全文获取类型
收费全文 | 1076篇 |
免费 | 73篇 |
国内免费 | 14篇 |
学科分类
医药卫生 | 1163篇 |
出版年
2024年 | 3篇 |
2023年 | 20篇 |
2022年 | 66篇 |
2021年 | 78篇 |
2020年 | 45篇 |
2019年 | 60篇 |
2018年 | 56篇 |
2017年 | 44篇 |
2016年 | 38篇 |
2015年 | 41篇 |
2014年 | 44篇 |
2013年 | 51篇 |
2012年 | 71篇 |
2011年 | 67篇 |
2010年 | 53篇 |
2009年 | 31篇 |
2008年 | 45篇 |
2007年 | 65篇 |
2006年 | 45篇 |
2005年 | 52篇 |
2004年 | 40篇 |
2003年 | 31篇 |
2002年 | 27篇 |
2001年 | 10篇 |
2000年 | 11篇 |
1999年 | 13篇 |
1998年 | 10篇 |
1997年 | 2篇 |
1996年 | 8篇 |
1995年 | 2篇 |
1994年 | 5篇 |
1993年 | 5篇 |
1992年 | 3篇 |
1991年 | 2篇 |
1990年 | 5篇 |
1989年 | 4篇 |
1988年 | 2篇 |
1987年 | 1篇 |
1984年 | 1篇 |
1983年 | 2篇 |
1978年 | 1篇 |
1977年 | 1篇 |
1974年 | 1篇 |
1969年 | 1篇 |
排序方式: 共有1163条查询结果,搜索用时 15 毫秒
21.
22.
Anemia and poor prognosis in advanced heart failure 总被引:1,自引:0,他引:1
Ghali JK 《Journal of the American College of Cardiology》2002,40(12):2204
23.
Jack L. Spurbeck Alan R. Zinsmeister Kevin J. Meyer Syed M. Jalal 《American journal of medical genetics. Part A》1996,61(4):387-393
Consistency of optimum chromosome spreading during harvest of cytogenetic specimens remains a major concern. We have tested the idea that a precise control of the drying rate (the time with which metaphase cells dry), as fixed cell suspension is placed on a slide or an in situ culture in last fixation, may be the answer. Amniocyte and lymphocyte cultures were allowed to dry at defined combinations of relative humidity (RH) and temperature (T) in a modified Thermotron environmental control unit. We were able to demonstrate, based on 2,250 amniocytes and 1,650 lymphocytes, that the metaphase area after drying was a function of RH and T for both in situ and non-in situ culture systems. As the RH and T increase, the metaphase area increases until a threshold is reached. Also, as RH increases, the slide drying time increases. Data obtained using a response surface regression, proportional hazards regression analysis and slide drying time studies are consistent with our model of chromosome spreading. Optimum metaphase areas can be achieved at various combinations of RH and T. We propose that the use of an environmental control unit is a practical way of achieving optimum chromosome spreading routinely and in a highly consistent manner. © 1996 Wiley-Liss, Inc. 相似文献
24.
Jalil Dolgari Sharaf Jalal Shayegh Peyman Mikaili 《Comparative clinical pathology》2012,21(1):117-118
Actinobacillus ureae, previously known as Pasteurella urea, is a commensal bacterium, which rarely causes disease in humans and has not been reported from any animal case in the veterinary literature. In this report, the occurrence of acute mastitis caused by A. ureae in an Iranian Ghezel sheep is described. 相似文献
25.
Fatemeh Beiraghdar Yunes Panahi Behzad Einollahi Eghlim Nemati Amirhossein Sahebkar Arash Hassanzadeh Hamid T. Khosroshahi Sima A. Azar Javid Safa Sadroddin R. Hashemi Jalal Etemadi Eisa T. Marzony Hamid Noshad 《Saudi Pharmaceutical Journal》2015,23(5):544-548
Background: The efficacy of human recombinant erythropoietins (rHuEPOs) in the treatment of anemia with different etiologies is proven. Development of biosimilar rHuEPO products with lower cost and wider availability is important for the care of anemic patients. Objective: The aim of the present study was to determine the bioequivalence and safety of a biosimilar rHuEPO (Pastopoitin®) and compare it with the innovator product Eprex®, as a standard rHuEPO. Methods: One hundred and seven anemic patients on stable hemodialysis were recruited to this randomized double-blind comparative trial and assigned to either subcutaneous Pastopoitin (n = 50) or Eprex (n = 57). Each study group received rHuEPO at a dose of 80–120 IU/kg/week in 2–3 divided doses for a period of 3 months. Hematologic parameters including Hemoglobin, hematocrit, RBC, EBC, platelet, MCV, MCH and MCHC were checked every 2 weeks. Blood iron, ferritin, TIBC, creatinine, BUN and electrolytes (Na, K, Ca and P) were evaluated monthly over the 3 months. Results: A significant increase in hemoglobin, hematocrit and RBC was observed by the end of study in both Pastopoitin and Eprex groups (p < 0.001). However, these factors were not significantly different between the groups, neither at baseline nor at the end of study (p > 0.05). Likewise, the groups were comparable regarding MCV, MCH, MCHC, iron, ferritin, TIBC, creatinine, BUN and electrolytes at baseline as well as at the end of trial. Adverse events were not serious and occurred with the same frequency in the study groups. Conclusion: Pastopoitin showed comparable efficacy and safety profile with Eprex in anemic patients on hemodialysis. Hence, Pastopoitin may be considered as a rHuEPO with a lower cost and wider availability compared with the innovator product Eprex. 相似文献
26.
