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81.
Eiichi Wakai Michiyoshi Yamamto Joaquin Molla Takehiko Yokomine Shunhei Nogami 《Fusion Engineering and Design》2011,86(6-8):712-715
The main purpose of present phase of IFMIF/EVEDA (International Fusion Materials Irradiation Facility/Engineering Validation and Engineering Design Activities) is to produce a detailed report of IFMIF engineering design with the integrated design of all facilities in IFMIF. The main function of the IFMIF is to give the demanded design database for the licensing of DEMO reactors and further reactors, and it is achieved from the materials data set obtained from the high, medium, and low flux test modules (HFTM, MFTM and LFTM) of IFMIF. In the evaluation using small specimens, developments and guidelines of small specimen test technique or technology (SSTT) are also demanded for the achievements. This paper is summarized and also analyzed about the design plan status and requirements in these test modules from users, and testing items and test methodology in IFMIF. 相似文献
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López V Ortiz S Corujo A López P Navas J Moreno R Martínez-Suárez JV 《Journal of food protection》2007,70(6):1513-1517
In surveys conducted on finished product samples from a single poultry processing plant in Spain, Listeria monocytogenes was found in 14 different uncooked products. To track contamination patterns, 77 L. monocytogenes isolates were characterized by PCR-based serotyping, pulsed-field gel electrophoresis (PFGE) restriction analysis, and PCR-based allelic analysis of the virulence gene actA. Serotyping revealed that 12 isolates (15.6%) were of the L. monocytogenes serotype 4b complex (serotype 4b or the closely related serotypes 4d and 4e). A combination of endonucleases AscI and ApaI PFGE patterns yielded 15 different pulsotypes among all 77 tested isolates. All the serotype 4b isolates belonged to one pulsotype. Sequencing of the actA gene confirmed that all serotype 4b isolates corresponded to the same allelic subtype. The subtype was recovered from five product types, but its presence was not correlated with the production line or the date of isolation, suggesting a possible association of this strain with a common ingredient. This traceback investigation established that pork dewlap, an ingredient common to all the products contaminated with this strain, was the most probable source of L. monocytogenes 4b. The same 4b strain was isolated from four samples of pork dewlap from one specific supplier. After replacement of this contaminated ingredient in the fresh products, this strain of L. monocytogenes serotype 4b was not detected. This study confirms the effectiveness of molecular subtyping to control contamination by specific strains of L. monocytogenes and the importance of testing the different ingredients added to the food products. 相似文献
84.
Laura De Marzi Antonina Monaco Joaquin De Lapuente David Ramos Miquel Borras Mario Di Gioacchino Sandro Santucci Anna Poma 《International journal of molecular sciences》2013,14(2):3065-3077
Owing to their radical scavenging and UV-filtering properties, ceria nanoparticles (CeO2-NPs) are currently used for various applications, including as catalysts in diesel particulate filters. Because of their ability to filter UV light, CeO2-NPs have garnered significant interest in the medical field and, consequently, are poised for use in various applications. The aim of this work was to investigate the effects of short-term (24 h) and long-term (10 days) CeO2-NP exposure to A549, CaCo2 and HepG2 cell lines. Cytotoxicity assays tested CeO2-NPs over a concentration range of 0.5 μg/mL to 5000 μg/mL, whereas genotoxicity assays tested CeO2-NPs over a concentration range of 0.5 μg/mL to 5000 μg/mL. In vitro assays showed almost no short-term exposure toxicity on any of the tested cell lines. Conversely, long-term CeO2-NP exposure proved toxic for all tested cell lines. NP genotoxicity was detectable even at 24-h exposure. HepG2 was the most sensitive cell line overall; however, the A549 line was most sensitive to the lowest concentration tested. Moreover, the results confirmed the ceria nanoparticles’ capacity to protect cells when they are exposed to well-known oxidants such as H2O2. A Comet assay was performed in the presence of both H2O2 and CeO2-NPs. When hydrogen peroxide was maintained at 25 μM, NPs at 0.5 μg/mL, 50 μg/mL, and 500 μg/mL protected the cells from oxidative damage. Thus, the NPs prevented H2O2-induced genotoxic damage. 相似文献
85.
