安宫牛黄丸对脑外伤后血脑屏障损伤及脑水肿作用机制的研究

目的系统地分析安宫牛黄丸对脑外伤后血脑屏障损伤及脑水肿的影响，阐明其作用的分子机制，揭示其开窍醒脑的机理，为临床合理应用及进一步开发利用其治疗脑外伤后所致脑水肿提供依据。方法以Feeney法建立大鼠闭合性脑损伤模型，同绕脑外伤性脑水肿中血脑屏障损伤的主要环节，探讨安宫牛黄丸对脑损伤后脑含水量、BBB通透性以及神经细胞突触数量的影响，系统地分析安宫牛黄丸对血脑屏障损伤及脑水肿的影响，阐明其作用的分子机制，揭示其开窍醒脑的机理。结果与假手术组比较，模型组损伤侧脑含水量及脑皮质EB含量明显增加（P〈0．01）。与模型组比较，安宫牛黄丸组损伤侧脑含水量及脑皮质EB含量明显降低（P〈0．05）。与假手术组比较，模型组损伤侧脑皮质电镜下突触密度显著性降低（P〈0．01），与模型组比较，安宫牛黄丸组损伤侧脑皮质电镜下突触密度明显增加（P〈0．05）。结论安宫牛黄丸可减轻脑水肿、保护血脑屏障、降低毛细血管通透性、提高脑组织对缺血、缺氧的耐受性，从而保护脑组织。     

2%碳酸氢钠用于烧伤患者口腔护理的效果观察

对于烧伤患者,笔者用2%碳酸氢钠溶液进行口腔护理,观察其消除口腔异味,预防口腔炎症的作用,现将结果报告如下. 1 临床资料 选择2006年4月至2009年4月104例中度至重度烧伤患者,随机分为试验组和对照组,每组52例.     

眩晕症的预防及护理

眩晕是目眩和头晕的总称，以眼花、视物不清和昏暗发黑为眩，以视物旋转，或天旋地转视物旋转为晕，因两者常同时并见，故称眩晕。     

全自动血培养仪的临床应用及评价

目的评价全自动血培养仪 (BACTEC90 5 0 )临床应用情况。方法对BACTEC90 5 0全自动血培养仪检测的 4 6 8份标本 ,捡出阳性的时间、细菌种类及阳性率进行了评估。结果BACTEC90 5 0最短检出时间 4小时 ,最长 96小时 ,2 4小时以内阳性率为 6 0 .8% ,4 8小时以内阳性率 82 .4 % ,72小时以内阳性率 94 .1% ,细菌种类 12种 ,阳性 10。 9%。结论BACTEC90 5 0无论从出现阳性的时间、检出细菌种类和阳性率均明显高于本室往年传统方法的结果 ,而且操作简便、结果快速、准确。     

流行性乙型脑炎特异性IgM(ELISA)诊断试剂盒的改进和应用

流行性乙型脑炎夏秋季发病 ,与中毒性痢疾等其他脑部疾患易相混 ,仅靠临床症状诊断 ,可靠性差 ,易延误治疗 ,造成后患。因此 ,我们改进了乙型脑炎特异性IgM诊断试剂盒 ,缩短时间 ,当天抽血 10 0min内即可出报告 ,在短时间内 ,为临床提供可靠依据。     

升主动脉成形术中期效果分析

Objective Reduction ascending aortoplasty is an alternative procdure to the replacement of the ascending aorts in case of ascending aorta dilation. However,its applicabikity is still under debate.This retrospective study was designed to evaluuate the midterm follow-up of unsupported ascending reduction aortoplasty for of the ascending aorta in petients with aortic valve dis- ease.Methods From October ,1996 to April,2007, a total of 54 patients with aortic valve disease and dilatation of the ascending aorta underwent unsupported reduction aortoplasty in combination with aortic valve replacement at our institution The diameter of the ascending aorta was measyred before and early after sugery and then later between 13 and 96 menths [mean (23 ±16)months] posto- perativeiy using echocardiography.Results Two patients were dead with thean overall perioperative mortality rate was of 3.7%. The reduction aortoplasty decreased the diameter of the aorta from (45.77±6.02) mm p～eope～afive]y to (34.67 ～4.81) mm early after surgery (P<0.01). During follow-up, the diameter d aorta increased from (34.67±4.81) mm early after surgery to (37.65± 6.35) mm after a mean follow-up of (23±16) months (P<0.01), including the diameters are greater than > 45 mm within 5 pa- tients. Aortic stenosis and an early postoperative diameter greater than 40 mm m'e independent risk factors for redilatation. Conchusion Because of the unsatisfied midterm follow-up redilation of unsupported reduction aortoplasty for dilation of the ascending aorta with aortic valve disease, this group of patients needs continued intimate fallow-up or even reoperation. The patients of stenosis is the surtable indication for RAA, and it is necessary to reduce the diameter of aorta to be lees than 40 mm to prevent redilation.     

热疗——一种新的抗肿瘤方法记新疆老年病医院热疗专家李振统

由于职业的习惯，我曾走访过多家医院，也采访过众多医疗专家救治病人的感人事迹，但眼前这位专家让我产生一种发自内心的信任。他就是中华医学会新疆分会会员，新疆老年病业务院长，肿瘤热疗专家李振统主治医师。     

介绍一种沥干砂芯滤器内母液的方法

介绍一种沥干砂芯滤器内母液的方法吴瑞英谢碧玉（武警福建省总队医院福州３５００１９）不少医院生产大输液采用不锈钢砂芯滤器进行脱炭。每次生产完毕，滤器内总残留不少母液。如不进行处理是一种大的浪费，而且对溶液的稀释和含量的准确性带来困难。为此，我们在砂芯滤...