Somayeh Shahani Mostafa Rostamnezhad Vahid Ghaffari-rad Arash Ghasemi Tayyeb Allahverdi Pourfallah Seyed Jalal Hosseinimehr 《Dose-response》2015,13(1)
The radioprotective effect of Achillea millefolium L (ACM) extract was investigated against genotoxicity induced by ionizing radiation (IR) in human lymphocytes. Peripheral blood samples were collected from human volunteers and incubated with the methanolic extract of ACM at different concentrations (10, 50, 100, and 200 μg/mL) for 2 hours. At each dose point, the whole blood was exposed in vitro to 2.5 Gy of X-ray and then the lymphocytes were cultured with mitogenic stimulation to determine the micronuclei in cytokinesis-blocked binucleated cell. Antioxidant capacity of the extract was determined using free radical-scavenging method. The treatment of lymphocytes with the extract showed a significant decrease in the incidence of micronuclei binucleated cells, as compared with similarly irradiated lymphocytes without any extract treatment. The maximum protection and decrease in frequency of micronuclei were observed at 200 μg/mL of ACM extract which completely protected genotoxicity induced by IR in human lymphocytes. Achillea millefolium extract exhibited concentration-dependent radical-scavenging activity on 1,1-diphenyl-2-picryl hydrazyl free radicals. These data suggest that the methanolic extract of ACM may play an important role in the protection of normal tissues against genetic damage induced by IR. 相似文献
27.
28.
Nadim El-Awar Anh Nguyen Khalid Almeshari Moheeb Alawami Fadi Alzayer Maha Alharbi Nori Sasaki Paul I. Terasaki 《Human immunology》2013
Donor-specific antibodies (DSA) in sera of sensitized transplant patients are often produced against the specific epitopes on mismatched HLA antigens. In this study, we selected sera from 30 kidney transplant patients with DSA and AMR to define DQ epitopes. Using adsorption and elution assays, we identified 18 antibody reaction patterns to define 6 new epitopes and to confirm 12 previously defined epitopes. In one patient case, one mismatched antigen produced 3 different antibodies and, in another, antibodies were produced against the alpha and beta chains of the same antigen. For some sera, a single epitope can explain reactions for 27 of the 29 DQ beads in the single antigen panel. 相似文献
29.
Devon E. Hinton Rebecca A. Ojserkis Baland Jalal Sonith Peou Stefan G. Hofmann 《Journal of clinical psychology》2013,69(8):817-828
This article discusses how loving‐kindness can be used to treat traumatized refugees and minority groups, focusing on examples from our treatment, culturally adapted cognitive‐behavioral therapy (CA‐CBT). To show how we integrate loving‐kindness with other mindfulness interventions and why loving‐kindness should be an effective therapeutic technique, we present a typology of mindfulness states and the Nodal Network Model (NNM) of Affect and Affect Regulation. We argue that mindfulness techniques such as loving‐kindness are therapeutic for refugees and minority populations because of their potential for increasing emotional flexibility, decreasing rumination, serving as emotional regulation techniques, and forming part of a new adaptive processing mode centered on psychological flexibility. We present a case to illustrate the clinical use of loving‐kindness within the context of CA‐CBT. 相似文献
30.
Farnia Vahid Bajoghli Hafez Golshani Senobar Shakeri Jalal Maurandi-López Antonio Rubio Luis Perez-Carceles Maria D. 《International journal of legal medicine》2021,135(4):1515-1524
International Journal of Legal Medicine - Elder abuse continues to be a taboo, mostly underestimated, ignored by societies across the world. Recent systematic reviews and meta-analyses have... 相似文献