无左心房和肺静脉三维重建的阵发性心房颤动导管消融术

Objective To investigate the differences between modeling and non-modeling left atrium in Carto XP system guided catheter ablation for paroxysmal atrial fibrillation. Methods Thirty-one cases of par-oxysmal atrial fibrillation treated by the same electrophysiologist with guidance of Carto XP during Jan to Dec in 2008 were enrolled. Catheter ablation was accomplished without left atrium and pulmonary veins modeling in 17 patients (non-modeling group) and with left atrium modeling in 14 patients (modeling group). The detailed ablation method was based on circumferential pulmonary veins isolation (CPVI). And linear ablation of tricus-pid valvular isthmus was selectively proceeded individually. The ablation endpoint was set to complete isolation of pulmonary vein potential from left atrium and no continuous fast atrial arrhythmia including atrial fibrillation, atrial flutter and atrial tachycardia could be induced. Comparisons for each step during procedure and the fol-low-up outcomes had been done. Results The male: female ratio of the 2 groups were 10:4 and 11 : 6 (P >0.05). The average age were (54.64 ± 15.58) and (59.41 ± 10.59) (P >0.05) ,the diseased courses were (5.05 ±10.4) years and (7.34±7.74)years(P >0.05),the left atrial sizes were (35.29±4.73) mm and (36.47 ±6.15)mm (P > 0.05), the total procedure time was (107.23±28.92) rain and (93.47 ±26.09) win (P>0.05). The X-ray exposure time was (21.09 ±6.49)min (modeling group) and (14.16±5.35)min (non-modeling group,P < 0.05). The CPVI time of fight pulmonary veins was (27.29±18.53) rain (model-ing group) and 18.00 ±4.51 min (non-modeling group, P < 0.05). The CPVI time of left pulmonary veins was (28.14 ±9.26) rain (modeling group) and (23.94±7.10) rain (non-modeling group, P < 0.05). The successful rates was 85.7% (modeling group) and 82.4% (non-modeling group, P > 0.05) over follow-up for 2 to 13 months. Conclusion Carto system guided catheter ablation of paroxysmal atrial fibrillation without modeling of left atrium and pulmonary veins could take less time in X-ray exposure and ablation steps, compa-ring with left atrium modeling one.     

肌电图对神经肌炎诊断探讨

神经肌炎的诊断是一个很困难而又有争论的问题,不管是从电生理学、组织学上来证实其诊断都有一定困难。因此Ludin提出“神经肌炎”是临床的概念。我院发现四例肌肉活检具有肌炎的改变,周围神经活检又具有节段性脱髓鞘改变。而肌电图检查也发现既有肌源性肌电图改变,又有周围神经病变的表现。为了探讨神经肌电图对神经肌炎是否有其诊断意义举一典型病例报导。杨××,住院号291160,男,48岁,病程10个月。发病前有咽部不适及吞咽困难,     

视觉诱发电位的数据处理与计算机辅助诊断的初步探讨

目前视觉诱发电位(Visual EvokedPotentials,VEP)的实验研究和临床诊断都只采用常规的时域分析方法。近几年来,应用计算机数据处理技术对诱发电位信号进行频域分析引起重视,但VEP频域分析的研究只有少量报道。Trick等对多发性硬化症患者的VEP作了功率谱分析,发现高频成分显著减少,时域和频域分析结合应用可使诊断率从61％提高到86％。Jutai等报道精神分裂症患者VEP的10-14Hz的频谱功率低于正常人。为了探讨VEP分析的新方法、临床诊断的新指标和提高诊断的正确率,我们从1986年6月开始,对VEP的数据处理与计算     

组织多普勒评价阵发性心房颤动患者环肺静脉左心房线性消融术后左心房功能变化

目的 利用组织多普勒超声评价阵发性心房颤动(房颤)患者环肺静脉左房线性消融术后左房功能的动态变化.方法 阵发性房颤患者108例,CARTO系统下行环肺静脉左房线性消融术,术前48 h及术后48 h、1个月、3个月、6个月分别行组织多普勒及常规超声心动图检查.结果 106例阵发性房颤患者成功施行环肺静脉左房线性消融术.与术前相比,左房前后径和左房容积减小,但术后48 h、1个月差异无统计学意义(P＞0.05),术后3个月和6个月差异有统计学意义(P＜0.05);左室舒张末内径、左室收缩末内径、左室射血分数差异无统计学意义(P＞0.05);二尖瓣舒张早期峰速差异无统计学意义(P＞0.05),二尖瓣舒张晚期峰速术后48 h较术前降低(P＜0.05),术后1个月、3个月、6个月逐渐增高,3个月时恢复到术前水平.与术前相比,二尖瓣环左室侧壁收缩期峰速、舒张早期峰速差异无统计学意义(P＞0.05),舒张晚期峰速术后48 h较术前降低(P＜0.05),术后1个月、3个月、6个月逐渐增高,1个月时恢复到术前水平.结论 环肺静脉左房线性消融术后左房内径和容积减小;环肺静脉左房线性消融术后可出现左房主动收缩功能降低(左房顿抑),经过一段时间可自行恢复.     

