基于梯度响应面模型的优化设计

本文主要研究一种梯度响应面模型及其在气动优化设计中的应用. 目前应用广泛的多项式响应面模型是连续可导的, 采用梯度信息构造完全二阶多项式响应面模型, 所需样本数与设计参数个数呈线性关系. 首先通过改进实验设计方法, 快速生成满足精度要求的样本并确定梯度响应面模型. 随后通过函数实验验证梯度响应面模型的精度, 及该模型在多极值函数最值搜索中的有效性. 最后由伴随方法快速求解气动优化设计目标函数的梯度信息, 并开展基于梯度响应面模型和复合形法的叶片压力反设计和效率优化设计. 结果表明: 基于梯度响应面模型的优化方法在全局最优及提高优化效率两方面均有出色表现, 基于该优化方法的气动优化设计能够显著改善叶片的气动性能. 关键词： 气动优化设计 响应面模型 伴随方法 复合形法     

Variational iteration method for solving the mechanism of the Equatorial Eastern Pacific El Nino-Southern Oscillation

A class of coupled system for the E1 Nifio-Southern Oscillation （ENSO） mechanism is studied. Using the method of variational iteration for perturbation theory, the asymptotic expansions of the solution for ENSO model are obtained and the asymptotic behaviour of solution for corresponding problem is considered.     

一维双相介质孔隙率的小波多尺度反演

基于多尺度的思想,将小波多分辨分析和多尺度方法结合,构造了小波多尺度反演方法,并应用于一维双相介质孔隙率的反演.利用小波变换,将原始反问题分解为不同尺度上的一系列子反问题,并按照尺度从粗到细的顺序依次求解.在每一个尺度上,都采用稳定、收敛快的正则化高斯牛顿法求解,次一级尺度上求出的“全局最优解”作为上一级的初始解,依次类推,直到求出原始问题的真正的全局最优解.将小波多尺度方法归结为三种不同算子(分解算子、求解算子、插入算子)的交替应用,给出了小波多尺度反演算法的基本流程图,并推导出当采用Daubechie 关键词： 双相介质 反演 小波多尺度方法 孔隙率     

一个全球气候赤道海气振子模型的变分迭代解法

研究了一个三维赤道海气振子Kelvin波的方程.利用变分迭代解法,得到了对应模型的近似解.变分迭代方法是一个解析方法,得到的解还能够继续进行解析运算. 关键词： 变分迭代 近似解 Kelvin波     

广义Duffing扰动振子随机共振机理的渐近解

利用非线性方法研究了一类广义Duffing扰动方程.首先求得了典型的Duffing方程的解.然后利用泛函广义变分迭代原理得到了广义Duffing扰动振子随机共振机理的近似解,并论述了解的一致有效性.     

β沸石固定酶修饰四氰基醌二甲烷电流型葡萄糖传感器的研究

本文介绍了一种新型的酶传感器, 首次以具有一定规整结构的β沸石固定酶, 以7, 7', 8, 8'-四氰基醌二甲烷作为电子传递媒介体,研制成葡萄糖传感器, 运用傅利叶变换红外光谱研究了β沸石与葡萄糖氧化酶之间的相互作用, 通过载体孔径分布和等电点的测定, 研究了载体的孔结构及表面酸性质对酶吸附的影响规律, 并对电极的制备条件和响应性能进行了优化。     

材料类专业选修课教学改革——柔性材料与器件课程

为进一步改善教学效果、提高教学质量,通过问卷调查的方式,分析材料类专业选修课现存问题及原因,并提出教学改革方向,包括明晰学生的选课目的、动态调整教学内容、多重教学模式提高师生互动和多角度考核方式等提高学生能力素质达成情况。本文以柔性材料与器件课程为例,有针对性地提出了教学内容、教学形式、考核方式等3个方面的具体改进建议和措施,在此基础上总结和完善了面向材料类专业选修课的可行有效对策。     

A high-performance SNP panel developed by machine-learning approaches for characterizing genetic differences of Southern and Northern Han Chinese,Korean, and Japanese individuals

Population stratification analyses targeting genetically closely related East Asians have revealed that distinguishable differentiation exists between Han Chinese, Korean, and Japanese individuals, as well as between southern (S-) and northern (N-) Han Chinese. Previous studies offer a number of choices for ancestry informative single nucleotide polymorphisms (AISNPs) to discriminate East-Asian populations. In this study, we collected and examined the efficiency of 1185 AISNPs using frequency and genotype data from various publicly available databases. With the aim to perform fine-scale classification of S-Han, N-Han, Korean, and Japanese subjects, machine-learning methods (Softmax and Random Forest) were used to screen a panel of highly informative AISNPs and to develop a superior classification model. Stepwise classification was implemented to increase and balance the discrimination in the process of AISNP selection, first discriminating Han, Korean, and Japanese individuals, and then characterizing stratification between S-Han and N-Han. The final 272-AISNP panel is an alternative optimization of various previous works, which promises reliable and >90% accuracy in classification of the four East-Asian groups. This AISNP panel and the machine-learning model could be a useful and superior choice in medical genome-wide association studies and in forensic investigations for unknown suspect identity.     

Novel One-step Preparation of Functional Ionic Liquids Using Epoxides as Alkylation Reagents

Owing to their unique chemical and physical properties, ionic liquids (ILs) have received focus attention for application as solvent alternatives. ILs can be used in place of organic solvents in synthesis, catalysis, electrochem istry and liquid/liquid extractions. The commonly reported ILs have relied on pyridinium or imidazolium cations bearing simple alkyl groups.     

脉冲激光沉积制备非晶La0.75Sr0.25MnO3薄膜用于半透明阻变存储器

用脉冲激光沉积方法制备非晶La_0.75Sr_0.25MnO₃（a-LSMO）薄膜作为阻变器件（Ag/a-LSMO/ITO）的中间层,所得器件具有良好的非易失性和双极阻变行为。ITO衬底及超薄a-LSMO薄膜具有很高的可见光透过率,从而可制备半透明阻变器件。通过高分辨透射电镜直接观测到了在银电极与ITO电极间的银导电细丝。器件的阻变特性归因于在非晶镧锶锰氧层中的银导电细丝的生长与断裂。