel who responded to two significant US disasters: the 1995 bombing of the Murrah Building in Oklahoma City and the 2001 attack on the World Trade Center in New York City. The results suggest the prominence of conventional behaviour coupled with cognitive processes closely tied to recognition, and of improvised behaviours that are linked to more explicit reasoning processes. The results underscore the value of exploring cognitive foundations of both conventional and improvised behaviours to enrich understanding of human response to disaster.     

Testing Einstein's faux formula: fast computers+slow humans=creative brilliance

An experiment was designed for the purpose of testing the proposition that creative decision-making can be greatly improved by making use of the personal computer to solve a set of word anagrams serving as hints to a surprise phrase. The authors hypothesised that the experimental condition of students using various unscramble word jumble websites would significantly outperform the control group of students who attempted to unscramble the words and solve the surprise answer by hand. Results were mixed and the authors conclude that certain types of creative problem solving exercises might benefit more from the innate abilities and talents of the participants rather than the speed and accuracy of the computer.     

A simple and effective heuristic for the resource constrained project scheduling problem

This paper investigates the development and application of a simple heuristic to the resource constrained project scheduling problem (RCPSP). This computer heuristic, which is based on the COMSOAL heuristic, constructs a feasible solution at each iteration and chooses the best solution of several iterations. Although COMSOAL was originally a solution approach for the assembly-line balancing problem, it can be extended to provide solutions to the resource allocation problem. The Modified COMSOAL technique presented in this paper uses priority schemes intermittently with a random selection technique. This hybrid of randomness and priority scheme allows a good solution to be found quickly while not being forced into the same solution at each iteration. Several different priority schemes are examined within this research. The COMSOAL heuristic modified with the priority schemes heuristic was tested on several established test sets and the solution values are compared with both known optimal values and the results of several other resource allocation heuristics. In the vast majority of cases, the Modified COMSOAL heuristic outperformed the other heuristics in terms of both average and maximum percentage difference from optimal. The Modified COMSOAL heuristic seems to have several advantages over other RCPSP heuristics in that it is easy to understand, easy to implement, and achieves good results.     

Contact lenses and the rate of evaporation measured in vitro; the influence of wear,squalene and wax

Accelerated evaporation of tears may contribute to dry eye symptoms. It is not clear whether contact lenses decrease or increase the rate of evaporation of tears. In this study, the rates of evaporation through contact lenses (ERTCL) were measured in vitro to gain insight to this question. Contact lenses were equilibrated with various solutions to determine if they influenced ERTCL in vitro. ERTCL was measured gravimetrically. ERTCL measured in vitro for used contact lenses was about 20% faster than for buffer alone suggesting that natural tear components bound to the lenses changed the ERTCL. One natural tear component that binds to contact lenses is waxes. Equilibration of contact lenses with wax increased the ERTCL by about 30% suggesting that waxes might potentially increase ERTCL in vivo. Squalene, found in sebum and possibly meibum was infused into the contact lenses as a step toward decreasing the ERTCL. Squalene decreased ERTCL by over 60% in vitro. Soaking a contact lens in DuraSite^® with benzalkonium chloride (BAK) did not alter the ERTCL. ERTCL were about 40% higher than the evaporation rate of DuraSite^® alone or without BAK.In addition to lowering the ERTCL, the squalene in contact lenses could be a source of terpenoids to replace the terpenoids deficient in patients with MGD. If the ERTCL could be minimized in vivo, contact lenses could potentially be used to relieve dry eye symptoms in patients with evaporative dry eye.     

Adult aging effects on semantic and episodic priming in word recognition.

Two experiments compared automatic semantic and episodic priming effects in adult aging. In the 1st experiment, target words were semantically primed; in the 2nd experiment, targets were primed by repetition of semantically unrelated words. Both experiments involved a pronunciation task with response signals at fixed times following target onset. Consequently, priming was measured as improvement in the percentage of correct responses. Priming was also calculated with speed–accuracy measures of intercept and slope. Both types of priming effect were significant in the percentage correct and slope measures, but no age group differences were found. Furthermore, the magnitudes of the priming effects were equivalent. The age-resistant nature of semantic and episodic priming, as well as evidence for a common theoretical mechanism, is discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)