全文获取类型
收费全文 | 72637篇 |
免费 | 5241篇 |
国内免费 | 483篇 |
学科分类
医药卫生 | 78361篇 |
出版年
2023年 | 379篇 |
2022年 | 533篇 |
2021年 | 1801篇 |
2020年 | 982篇 |
2019年 | 1603篇 |
2018年 | 1877篇 |
2017年 | 1433篇 |
2016年 | 1585篇 |
2015年 | 2181篇 |
2014年 | 2842篇 |
2013年 | 3457篇 |
2012年 | 5134篇 |
2011年 | 5085篇 |
2010年 | 3075篇 |
2009年 | 2718篇 |
2008年 | 4150篇 |
2007年 | 4150篇 |
2006年 | 4004篇 |
2005年 | 3917篇 |
2004年 | 3560篇 |
2003年 | 3151篇 |
2002年 | 2980篇 |
2001年 | 1779篇 |
2000年 | 1673篇 |
1999年 | 1431篇 |
1998年 | 669篇 |
1997年 | 594篇 |
1996年 | 561篇 |
1995年 | 461篇 |
1994年 | 402篇 |
1993年 | 329篇 |
1992年 | 712篇 |
1991年 | 589篇 |
1990年 | 613篇 |
1989年 | 489篇 |
1988年 | 476篇 |
1987年 | 416篇 |
1986年 | 386篇 |
1985年 | 366篇 |
1984年 | 359篇 |
1983年 | 313篇 |
1982年 | 304篇 |
1981年 | 294篇 |
1980年 | 292篇 |
1979年 | 317篇 |
1978年 | 239篇 |
1977年 | 228篇 |
1976年 | 215篇 |
1974年 | 226篇 |
1972年 | 207篇 |
排序方式: 共有10000条查询结果,搜索用时 765 毫秒
41.
Chi-Chih Hung Jinn-Yuh Guh Mei-Chuan Kuo Yung-Hsiung Lai Hung-Chun Chen 《Nephrology, dialysis, transplantation》2006,21(2):547-548
Sir, Aminoglycoside-induced renal tubular dysfunction could be dividedinto Fanconi-like syndrome (FS) and Bartter-like syndrome (BS)[1]. The risk factors and mechanisms of tubular dysfunctionare little known. Here, we report a case of gentamicin-inducedFS, BS and distal renal tubular acidosis (RTA) and propose thepossible involvement of mitochondria. Case. A 66-year-old Chinese male was admitted because ofpneumonia. 相似文献
42.
The spine, pelvic bones and long bones of the lower extremities are common sites for insufficiency fractures. Cases of sternum insufficiency fractures have been rarely reported in an elderly patient. Insufficiency fracture tends to occur in bones with decreased mechanical strength. It tends to occur in elderly patients, especially in postmenopausal women, with underlying diseases. We describe a case of sternum insufficiency fracture in a patient with rheumatoid arthritis and systemic lupus erythematosus on long-term corticosteroid therapy diagnosed in an emergency setting. Sternum insufficiency fracture is a rare cause of chest pain. This case serves to remind the emergency physician to remain vigilant for other noncardiac and nontraumatic causes of chest pain. If diagnosed accurately, these patients can be discharged and treated as outpatients. 相似文献
43.
44.
Vincent Chung Liang Liu Zhaoxiang Bian Zhongzhen Zhao Wai Leuk Fong Wan Fung Kum Jing Gao Min Li 《Movement disorders》2006,21(10):1709-1715
The objective of this study is to assess the efficacy and safety of herbal medicines (HMs), as a monotherapy or adjunct therapy, compared to placebo or conventional approaches in the treatment of idiopathic Parkinson's disease (PD). We conducted a systematic review of randomized controlled trials from both conventional and alternative medicine sources. Outcome measures were overall improvement, quality of life, reduction of levodopa dose, and adverse events. Nine studies were included, each testing a different HM. Six of the trials had limited internal validity due to major flaws in design, including the lack of proper randomization; insufficient blinding; unclear inclusive criteria in terms of diagnostic criteria, baseline staging, and duration of disease; lack of proper sample size calculation; and insufficient data analysis. Imbalances in gender and ethnicity among the patients in the included trials were observed. No major adverse events emerged, and no specific pattern was detected from the trials describing such data. In addition to major methodological defects, heterogeneity in (1) HM tested, (2) control treatment, and (3) outcome measure hindered in-depth data analysis and synthesis. Current evidence is insufficient to evaluate the efficacy and safety of various HMs. Further studies with improved trial design and reporting, with assessment on cost-effectiveness, quality of life, and qualitative data are warranted. 相似文献
45.