男孩体表“自燃”烧伤一例报告

人体“自燃”现象是人体特异现象的一种,临床上极为罕见,本院发现1例,报道如下。 患儿唐江,男,4岁半,因3小时内发生四次“自燃”烧伤入院。患儿母亲代诉,1990年4月15日上午,患儿坐在家里客厅沙发上,约8时孩子惊叫蹦跳起来,坐在他身旁的奶奶和客人见其会阴部冒烟燃烧,即脱下他的裤子,发现三条裤子都被烧烂有洞。至11时先后4次体表燃烧,其中1次有可见的蓝色“火球”.于当日下午5时入院,体检:发育正常、营养良好,心肺肝脾检查未见异常。烧伤情况:左前臂、左大腿有Ⅱ度烧伤3处,右大腿有Ⅲ度烧伤1处,会阴部及阴囊有Ⅱ～Ⅲ度烧伤,并有散在水疱6个(见封3图),右手食指和中指尖端烧有水疱,伤面均为圆形或椭圆形,表面高低不平,干燥无分泌物。心电图和脑电图检查均正常,血清钾、钠、镁、     

无左心房和肺静脉三维重建的阵发性心房颤动导管消融术

Objective To investigate the differences between modeling and non-modeling left atrium in Carto XP system guided catheter ablation for paroxysmal atrial fibrillation. Methods Thirty-one cases of par-oxysmal atrial fibrillation treated by the same electrophysiologist with guidance of Carto XP during Jan to Dec in 2008 were enrolled. Catheter ablation was accomplished without left atrium and pulmonary veins modeling in 17 patients (non-modeling group) and with left atrium modeling in 14 patients (modeling group). The detailed ablation method was based on circumferential pulmonary veins isolation (CPVI). And linear ablation of tricus-pid valvular isthmus was selectively proceeded individually. The ablation endpoint was set to complete isolation of pulmonary vein potential from left atrium and no continuous fast atrial arrhythmia including atrial fibrillation, atrial flutter and atrial tachycardia could be induced. Comparisons for each step during procedure and the fol-low-up outcomes had been done. Results The male: female ratio of the 2 groups were 10:4 and 11 : 6 (P >0.05). The average age were (54.64 ± 15.58) and (59.41 ± 10.59) (P >0.05) ,the diseased courses were (5.05 ±10.4) years and (7.34±7.74)years(P >0.05),the left atrial sizes were (35.29±4.73) mm and (36.47 ±6.15)mm (P > 0.05), the total procedure time was (107.23±28.92) rain and (93.47 ±26.09) win (P>0.05). The X-ray exposure time was (21.09 ±6.49)min (modeling group) and (14.16±5.35)min (non-modeling group,P < 0.05). The CPVI time of fight pulmonary veins was (27.29±18.53) rain (model-ing group) and 18.00 ±4.51 min (non-modeling group, P < 0.05). The CPVI time of left pulmonary veins was (28.14 ±9.26) rain (modeling group) and (23.94±7.10) rain (non-modeling group, P < 0.05). The successful rates was 85.7% (modeling group) and 82.4% (non-modeling group, P > 0.05) over follow-up for 2 to 13 months. Conclusion Carto system guided catheter ablation of paroxysmal atrial fibrillation without modeling of left atrium and pulmonary veins could take less time in X-ray exposure and ablation steps, compa-ring with left atrium modeling one.     

