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41.
Louis M. Rose Dimitrios S. Kolovos Richard F. Paige Fiona A. C. Polack Simon Poulding 《Software and Systems Modeling》2014,13(2):735-755
Model-driven engineering introduces additional challenges for controlling and managing software evolution. Today, tools exist for generating model editors and for managing models with transformation, validation, merging and weaving. There is limited support, however, for model migration—a development activity in which instance models are updated in response to metamodel evolution. In this paper, we propose conservative copy—a style of model transformation that we believe is well-suited to model migration—and Epsilon Flock—a compact model-to-model transformation language tailored for model migration. The proposed structures are evaluated by comparing the conciseness of model migration strategies written in different styles of transformation language, using several examples of evolution taken from UML and the graphical modelling framework. 相似文献
42.
Grafting of poly(acrylic acid) onto commercial polypropylene films following irradiation by γ-rays was carried out in order to improve their surface properties. The amount of grafting with the irradiation dose was found not to follow the expected linear dependence as it is normally observed for polypropylene films prepared in laboratory amounts. We therefore analyzed the influence of the industrial manufacture process in terms of orientation of the film and addition of antioxidants by determining the peroxide surface density and the extent of grafting therefrom. The unoriented polypropylene film presented the highest peroxide concentration and was thus the most adapated material for successful grafting. Whereas phenol antioxidants limit the peroxide formation and thus must be removed from the film for grafting, the thickness of the chemical modification and can be controlled by means of phosphites. Atomicforce microscopy and wettability measurements showed that the grafted poly(acrylic acid) was heterogeneously distributed on the surface of the film, explaining the observed low reproducibility of the grafting reaction. However, we observed that the polarity of the surface was increased by the grafting. © 1995 John Wiley & Sons, Inc. 相似文献
43.
A Sulzer SMX mixer was used to disperse gas into viscous, Newtonian and non-Newtonian fluids. The investigation covered the effect of the dispersed phase volume fraction, the viscosity of the continuous phase, the mixer length and the power draw. The flow regime was kept laminar in all the experiments. The dispersion of gas was carried out with gas concentrations between 1% and 7% in volume. Using the “process viscosity” concept, it was possible to collapse all the measured sizes on a single master curve by using the energy consumption in the mixer as the common variable between the experiments. Comparison was made with a Kenics mixer. The SMX mixer was found to be better adapted to the dispersion task due to its internal structure. 相似文献
44.
Apostolos Georgiou Louis Caston Christos Georgakis 《Chemical Engineering Communications》1987,60(1):119-144
The purpose of this paper is to investigate the dynamic properties of controller structures synthesized using extensive thermodynamic variables of a process. Several state-space and frequency domain multivariable techniques, including INA, and Modal Interaction Analysis, are used in order to evaluate the dynamic properties of these control structures. These structures show zero steady state interaction and minimal dynamic interaction for all processes examined. Dynamic simulation of several application examples, including distillation columns and a network of two stirred tank heaters in series, shows that the loops in these structures can also be tuned with minimum effort. Comparison of the proposed structures, with the conventional parallel single-input single-output control structures, shows the advantages of the proposed method. 相似文献
45.
Henry J. Pownall Joel D. Morrisett James T. Sparrow Louis C. Smith James Shepherd Richard L. Jackson Antonio M. Gotto Jr. 《Lipids》1979,14(4):428-434
The human plasma high density lipoproteins (HDL) are a heterogeneous ensemble of five proteins associated with both neutral
and polar lipids. The sequences of all five proteins are known. ApoA-I and apoA-II are the major protein components; apoC-I,
apoC-II and apoC-III are the minor protein components. All these apoproteins spontaneously recombine with phospholipids to
give stable lipid-protein complexes and freely exchange between the two major HDL subclasses, HDL2 and HDL3. In addition, ApoC-I, apoC-II, and apoC-III exchange between HDL and very low density lipoproteins. Furthermore, certain
HDL apoproteins are activators for plasma enzymes that are important in lipid metabolism. ApoA-I and apoC-I activate lecithin/cholesterol
acyltransferase; apoC-II is an activator of lipoprotein lipase. The regions of apoC-I and apoC-II that are involved in the
activation of these enzymes have been localized with synthetic peptides. Studies of synthetic and native fragments of apoA-II,
apoC-I, apoC-II, and apoC-III as well as model lipid-binding peptides have identified specific regions with structural features
common to lipid-binding proteins. These special properties, which include helical potential, sequences with a critical amphipathic
length, and high hydrophobicity of the nonpolar side of the amphipathic helix, are the determinants of HDL structure and metabolism. 相似文献
46.
