Nup154, a new Drosophila gene essential for male and female gametogenesis is related to the nup155 vertebrate nucleoporin gene

The Nup154 gene of Drosophila encodes a protein showing similarity with known nucleoporins: rat Nup155 and yeast Nup170 and Nup157. Hypomorphic mutant alleles of Nup154 affected female and male fertility, allowing investigation of the gene function in various steps of oogenesis and spermatogenesis. Nup154 was required in testes for cyst formation, control of spermatocyte proliferation and meiotic progression. In ovaries, Nup154 was essential for egg chamber development and oocyte growth. In both the male and female germ line, as well as in several other cell types, the Nup154 protein was detected at the nuclear membrane, but was also present inside the nucleus. Intranuclear localization has not previously been described for rat Nup155 or yeast Nup170 and Nup157. In mutant egg chambers the Nup154 protein accumulated in the cytoplasm, while it was only barely detected at the nuclear envelopes. FG repeats containing nucleoporins detected with mAb414 antibody were also mislocalized to a certain extent in Nup154 mutant alleles. This suggests that Nup154 could be required for localizing other nucleoporins within the nuclear pore complex, as previously demonstrated for the yeast Nup170. On the other hand, no evident defects in lamin localization were observed, indicating that Nup155 mutations did not affect the overall integrity of the nuclear envelope. However, ultrastructural analyses revealed that in mutant cells the morphology of the nuclear envelope was altered near the nuclear pore complexes. Finally, the multiplicity of phenotypes observed in Nup154 mutant alleles suggests that this gene plays a crucial role in cell physiology.     

Structural and magnetic resonance properties of permalloy films epitaxially grown on f.c.c. metals

Single-crystal permalloy films have been prepared by epitaxy on different f.c.c. metals epitaxied on mica. Various methods of preparation of the f.c.c. metals have been tested: epitaxy of gold on mica at 400°C; epitaxy of silver on mica at 300°C; epitaxy of copper on mica at 500°C; and recrystallization of a thin silver film on mica.     

MMPI characteristics of college freshman males who later became alcoholics.

Compared the MMPI scores of 32 college freshman males later hospitalized as alcoholics with scores of 148 control male classmates for clinical, content scale, and item differences. The prealcoholics were significantly higher on the Psychopathic Deviate, Hypomania and F scales. It is concluded that the college prealcoholic is more likely to be impulsive, nonconforming, and gregarious but is otherwise not grossly maladjusted compared to his peers. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Development of rate expressions for the catalytic decomposition of nitric oxide with ammonia on iron oxide

The reduction of nitric oxide with ammonia on iron oxide catalysts has been studied in a continuous-flow recycle reactor using simulated flue gas in the temperature range from 573 to 673 K. NO and HN₃ concentrations were varied between 0 and 1000 vpm, O₂ and H₂O concentrations between 0 and 9 vol.-%, the remainder being nitrogen. In the presence of oxygen, the formulated reaction rate equation describes the measured rates of the main reaction NO + 2/3 NH₃ ? 5/6 N₂ + H₂O. Its form corresponds to the Langmuir-Hinshelwood type. The rate equation well fits the data, which cover the whole industrial temperature and concentration range. In the absence of oxygen, the measured reaction rates can be best described by a power law.     

The Cognitive Origins of Social Stratification

In evolutionary psychology, cultural phenomena are explained with reference to evolved psychological processes. This paper presents an economic approach to explore this link by demonstrating how social stratification can arise in game-playing populations as a result of social categorisation of and inference from arbitrary agent traits. The computer simulation of the model demonstrates that agents' increasing ability to categorise opponents in the chicken game generates an increasing number of social groups whose members share commonality of fate both in terms of opponent behaviour and payoff levels. JEL classification: C72, D83, J70     

The structure of enumerated spin glass state spaces

We enumerate the low energy part of the state space of an Ising spin glass using an efficient branch-and-bound algorithm. A coarse graining algorithm (NB-clustering) is employed to condense the inherent information to a system size which is treatable in computer simulations. The reduced state space still incorporates all ingredients necessary to simulate aging effects. We investigate its structure in detail and find that certain assumptions made in heuristical state space models which have been presented in the past to reproduce aging phenomena in spin glass experiments are indeed compatible with the data from the observed state spaces.     

Ethik in der Medizin—Schlaglichter aus der Sichtprotestantischer Ethik

Ohne Zusammenfassung     

Reduced density of effective electrons in metal films

The thickness-dependent conductivity 〈σ(d?)〉 of aluminium, gold and copper films was measured during evaporation by a process-controlled experiment. From the digitally recorded data four parameters (σ_∞, l_∞, p, h) were evaluated by applying an extended Fuchs' theory. The conductivity σ_∞ due to volume scattering of the electrons depends on the evaporation conditions and is always less than σ_bulk for single-crystal bulk material. The decrease in σ_∞ compared with σ_bulk is found to be caused by localization of charge carriers rather than by a decrease in the mean free path.     

Entwicklung mit Hilfe des Warmpreßverfahrens hergestellter Sinterstähle mit optimaler Warmstreckgrenze,Dauerfestigkeit und Kerbschlagzähigkeit – Teil 1

Development of Hot-Forged Sintered Steels with Optimum Yield Point at Higher Temperature, Fatigue and Impact Strength . The material characteristic values of hot-forged sintered steels are reported. Besides the usual properties, (ultimate tensile strength, yield strength and elongation at room temperature). The behaviour of materials at higher temperature is of great importance. Further, fatigue strength and impact strength must be considered. The influence of heat treatment on these properties were investigated and brought to a correlation with the formation of microstructures. The hot forging P/M preform requires a special attention on alloying elements and alloying techniques. Optimum properties results when using completely alloyed powders or mixed powders by employing special master alloys. This and further problems involving alloying techniques and particularly the behaviour of carbon as an alloying element is reported in details. The correlation between mechanical properties and fracture behaviour is discussed.