46.
47.
The aim of this study was to design a new intravenous blood–gas exchange device and to estimate the design characteristics
of the device with a dimensionless function by using a substance that can be used instead of bovine blood. In addition, the
characteristics of oxygen transfer were estimated using empirical formulas and the reliability of the equations was ascertained
by comparing their output with an experiment performed using bovine blood. The dimensionless function was derived using distilled
water and bovine blood to estimate the oxygen transfer rate. Using the derived equations, the calculated oxygen transfer rates
for bovine blood and distilled water were similar for Reynolds numbers ranging from 0.7 to 7.0. Therefore, it is possible
to estimate the oxygen transfer rate in bovine blood, which is a non-Newtonian fluid, using distilled water, which is a Newtonian
fluid. Moreover, it was possible to verify the related equations because the oxygen transfer rate could be estimated using
the derived equations, according to the diameters of the various device modules. 相似文献
48.
Eigil Samset Anne Talsma Marius Kintel Ole Jakob Elle Lars Aurdal Henry Hirschberg Erik Fosse 《Computer aided surgery》2002,7(4):187-196
Intraoperative MRI has recently entered the operating room as a new imaging modality. Customized visualization systems might further facilitate the use of this imaging technology. A visualization system for use in the interventional MRI has been developed, providing a virtual environment for surgical navigation using real-time images and for controlling the scanner. The visualization system has customized features for certain clinical applications. A training and testing facility has also been established. The introduction of the visualization system in the interventional MRI overcame several ambiguities and inconsistencies that were previously present, and resulted in a more transparent man-machine interface approach. A pilot study using the software to place cryoprobes in an animal liver showed promising results. Augmentation of real-time MR images with 3D rendering and customized navigation features opens new possibilities in intraoperative MRI. The described system can also be extended to other intraoperative imaging modalities. 相似文献
49.
50.
B. A. Johnson Donald R. Jasinski Gantt P. Galloway Henry Kranzler Robert Weinreib Raymond F. Anton Barbara J. Mason Michael J. Bohn Helen M. Pettinati Richard Rawson Christopher Clyde 《Psychopharmacology》1996,128(2):206-215
Four hundred and twenty-three alcohol dependent subjects were enrolled into a 12-week randomized, double-blind, placebo-controlled
study to determine the safety and efficacy of the 5-HT2 receptor antagonist, ritanserin (2.5 mg/day or 5 mg/day), in reducing alcohol intake and craving. All subjects received 1
week of single-blind placebo prior to randomization into the 11-week double-blind phase. Additionally, all subjects received
weekly individual sessions of manual-guided cognitive-behavioral therapy. Comparing the single-blind period with endpoint,
there was approximately a 23% reduction in drinks/day; 34% fall in the total number of drinking days/week; 22% decrease in
drinks/drinking day; and a 37% diminution in alcohol craving for all treatment groups. All treatment groups experienced a
beneficial clinical outcome as assessed by the Clinical Global Impression Scale. There was, however, no significant difference
between treatment groups on any of these measures of alcohol drinking, craving, or clinical outcome. Subjects were of relatively
high social functioning at baseline, and this did not change significantly during treatment. Treatment groups did not differ
significantly on either medication compliance or reported adverse events. Ritanserin treatment was associated with a dose-related
prolongation of subjects’ QTc interval recording on the electrocardiogram. These results suggest that alcohol dependent subjects
can show marked clinical improvement within a structured alcohol treatment program. These findings do not support an important
role for ritanserin in the treatment of alcohol dependence.
Received: 30 April 1996/Final version: 3 July 1996 相似文献