Interaction between dietary protein and fat in triglyceride metabolism in the rat: Effects of soy protein and menhaden oil 总被引:4,自引:0,他引:4
The objective of the present study was to determine the mechanisms by which dietary proteins interact with dietary lipids
in the regulation of triglyceridemia in rats. Male Sprague-Dawley rats (n=56) were subjected to 28-d experimental diets containing different combinations of proteins (20% w/w) and lipid sources (14%
w/w): (i) casein-menhaden oil, (ii) casein-beef tallow, (iii) soy protein-menhaden oil, and (iv) soy protein-beef tallow.
Significant protein-lipid interactions were observed on triglyceridemia and hepatic cholesterol in fasted rats. The combination
of casein and beef tallow was associated with high plasma TG and hepatic cholesterol concentrations, which were reduced by
substitution either of soy for casein or of menhaden oil for beef tallow. Therefore, triglyceridemia and liver cholesterol
remained low with soy protein feeding, independently of the lipid source, as well as with menhaden oil feeding, regardless
of the protein source. The menhaden oil diets reduced plasma cholesterol, hepatic TG, and TG secretion compared with beef
tallow diets independently of the dietary protein source. Modifying the source of dietary proteins and lipids had no effect
on post-heparin plasma lipoprotein lipase activity. These results demonstrate that soy protein can lower rat triglyceridemia
relative to casein when associated with beef tallow consumption, whereas menhaden oil can attenuate hypertriglyceridemia when
rats are fed casein. The data further suggest that part of the hypotriglyceridemic effect of soy protein in the rat may be
mediated by reduced hepatic lipid synthesis, as is the case for menhaden oil. 相似文献
47.
为获得有抗氧化活性的工业用酵母菌株,对2株来源于原料乳中有较强抗氧化活性的酵母菌进行鉴定.根据菌株的表型、生理生化特征和基因型的特性,初步将这2株菌鉴定为毕赤氏发酵酵母(Pichia fermentans).将这2株酵母菌在高温灭菌(UHT)牛乳中培养以研究其对牛乳主要成分的影响,结果表明:这2株酵母能在UHT牛乳中产乙醇,具有促进蛋白水解活性与脂肪水解活性的能力,能有效提高乳中的游离氨基酸和脂肪酸的含量. 相似文献
48.
Most heterogeneous catalysts are either supported on some kind of porous material or the catalyst itself is porous. To satisfy practical constraints such as pressure drop, handling, and separation from products, these catalysts are generally pelletized. Very often the overall chemical reaction rates within these catalyst pellets are determined by a complicated interaction of internal and external transport effects with the intrinsic kinetic rate at the active surface. 相似文献
49.
Torsion and normal force measurements were made during single step stress relaxation experiments on a polymeric glass (PMMA). Isochronal data were analysed using an approach adapted from that developed by Penn and Kearsley1 (for incompressible elastic materials) to determine the derivatives , and of the time dependent strain potential function. and are determined from existing solution to the torsion of an incompressible cylinder. A special solution to the torsion of a compressible cylinder is presented and it is shown that the values of and obtained using this solution to analyse the data do not differ greatly from those obtained using the incompressible solution. It is found from both solutions that is negative and increases towards zero with increasing time and deformation while is positive, greater in magnitude than and decreases towards zero with increasing time and deformation. These results were unexpected and a full understanding of their meaning has yet to be reached. 相似文献
50.
Effect of Microstructure on the Tribological and Mechanical Properties of CuO-Doped 3Y-TZP Ceramics 总被引:1,自引:0,他引:1
Shen Ran Louis Winnubst Dave H. A. Blank Henry R. Pasaribu Jan-Willem Sloetjes Dik J. Schipper 《Journal of the American Ceramic Society》2007,90(9):2747-2752
Dense 8 mol% CuO-doped 3Y-TZP ceramics were prepared by pressureless sintering for 8 h at 1500° and 1550°C, respectively. Transmission electron spectroscopy revealed that the ceramic sintered at 1500°C exhibits grain boundaries free of any amorphous phase, while crystalline copper-oxide grains were found in the zirconia matrix, whereas the sample sintered at 1550°C contains a Cu-rich amorphous grain boundary layer. The tribological behavior of these materials was tested under dry-sliding conditions using a pin-on-disk tribometer. The material sintered at 1500°C showed self-lubrication resulting in a low coefficient of friction ( f ) of 0.2–0.3 and a low specific wear rate ( k ) ≪ 10−6 mm3 ·(N·m)−1 . In contrast, the material sintered at 1550°C showed poor tribological behavior ( f =0.8–0.9; k ≫ 10−6 mm3 ·(N·m)−1 under the same conditions. The difference in the tribological behavior of these two materials was interpreted on the basis of mechanical properties and microstructural characteristics. 相似文献