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目的观察草酸艾司西酞普兰联合左甲状腺素钠治疗亚临床甲状腺功能减退伴焦虑抑郁的效果。方法选取 2015年 1月至 2018年 7月东海县人民医院亚临床甲状腺功能减退伴焦虑抑郁病人 90例,采用随机数字表法分为西酞普兰组、左甲状腺素钠组和联合组,每组 30例。分别予以草酸艾司西酞普兰、左甲状腺素钠和草酸艾司西酞普兰 +左甲状腺素钠联合治疗。 8周后,观察三组治疗前后游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)、促甲状腺激素(TSH)水平和汉密尔顿焦虑量表(HAMA)及汉密尔顿抑郁量表(HAMD)评分的变化。结果治疗后与治疗前相比,西酞普兰组 TSH[(7.70±1.09)μIU/mL比(7.77±1.03)μIU/mL]、 FT3[(4.28±0.73)pmol/L比(4.30±0.58)pmol/L]、 FT4[(9.72±1.03)pmol/L比(9.98±1.09)pmol/L]无变化(P>0.05)TSH左甲状腺素钠组[(4.39±0.76)μIU/mL比(7.69±1.01)μIU/mL]和联合组[(4.30±0.51)μIU/mL比(7.78±0.98)μIU/ mL]下降,F,T3左甲状腺素钠组[(5.85±0.81)pmol/L比(4.34±0.67)pmol/L]和联合组[(5.63±0.54)pmol/L比(4.27±0.63)pmol/L]升高、 FT4左甲状腺素钠组[(13.22±1.56)pmol/L比(10.22±1.30)pmol/L]和联合组[(12.69±1.31)pmol/L比(9.89±1.12)pmol/L]升高(P<0.05)。治疗后 HAMA和 HAMD评分与治疗前相比,西酞普兰组[(12.60±1.35)分比(21.90±2.56)分]、[(12.57±1.61)分比(22.16±1.72)分]左甲状腺素钠组[(14.50±1.54)分比(21.30±2.39)分]、[(13.90±2.64)分比(22.93±1.85)分]和联合组[(8.36±1.73)分比(20.4,3±3.08)分]、[(8.26±1.63)分比(21.96±1.62)分]下降(P<0.05)。与西酞普兰组、左甲状腺素钠组相比,联合组 HAMA和 HAMD评分下降(P<0.05)。结论草酸艾司西酞普兰或左甲状腺素钠均可以缓解亚临床甲状腺功能减退伴焦虑抑郁病人的焦虑抑郁症状,联合用药疗效优于单药治疗。 相似文献
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Objective To analyze the rented factors leading to successful treatment of ectopic pregnancy by conservative therapy and to explore importance of this therapy. Methods 152 patients with ectopic pregnancy performed with conservative treatment were randomly recruited into a methotrexate plus Chinese medicine group, a 5-fluorouracil plus Chinese medicine group and a exclusive Chinese medicine group. The curative rate and side effect were observed in groups, and the relation between the treatment condition and the curative rate was analyzed. Results There was no difference in curative rate among groups, while the side effect in the exclusive Chinese medicine group was lower than other groups. It showed high curative rate in patients with two or more conditions of having mass less than 3 cm, the level of bloodβ-hCG less than 1000 IU/L, and the depth of posterior fomix effusion less than 1 cm. Conclusion Among the treatments of ectopic pregnancy, Chinese medicine has fewer side effects. Fully evaluation on the treatment condition can improve the curative rate. 相似文献
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医院管理层参加病陪人座谈会在医患沟通中的作用 总被引:2,自引:0,他引:2
医患关系是指在医疗活动中医生与患者之间心理行为的关系 ,它涉及医务人员、医疗单位和社会之间多方面的关系。医患间良好的沟通在医疗实践中极其重要 ,它可以保证患者充分享受权利和履行应尽的义务。同时 ,陪人提出的各方面的问题也促使医院改进工作 ,提高患者的满意度。 2 0 相似文献
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护理工作有很强的连续性,做好夜间护理工作至关重要,特别是胸外科病人大多数经受I全麻开胸的手术,病情较重,而且夜间病情又容易恶化,这就要求我们不但要有全面的知识和过硬的技术,而又还要有较强的责协.j和科学的管理方法,这样才能确保病人早日康复。善于观察、估计、分析病人的症状是临床护士最重要的业务素质之一,这一点在夜间单独值班时尤为重要。本文对胸外科病人夜间护理观察的重要性作如下总结。医护士应把对睡眠的护理做为夜间工作重点之一首先应注意医院环境对睡眠的影响,如减少噪音,为病人创造一个安静、舒适的休养环… 相似文献
