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Pouliquen  M.  Denoual  M.  Jorel  C.  Radu  C.  Robbes  D.  Grand  J.  Awala  H.  Mintova  S.  Harnois  M.  Sagazan  O. de  Inoue  S.  Lebrasseur  E.  Yamada  K.  Okamoto  Y.  Mita-Tixier  A.  Mita  Y. 《Microsystem Technologies》2022,28(6):1313-1319
Microsystem Technologies - We demonstrate a new operation mode of thermal gas sensor based on thermal capacity extraction with identification algorithm. The system is a silicon microstructure...  相似文献   
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This study investigated the mechanism of right ventricular failure during bypass of the left side of the heart by precisely assessing right ventricular function with use of a conductance catheter. Bypass of the left side of the heart was established with a centrifugal pump in 10 mongrel dogs weighing 11 to 19 kg. Right ventricular function during left heart bypass was evaluated by two parameters that were both derived from measurement of relative change in right ventricular volume by the conductance catheter technique. One parameter was the right ventricular end-systolic pressure-volume relationship as a load-independent index, and the other was the peak right ventricular pressure-right ventricular stroke volume relationship as a "force-velocity relationship." These parameters were measured in both normal and failing hearts while afterload was increased by bilateral intrapulmonary balloon inflation. Moreover, changes in these relationships were observed by varying assist ratios of left heart bypass from 0% to 100%. Failing heart models were induced by normothermic aortic clamping for 20 minutes. The right ventricular end-systolic pressure-volume relationship in normal hearts did not change, irrespective of the assist ratio of left heart bypass, whereas that in failing hearts decreased from 4.25 +/- 1.41 mm Hg/ml without bypass of the left side of the heart to 3.53 +/- 1.30 mm Hg/ml after 100% assist of left heart bypass (p < 0.05). In the peak right ventricular pressure-right ventricular stroke volume relationship, right ventricular stroke volume was almost constant in normal hearts when afterload was increased regardless of the assist ratio of left heart bypass. Moreover, right ventricular stroke volume was maintained at a higher level during bypass of the left side of the heart compared with that without left heart bypass. However, that slope of the relationship in failing hearts was inversely linear and became significantly steeper after 100% assist of bypass of the left side of the heart compared with that without left heart bypass (-0.131 +/- 0.042 versus -0.051 +/- 0.038, p < 0.005). Therefore ++these two slopes of the relationship intersected at a point that was considered the critical point of afterload during bypass of the left side of the heart. In other words, right ventricular stroke volume was decreased by 100% left heart bypass above the critical point of afterload. In conclusion, this study demonstrates not only that bypass of the left side of the heart results in an increase in right ventricular stroke volume in both normal and failing hearts at the physiologic range of afterload, but also that right ventricular function against higher afterload is impaired by 100% assist of bypass of the left side of the heart in failing hearts.  相似文献   
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We address the balanced clustering problem where cluster sizes are regularized with submodular functions. The objective function for balanced clustering is a submodular fractional function, i.e., the ratio of two submodular functions, and thus includes the well-known ratio cuts as special cases. In this paper, we present a novel algorithm for minimizing this objective function (submodular fractional programming) using recent submodular optimization techniques. The main idea is to utilize an algorithm to minimize the difference of two submodular functions, combined with the discrete Newton method. Thus, it can be applied to the objective function involving any submodular functions in both the numerator and the denominator, which enables us to design flexible clustering setups. We also give theoretical analysis on the algorithm, and evaluate the performance through comparative experiments with conventional algorithms by artificial and real datasets.  相似文献   
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We investigated whether beta-amyloid (Abeta)-like immunoreactivity was seen in the brains of newborn piglets. The immunoreactivity for Abeta(1-42) and Abeta(1-40) proteins, but not Abeta precursor protein, was present in CD68-positive perivascular cells of the hippocampus and in parts of the meninges. It was colocalized with immunoreactivity for receptor for advanced glycation end product and tumor necrosis factor-alpha. The protein with a molecular mass of 27 kDa, which was recognized by the Abeta antibodies, was identified as triosephosphate isomerase (TPI) with sequence homology to Abeta peptides by N-terminal amino acid sequencing, mass fingerprint analysis using matrix-associated laser desorption/ionization mass spectrometry, and Western blotting. Western blotting assay also revealed that detectable expression of Abeta proteins were not seen in the piglet brains. These findings indicate that TPI with sequence homology to Abeta peptides accumulates in perivascular cells of the microglia/macrophage lineage located around arterial vessels of the newborn piglet hippocampus.  相似文献   
106.
Abstract— A red‐emitting phosphor, SrTiO3:Pr3+, for low‐voltage‐type FEDs and VFDs was developed by Futaba Corporation in 1996. The addition of Al or Ga is essential in the preparation of this phosphor because it improves the luminescence efficiency dramatically. For this impurity effect, Futaba Corporation proposed a charge‐compensation mechanism, which was supported by a recent observation of emission lines due to Al3+‐Pr3+ pairs. In addition, it was found that Al also works as a scavenger of planar defects, presumably SrO thin layers interleaved in the SrTiO3 lattice, by forming strontium aluminates. The latter mechanism suggests the possibility that a similar impurity effect can be found in materials with crystal structures, including alkaline‐earth oxide layers (Ruddlesden‐Popper phases).  相似文献   
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The effect of cold rolling on the superconducting properties was examined for amorphous Nb50Zr35Si15 and Nb70Zr15Si15 superconductors. Cold rolling to 10 to 20% reduction in thickness results in a rise of superconducting transition temperature (T c) and a decrease in transition width (T c), upper critical field gradient near , critical current density [J c(H)] and normal electrical resistivity (n). Changes of about 7% forT c 33% for T c, 12% for and 70% forJ c(H) are found. The rise ofT c upon cold rolling was considered to originate from the increase in the electron-phonon coupling constant () due to an increase in the electronic density of states at the Fermi level [N(E f)] and a decrease in the phonon frequency (), while the decreases in Tc,J c(H) and n were attributed to the decrease in fluxoid pinning force due to an increase in homogeneity in the amorphous structure. From the results described above, the following two conclusions were derived: (a) cold rolling causes changes in electronic and phonon-states in the quenched amorphous phase, and (b) deformation upon cold rolling occurs not only in the coarse deformation bands observable by optical microscopy, but also on a much finer scale comparable to the coherence length (7.7 nm).  相似文献   
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