"Comment on 'Articulation of values'": Response to Cochran (1988).

We respond to Cochran's critique of our 1986 study, which was in part a replication of Cochran's original grid methodology for the study of career values. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Tabula Rasa: Pitfalls and Possibilities with Clean Slate Initiatives

If an IT system is so so hopelessly and fundamentally flawed that there's no practical way to address its deficiencies one by one, a clean slate initiative might be the only way out of the swamp. The key is to make sure the drivers are sound, the process is retrospective, the solution is robust, and expectations are realistic.     

Theory, subjectivity and bias: Can there be a future?

Argues that most theorists in the realm of psychotherapy have not behaved like detached, impartial scientists but like itinerant proselytizers. In more recent times, a bias of a different kind has entered the field. "Hermeneutics," "social constructionism," and "postpositivism," although by no means synonymous, all offer a worldview that differs from established tenets of scientific data collection and objective measurement. These complex intellectual traditions emphasize that recordings of reality are mere projections and creations of the observer. The double impact of subjectivity and bias renders little hope for an optimistic future. A possible solution lies in the expansion of a broad-based social and cognitive learning theory that incorporates testable notions and empirically based clinical observations. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Vollständige Beschreibung der Spannungs-Dehnungs-Kurven mit Hooke-Gerade,Fließhorizontale und Verfestigungsklothoide

Es werden die experimentellen und numerischen Ergebnisse dargelegt, um die gesamte Spannungs-Dehnungs-Kurve des Zugversuches mit sechs Kennwerten zu beschreiben. Dies sind: Elastizitätsmodul, Streckgrenze, Fließdehnung, Zugfestigkeit, Gleichmaßdehnung und Verfestigungsmodul. Dadurch werden auch im überelastischen Bereich numerische Beziehungen möglich zwischen: Verformungen und Spannungen, Dehngrenzen, Tangenten-Modulen und Arbeitsvermögen. Die Beziehungen erweitern die Ermittlung von Last- und Eigenspannungen, und die Berechnungen beim plastischen Umformen, beim Traglastverfahren und beim Messen von Kerbspannungen.     

Localization of putative tumor suppressor loci by genome-wide allelotyping in human pancreatic endocrine tumors

Only two tumor suppressor gene loci, one on 3p25 and the MEN1 gene on 11q13, have thus far been implicated in the pathogenesis of sporadic human pancreatic endocrine tumors (PETs). A genome-wide allelotyping study of 28 human PETs was undertaken to identify other potential tumor suppressor gene loci. In addition to those on chromosomes 3p and 11q, frequent allelic deletions were identified on 3q (32%), 11p (36%), 16p (36%), and 22q (29%). Finer deletion mapping studies localized the smallest regions of common deletion to 3q27, 11p13, and 16p12.3-13.11. Potential candidate genes at these loci include WT1 (11p13), TSC2 (16p13), and NF2 (22q12), but no known tumor suppressor gene localizes to 3q27. The mean fractional allelic loss among these human PETs is 0.126, and no correlation was observed between allelic loss and clinical parameters, including age, sex, hormonal subtype, and disease stage. These findings highlight novel locations of tumor suppressor gene loci that contribute to the pathogenesis of human PETs, and several of these on 3p, 3q, and 22q are syntenic with loci on mouse chromosomes 9 and 16 that are implicated in a murine transgenic model of PETs.     

On perspectives, theories, models, and friends: A reply to the relationalists.

The authors respond to the "relational" issue of Psychoanalytic Psychology (PP; Vol. 12, No. 1) and support Karol Marshall's remonstration about the need to clarify what exactly the category relational refers to. It is noteworthy that in this issue of PP the relational thinkers do not engage the specific topics of our essay. The author's article attempted to review the most comprehensive relational thinkers of that time across theoretical variables. Relationalists have begun to spell out the technical consequences of their perspective in recent discussions of neutrality, authority, and self-disclosure, among other issues. This is a useful trend in the relational literature, and we hope it continues. We are concerned, however, that the relational thinkers writing in this issue tend to dismiss the contributions to PP 12(1) because the perspectives presented there did not satisfy the relationalist vision of how scientific exchange should be undertaken. Although we feel that it is important for emerging points of view to be able to elaborate assumptions, constructs, and principles within their own framework and in their own way, constructive dialogue, much less a comparative analysis of the contributions and limitations of different points of view, requires that we have some common ground. (PsycINFO Database Record (c) 2010 APA, all rights reserved)