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本次调查对30例已确诊的PHC和30例其他肿瘤及肛肠外科病例对照,采用PHA和ELISA检测方法,做了1:2配对的血清流行病学调查。结果显示:PHC病例HBV流行率90%,HBsAg阳性率56.67%,抗-HBc阳性率33.33%,抗-HBe阳性率35.29%,均显著高于对照(P﹤0.05~0.001)。相对危险性也分别是对照组的7.6、5、39和5.5倍。通过询问还发现PHC病例的肝病史、肝炎接触史,也都显著高于对照(P﹤0.001)。从而进一步验证了HBV感染与PHC发病的病因学联系。 相似文献
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Objective To analyze the rented factors leading to successful treatment of ectopic pregnancy by conservative therapy and to explore importance of this therapy. Methods 152 patients with ectopic pregnancy performed with conservative treatment were randomly recruited into a methotrexate plus Chinese medicine group, a 5-fluorouracil plus Chinese medicine group and a exclusive Chinese medicine group. The curative rate and side effect were observed in groups, and the relation between the treatment condition and the curative rate was analyzed. Results There was no difference in curative rate among groups, while the side effect in the exclusive Chinese medicine group was lower than other groups. It showed high curative rate in patients with two or more conditions of having mass less than 3 cm, the level of bloodβ-hCG less than 1000 IU/L, and the depth of posterior fomix effusion less than 1 cm. Conclusion Among the treatments of ectopic pregnancy, Chinese medicine has fewer side effects. Fully evaluation on the treatment condition can improve the curative rate. 相似文献
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Objective To analyze the rented factors leading to successful treatment of ectopic pregnancy by conservative therapy and to explore importance of this therapy. Methods 152 patients with ectopic pregnancy performed with conservative treatment were randomly recruited into a methotrexate plus Chinese medicine group, a 5-fluorouracil plus Chinese medicine group and a exclusive Chinese medicine group. The curative rate and side effect were observed in groups, and the relation between the treatment condition and the curative rate was analyzed. Results There was no difference in curative rate among groups, while the side effect in the exclusive Chinese medicine group was lower than other groups. It showed high curative rate in patients with two or more conditions of having mass less than 3 cm, the level of bloodβ-hCG less than 1000 IU/L, and the depth of posterior fomix effusion less than 1 cm. Conclusion Among the treatments of ectopic pregnancy, Chinese medicine has fewer side effects. Fully evaluation on the treatment condition can improve the curative rate. 相似文献
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本文对天津部分奶牛队643名职工,进行了临床和 HT、SAT、CFT、RBPT、ELISA 等血清学检测和皮内变态反应试验。查得血清阳性率7.93%(51/643),患病率为2.33%(15/643)。并且对阳性者分别按性别、年龄、接触奶牛年限、职业(工种)、血型等进行了分析。得出了感染与年龄、接触年限、职业(工种)、血型等在统计学上显著有关。指出:患布鲁氏菌病的奶牛是人畜间布鲁氏菌病流行的传染源,并指出以接触为主的传播途径和牛种布鲁氏菌为流行菌株。最后强调对重点人群布鲁氏菌病普查的重要性,并对今后的布鲁氏菌病防治工作提出了建议。 相似文献
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