Isothermal interphase diffusion with consecutive reactions

For multi-step heterogeneous consecutive reactions affected entirely by interphase diffusion under isothermal condition, the equations for the effectiveness factors, the surface concentrations and the point yields were derived in terms of the Damkoehler numbers or the measurables from the mass balances set up on the assumption that the mass-transfer rate balances the surface-reaction rate at steady state. From the analyses of the equations derived, the effectiveness factors for the intermediate steps and the surface concentrations of intermediates were understood to be enhanced by the measurables inclusive of the concentrations and the mass-transfer coefficients. Then the effect of the concentrations was concluded to be most significant. The effects of these measurables to the effectiveness factors and the surface concentrations were qualitatively discussed for simple consecutive reactions and also for additive consecutive reactions. Especially, as for two-step additive consecutive reactions, the effects of measurables η Da and the concentrations to the effectiveness factors were examined with graphical presentations. Finally, the brief discussion of the dependency of the Damkoehler number upon reaction time and the effect of the Renolds number and diffusivity to the extent of the mass-transfer resistance were presented.     

Transparent ultra-long-haul DWDM networks with "broadcast-and-select" OADM/OXC architecture

We describe an experimental realization of ultra-long-haul (ULH) networks with dynamically reconfigurable transparent optical add-drop multiplexers (OADMs) and optical cross-connects (OXCs). A simple new approach to dispersion management in ULH dense-wavelength-division-multiplexing (DWDM) transparent optical networks is proposed and implemented, which enables excellent transmission performance while avoiding dispersion compensation on a connection-by-connection basis. We demonstrate "broadcast-and-select" node architectures that take full advantage of this method. Our implementation of signal leveling ensures minimum variations of path-averaged power among the wavelength-division-multiplexing (WDM) channels between the dynamic gain-equalizing nodes and results in uniform nonlinear and spontaneous-emission penalties across the WDM spectrum. We achieve 80/spl times/10.7-Gb/s DWDM networking over 4160 km (52 spans/spl times/80 km each) of all-Raman-amplified symmetric dispersion-managed fiber and 13 concatenated OADMs or 320/spl times/320 wavelength-port OXCs with 320-km node spacing. The WDM channels use 50-GHz grid in C band and the simple nonreturn-to-zero (NRZ) modulation format. The measured Q values exhibit more than a 1.8-dB margin over the forward-error correction threshold for 10/sup -15/ bit-error-rate operation. We compare these results with point-to-point transmission of 80/spl times/10-Gb/s NRZ WDM signals over 4160 km without OADM/OXC and provide detailed characterization of penalties due to optical signal-to-noise-ratio degradation, filter concatenation, and crosstalk.     

New queueing strategies employing service interval-based priority for real-time communications in atm networks

In this paper, we propose queueing strategies employing the service interval-based priority (sip) which can provide delay-bounded, and loss-free services, while maximizing bandwidth utilization in the atm network. We also describe a variation of the sip, the residual service interval-based priority (rsip) which can achieve almost full utilization by assigning priorities dynamically on the basis of the residual service interval. We store the realtime cells belonging to different connections in logically separated queues, and for each queue, we set a parameter called service interval, during which only one cell is allowed to be transmitted. The sip server takes and transmits the head-of-line (hol) cell of the queue which has the smallest service interval, while the rsip server selects the queue with the smallest residual service interval. When there is no eligible real-time cell, it transmits non-real-time cell, thus enabling a maximized bandwidth utilization. Employing the above queueing strategies, we analyze the delay characteristics deterministically with the leaky bucket bounded input traffic and then dimension the optimal service interval. In dimensioning the service interval and buffer space of each real-time service queue, we consider burstiness of traffic in conjunction with delay constraints, so that bandwidth utilization can get maximized. In addition, we consider the issues of protection from malicious users, average bandwidth utilization, and coupling between the delay bound and the bandwidth allocation granularity.     

Analysis of culture fluorescence by a fiber-optic sensor inNicotiana tabacum plant cell culture

The on-line sensing of viable cell weight in plant cell culture process is applied to analysis and control of process. The fiber-optic fluorescence sensor was constructed to measure the NADH-dependent fluorescence inNicotiana tabacum plant cell culture and the analysis of fluorescence signal was done to be correlated with the viable cell weight. The structured kinetic model for cell growth was proposed to estimate the theoretical viable cell weight. The dimensional analysis was proposed for the interpretation of fluorescence signal, in which the path length, the inner filter effect and the hydrodynamic conditions were considered as the key factors on fluorescence signal. The dimensional analysis and empirical correlation of fluorescence signal to viable cell weight was applied to the interpretation of the detected fluorescence signal during cultivation. The proposed interpretation of fluorescence signal using dimensional analysis was well correlated with the viable cell weight estimated by the structured kinetic model as well as by empirical correlation.     