Pablo Ardura ;Gonzalo Alonso ;Jose Manuel Cano ;Joaquin Gonzalez Nomiella ;Francisco Pedrayes ;Femando Briz ;Manes Fernandez Cabanas ;Manuel Garcia Melero ;Carlos Hiram Rojas ;Jose Ramon Gonzadez Suaxez 《能源与动力工程:英文版》2014,(9):1633-1641
This paper presents an analysis of the electric power flows in a hot rolling mill plant using a power quality analyzer and developing simulation models with Matlab-Simulink. The model inputs have been taken from process data by the process computer of the plant. Data from different rolling campaigns have been analysed. A STATCOM (static synchronous compensator) with a control strategy based on voltage oriented control with d-q coordinates is used as solution to improve the reactive compensation as well as to minimize the voltage fluctuations and sags effect. The overall electric model has been simulated with the STATCOM to check the improvement in the voltage stability and the consumption. 相似文献
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88.
Joaquin Vanschoren Hendrik Blockeel Bernhard Pfahringer Geoffrey Holmes 《Machine Learning》2012,87(2):127-158
Thousands of machine learning research papers contain extensive experimental comparisons. However, the details of those experiments
are often lost after publication, making it impossible to reuse these experiments in further research, or reproduce them to
verify the claims made. In this paper, we present a collaboration framework designed to easily share machine learning experiments
with the community, and automatically organize them in public databases. This enables immediate reuse of experiments for subsequent,
possibly much broader investigation and offers faster and more thorough analysis based on a large set of varied results. We
describe how we designed such an experiment database, currently holding over 650,000 classification experiments, and demonstrate
its use by answering a wide range of interesting research questions and by verifying a number of recent studies. 相似文献
89.
Isabelle E. François Dr. Karin Thevissen Dr. Klaartje Pellens Dr. Els M. Meert Jan Heeres Dr. Eddy Freyne Dr. Erwin Coesemans Dr. Marcel Viellevoye Dr. Frederik Deroose Dr. Sonia Martinez Gonzalez Dr. Joaquin Pastor Dr. David Corens Dr. Lieven Meerpoel Dr. Marcel Borgers Dr. Jannie Ausma Dr. Gerrit D. Dispersyn Dr. Bruno P. Cammue Prof. Dr. 《ChemMedChem》2009,4(10):1714-1721
In this study, we screened a library of 500 compounds for fungicidal activity via induction of endogenous reactive oxygen species (ROS) accumulation. Structure–activity relationship studies showed that piperazine‐1‐carboxamidine analogues with large atoms or large side chains substituted on the phenyl group at the R3 and R5 positions are characterized by a high ROS accumulation capacity in Candida albicans and a high fungicidal activity. Moreover, we could link the fungicidal mode of action of the piperazine‐1‐carboxamidine derivatives to the accumulation of endogenous ROS. 相似文献
90.
Fernando Alonso-Fernandez Julian Fierrez-Aguilar Hartwig Fronthaler Klaus Kollreider Javier Ortega-Garcia Joaquin Gonzalez-Rodriguez Josef Bigun 《电信纪事》2007,62(1-2):62-82
We report on experiments for the fingerprint modality conducted during the First BioSecure Residential Workshop. Two reference systems for fingerprint verification have been tested together with two additional non-reference systems. These systems follow different approaches of fingerprint processing and are discussed in detail. Fusion experiments I volving different combinations of the available systems are presented. The experimental results show that the best recognition strategy involves both minutiae-based and correlation-based measurements. Regarding the fusion experiments, the best relative improvement is obtained when fusing systems that are based on heterogeneous strategies for feature extraction and/or matching. The best combinations of two/three/four systems always include the best individual systems whereas the best verification performance is obtained when combining all the available systems. 相似文献