无左心房和肺静脉三维重建的阵发性心房颤动导管消融术

Objective To investigate the differences between modeling and non-modeling left atrium in Carto XP system guided catheter ablation for paroxysmal atrial fibrillation. Methods Thirty-one cases of par-oxysmal atrial fibrillation treated by the same electrophysiologist with guidance of Carto XP during Jan to Dec in 2008 were enrolled. Catheter ablation was accomplished without left atrium and pulmonary veins modeling in 17 patients (non-modeling group) and with left atrium modeling in 14 patients (modeling group). The detailed ablation method was based on circumferential pulmonary veins isolation (CPVI). And linear ablation of tricus-pid valvular isthmus was selectively proceeded individually. The ablation endpoint was set to complete isolation of pulmonary vein potential from left atrium and no continuous fast atrial arrhythmia including atrial fibrillation, atrial flutter and atrial tachycardia could be induced. Comparisons for each step during procedure and the fol-low-up outcomes had been done. Results The male: female ratio of the 2 groups were 10:4 and 11 : 6 (P >0.05). The average age were (54.64 ± 15.58) and (59.41 ± 10.59) (P >0.05) ,the diseased courses were (5.05 ±10.4) years and (7.34±7.74)years(P >0.05),the left atrial sizes were (35.29±4.73) mm and (36.47 ±6.15)mm (P > 0.05), the total procedure time was (107.23±28.92) rain and (93.47 ±26.09) win (P>0.05). The X-ray exposure time was (21.09 ±6.49)min (modeling group) and (14.16±5.35)min (non-modeling group,P < 0.05). The CPVI time of fight pulmonary veins was (27.29±18.53) rain (model-ing group) and 18.00 ±4.51 min (non-modeling group, P < 0.05). The CPVI time of left pulmonary veins was (28.14 ±9.26) rain (modeling group) and (23.94±7.10) rain (non-modeling group, P < 0.05). The successful rates was 85.7% (modeling group) and 82.4% (non-modeling group, P > 0.05) over follow-up for 2 to 13 months. Conclusion Carto system guided catheter ablation of paroxysmal atrial fibrillation without modeling of left atrium and pulmonary veins could take less time in X-ray exposure and ablation steps, compa-ring with left atrium modeling one.     

Lasso电极导管指导下标测与射频消融局灶性房性心动过速

目的 探讨10极Lasso电极导管对局灶性房性心动过速(房速)标测及射频消融的指导作用.方法 局灶性房速病人5例,接受电生理检查,初步判断房速起源于左心房或右心房;应用Lasso电极标测心房,指导消融导管寻找局灶性房速最早心房激动(A波)点,于最早心房激动点处消融.结果 局灶性房速病人5例均在房速持续发作时进行Lasso电极标测;消融导管在Lasso电极指导下分别于左心房耳部(2例)、左上肺静脉口部(1例)、上腔静脉(1例)、右心房侧壁(1例)标测到最早A波;较P波提早30～40 ms;Lasso电极记录的A波顺序均呈离心性;在上述最早激动点处消融,均成功终止房速,放电次数为1～3次;未出现并发症;随访2～20个月,无复发;手术时间40～60 min,X线照射时间8～12 min.结论 应用Lasso电极指导标测与射频消融局灶性房速,快速、准确,可提高消融成功率,减少X线照射时间,缩短手术时间,特别对病灶位于心内大静脉、心房耳部病例尤有帮助.     

眨眼反射

61:30,1980(英文)] 眨眼反射从1969年Bender等研究以来,已成为基础和应用生理学研究的重要课题。它是多突触还是少突触反射,基础神经生理学的许多研究已作探测,并对其脑干突触联系的许多部分还作了研究。最近,应用神经生理学的许多研究促进了眨眼反射通过大脑半球的探究,本文加以文献综述。最后,     

导管消融治疗45岁以下心房颤动患者的随访分析

目的研究不同类型的年轻心房颤动（房颤）患者（阵发性房颤、持续性房颤和持久的持续性房颤）导管消融治疗成功率和安全性。方法收集广东省心血管病研究所年龄〈45岁,诊断为房颤并接受导管消融治疗的132例患者的临床、电生理及随访资料,应用COX比例风险模型分析初次消融和重复消融后复发的预测因子。结果患者年龄（38.0±5.6）岁,男101例,女31例,既往房颤病程2.05年;阵发性房颤91例,非阵发性房颤包括持续性房颤15例和持久的持续性房颤26例。初次消融后随访24.2个月,阵发性、持续性、持久的持续性房颤成功率分别为86.8%（79例）、66.7%（10例）、57.7%（15例）,总体成功率78.8%。复发的患者有20例（71.4%）再次消融,随访14.3月,12例（75%）维持窦性心律。阵发性、持续性、持久的持续性房颤经过重复消融后窦性心律维持率分别为93.4%（85例）、86.7%（13例）、73.1%（19例）,总体成功率88.6%。COX回归分析提示,初次消融后复发的预测因子分别是非阵发性房颤（HR=3.393,P=0.004）、左心房扩大（HR=1.066,P=0.004）、高血压病史（HR=4.203,P=0.006）和甲状腺疾病史（HR=5.280,P=0.001）;重复消融后复发的预测因子则为右心房扩大（HR=1.133,P〈0.001）和甲状腺疾病（HR=6.942,P=0.003）。无影响预后的严重并发症。结论年轻的房颤患者导管消融安全性好,成功率高。早期对年轻房颤患者进行消融治疗是合理的,但应注意心房扩大及甲状腺疾病对成功率的影响。