全文获取类型
收费全文 | 11871篇 |
免费 | 785篇 |
国内免费 | 23篇 |
学科分类
医药卫生 | 12679篇 |
出版年
2023年 | 55篇 |
2022年 | 57篇 |
2021年 | 245篇 |
2020年 | 163篇 |
2019年 | 271篇 |
2018年 | 309篇 |
2017年 | 209篇 |
2016年 | 253篇 |
2015年 | 240篇 |
2014年 | 427篇 |
2013年 | 586篇 |
2012年 | 902篇 |
2011年 | 952篇 |
2010年 | 528篇 |
2009年 | 487篇 |
2008年 | 832篇 |
2007年 | 799篇 |
2006年 | 782篇 |
2005年 | 826篇 |
2004年 | 752篇 |
2003年 | 716篇 |
2002年 | 651篇 |
2001年 | 103篇 |
2000年 | 69篇 |
1999年 | 91篇 |
1998年 | 140篇 |
1997年 | 104篇 |
1996年 | 105篇 |
1995年 | 92篇 |
1994年 | 73篇 |
1993年 | 56篇 |
1992年 | 63篇 |
1991年 | 50篇 |
1990年 | 39篇 |
1989年 | 42篇 |
1988年 | 64篇 |
1987年 | 46篇 |
1986年 | 41篇 |
1985年 | 32篇 |
1984年 | 48篇 |
1983年 | 47篇 |
1982年 | 48篇 |
1981年 | 34篇 |
1980年 | 48篇 |
1979年 | 28篇 |
1978年 | 21篇 |
1977年 | 21篇 |
1976年 | 20篇 |
1974年 | 16篇 |
1972年 | 15篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
61.
The authors prospectively studied consecutive neurological inpatients with either motor conversion symptoms or pseudoseizures of recent onset. Patients were administered a structured psychiatric diagnostic interview, a measure of perceived parental care, and a life events inventory. They found that patients with pseudoseizures (N=20, mean age=27 years): 1) were younger than patients with motor conversion symptoms (N=30, mean age=39 years), 2) were more likely to have a borderline personality disorder), 3) were more likely to have a lower perception of parental care and to report incest, and 4) reported more life events in the 12 months before symptom onset. These differences in their characteristics and associated factors raised the question of whether it is helpful to group patients with pseudoseizures and motor conversion symptoms in a single diagnostic category of conversion disorder. An alternative view, that gives primacy to the symptoms rather than a disorder, may enable more precise research questions to be posed. 相似文献
62.
End-of-life (EOL) and palliative care education in medical school curricula stand at a crossroads. Consensus has emerged that these topics merit systematic instruction throughout medical school training, yet curricula all too often consist of sporadic lectures focused on bioethics instead of clinical skills. The medical student authors identified a deficit in their curriculum, and designed and implemented an EOL curriculum module for their colleagues. In early 2000 the authors surveyed senior medical students about their experiences with EOL and palliative education, identifying deficits in clinical training and recommendations for interventions. They then designed a case-based educational module to teach EOL communication skills to medical students commencing clinical training. Faculty with national and local experience with EOL and palliative care reviewed the curriculum. Twelve of these faculty were oriented to the curriculum and then taught it in pairs to groups of 12 to 16 medical students in 2000 and 2001. The curriculum develops skills, attitudes, and knowledge relevant for communicating bad news and establishing treatment options in the EOL setting by utilizing trigger videos, group discussion, role plays, and case discussions. Approximately 75% of the 86 eligible students attended the module in 2000 and 2001. Feedback has guided the curriculum's refinement by the medical student authors. In addition, a standardized patient exercise, introduced in 2001, allowed students to reinforce the skills learned during the module. 相似文献
63.
64.
Assessment of the epidemic potential of a new strain of rotavirus associated with the novel G9 serotype which caused an outbreak in the United States for the first time in the 1995-1996 season
下载免费PDF全文
![点击此处可从《Journal of clinical microbiology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Clark HF Lawley DA Schaffer A Patacsil JM Marcello AE Glass RI Jain V Gentsch J 《Journal of clinical microbiology》2004,42(4):1434-1438
Rotavirus causes severe morbidity in developed countries and frequent deaths (> or = 500,000 per year) in less-developed countries. Historically, four serotypes--G1, G2, G3, and G4-have predominated; they are distinguished by one of two surface neutralization antigens (VP7). However, in 1983 and 1984 we described a new rotavirus serotype, designated G9, in five children hospitalized for diarrhea in Philadelphia, Pa. G9 rotavirus was not identified again in the Western Hemisphere until it caused ca. 50% of the rotavirus disease detected in Philadelphia in the 1995-1996 season. This outbreak allowed us to question whether a rotavirus strain completely new to a well-studied community would target either very young infants or older children, cause especially severe disease, or completely displace previously extant serotypes. We observed a significant excess of G9 infections in younger infants (especially in those < 6 months old) that might be attributed to the lack of G9-specific antibodies in mothers. Of further note, six of the seven oldest patients with rotavirus diarrhea were infected with the G9 strains (not significant). However, the age distribution of children with rotavirus did not differ over a 5-year study period regardless of the infecting serotype. Patients with diarrhea associated with G9 strains did not have disease more severe than that caused by the G1, G2, or G3 serotype. G9 strains did not displace the other serotypes but were virtually completely replaced by G1 or G2 serotypes in the three subsequent rotavirus seasons. We conclude that the abrupt appearance of this novel rotavirus serotype did not present a special threat to public health in the community. 相似文献
65.
66.
67.
Description of the transcriptomes of immune response-activated hemocytes from the mosquito vectors Aedes aegypti and Armigeres subalbatus 总被引:3,自引:0,他引:3
下载免费PDF全文
![点击此处可从《Infection and immunity》网站下载免费的PDF全文](/ch/ext_images/free.gif)
68.
Michelle K Williamson Jane Pirkis Jon J Pfaff Orla Tyson Moira Sim Ngaire Kerse Nicola T Lautenschlager Nigel P Stocks Osvaldo P Almeida 《BMC medical research methodology》2007,7(1):42
Background
Recruiting and retaining GPs for research can prove difficult, and may result in sub-optimal patient participation where GPs are required to recruit patients. Low participation rates may affect the validity of research. 相似文献69.
Vonen Barthold Bertheussen Kjell Giæver Anton K. Florholmen Jon Burhol Per G. 《Methods in Cell Science》1992,14(2):45-50
Summary Serum contains insulin degrading components. We have evaluated the insulin and somatostatin secretion from isolated rat pancreatic islets during a 2-wk culture period using three different serum-containing media, and one serum-free medium with a synthetic serum replacement. Islets incubated in serum-free medium elicited significantly higher daily insulin and somatostatin secretions than islets incubated in the serum-containing media. After a 2-wk culture period, islets from the serum-free medium secreted significantly more insulin and somatostatin than islets cultured in other media when stimulated with 25 mmol/liter glucose together with 15 mmol/liter theophylline. We conclude that the serum-free medium is superior for long-term culture of rat pancreatic islets. 相似文献
70.