Extraction of penicillin G from simulated media by an emulsion liquid membrane process

The extraction of penicillin G from simulated media was performed by water/oil/water (w/o/w) emulsion liquid membranes (ELMs) and studied under various operational conditions in a batch system. The degree of extraction achieved was between 80% and 95% under specific conditions. A concentration of greater than nine times the initial concentration of penicillin G in the external phase was obtained in the internal phase. The pH of the internal aqueous solution, containing a basic salt, was theoretically calculated on the basis of the amount of penicillin G transported into the internal phase. The calculated results agreed with the experimental data well and were used to select a suitable type and concentration of a basic salt in the internal phase to give a pH within the range 5 to 8 where penicillin G was stable after the termination of extraction. The extraction of penicillin G was successfully performed by the ELM process with sodium carbonate in the internal phase.     

Application of artificial neural networks to the analysis of two‐dimensional fluorescence spectra in recombinant E coli fermentation processes

A two‐dimensional (2D) spectrofluorometer was used to monitor various fermentation processes with recombinant E coli for the production of 5‐aminolevulinic acid (ALA). The whole fluorescence spectral data obtained during a process were analyzed using artificial neural networks, ie self‐organizing map (SOM) and feedforward backpropagation neural network (BPNN). The SOM‐based classification of the whole spectral data has made it possible to qualitatively associate some process parameters with the normalized weights and variances, and to select some useful combinations of excitation and emission wavelengths. Based on the classified fluorescence spectra a supervised BPNN algorithm was used to predict some of the process parameters. It was also shown that the BPNN models could elucidate some sections of the process's performance, eg forecasting the process's performance. Copyright © 2005 Society of Chemical Industry     

Microstructural investigation of long-term degradation mechanisms in GFRP dowel bars for jointed concrete pavement

Steel dowel bar is used to transfer loads in concrete pavement slab. However, once the steel dowel bar corrodes, it may cause faults, such as joint freezing in concrete pavement, level differences resulting from spalling or decreased efficiency of load transfer, etc., which are the same problems experienced by typical reinforcing steel. This study evaluated the applicability of glass fiber-reinforced polymer (GFRP) dowel bar as a substitute for steel dowel bar. A microstructural analysis was conducted to examine the decrease in durability of GFRP dowel bar exposed to deterioration environments. To analyze the deterioration mechanism of GFRP dowel bar, scanning electron microscopy was employed and the porosity was measured by the gas absorption method. It was concluded that the longer the GFRP dowel bar was exposed to deterioration environments, the more the interlaminar shear stress decreased. This result was validated by the microstructural analysis. © 2008 Wiley Periodicals, Inc. J Appl Polym Sci, 2008     

Preparation of monodisperse poly(vinyl alcohol) microspheres by heterogeneous surface saponification and iodine complex formation

Monodisperse poly(vinyl acetate) (PVAc) microspheres with high molecular weight obtained by suspension polymerization of vinyl acetate were saponified in alkaline aqueous solution to keep their spherical structure. The saponification was restricted on the surface of the PVAc microspheres and obtained particles had skin/core structure. Various poly(vinyl alcohol) (PVA) microspheres with different diameters and degrees of saponification (DSs) were obtained. The conversion of PVAc to PVA during the heterogeneous surface saponification time were examined by nuclear magnetic resonance spectroscopy and after 72 h hydrogel type PVA microspheres completely saponified were obtained. The crystal melting temperatures of the microspheres obtained by the saponification were measured a constant value of 238°C irrespective of varying DS, and the peaks became enlarged as reaction time. Iodine complexes were formed in saponified microspheres with DS of 41% and 99% by immersing them in I₂/KI aqueous solution and decomposed by the reduction of I₂ in the complexes to 2I^? using sodium sulfite to confirm whether the skin formed through the saponification was composed of PVA with high VA content. Obviously, characteristic blue color developments owing to I₅^?‐PVA complexes were observed in both saponified regions and a red in the PVAc core. Consequently, it was concluded that the PVA skins formed by heterogeneous surface saponification had high DSs. Such complexes endowed polymeric microspheres a good radiopacity which would be useful in clinical treatment of vascular diseases and were examined by X‐ray irradiation image. © 2007 Wiley Periodicals, Inc. J Appl Polym Sci, 2008