Brain fMRI reactivity to smoking-related images before and during extended smoking abstinence.

[Correction Notice: An erratum for this article was reported in Vol 18(3) of Experimental and Clinical Psychopharmacology (see record 2010-11933-011). In the article the authors find it necessary to redefine the thresholding procedure used for data analyses, due to problems in the Brain Voyager software. This does not affect the main findings of the paper.] Reactivity to smoking-related cues may play a role in the maintenance of smoking behavior and may change depending on smoking status. Whether smoking cue-related functional MRI (fMRI) reactivity differs between active smoking and extended smoking abstinence states currently is unknown. We used fMRI to measure brain reactivity in response to smoking-related versus neutral images in 13 tobacco-dependent subjects before a smoking cessation attempt and again during extended smoking abstinence (52 ± 11 days) aided by nicotine replacement therapy. Prequit smoking cue induced fMRI activity patterns paralleled those reported in prior smoking cue reactivity fMRI studies. Greater fMRI activity was detected during extended smoking abstinence than during the prequit assessment subcortically in the caudate nucleus and cortically in prefrontal (BA 6, 9, 44, 46), primary somatosensory (BA 1, 2, 3), temporal (BA 22, 41, 42), parietal (BA 7, 40) anterior cingulate (BA 24, 32), and posterior cingulate (BA 31) cortex. These data suggest that during extended smoking abstinence, fMRI reactivity to smoking versus neutral stimuli persists in brain areas involved in attention, somatosensory processing, motor planning, and conditioned cue responding. In some brain regions, fMRI smoking cue reactivity is increased during extended smoking abstinence in comparison to the prequit state, which may contribute to persisting relapse vulnerability. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Pulsed laser deposition of organic and biological materials

We report on the deposition of soft matter thin films by Matrix Assisted Pulsed Laser Evaporation (MAPLE). In particular, thin layers of biological material (Bovine Serum Albumin) and polymers (polyfluorene) for medical and optoelectronic applications, were realized by laser irradiating a frozen solution containing a low amount of material diluted in a laser absorbing volatile solvent. The depositions were carried out varying different parameters as solvent–solute concentration, solvent nature, laser fluencies, etc. The optical, morphological, structural and spectroscopical properties were detected by means of different analyses as FTIR, photoluminescence, AFM and SDS.     

Effects of nutrient supplementation on fermentation kinetics, H2S evolution, and aroma profile in Verdicchio DOC wine production

Different yeast nutrient additions were studied for the 2008 and 2009 vintages of Verdicchio grape juice fermentation. Addition of yeast derivatives at the beginning of fermentation and/or different amounts of diammonium phosphate at various times within the first half of fermentation were examined, with initial yeast assimilable nitrogen concentrations set at 200 and 250 mg l^?1. Supplementation with glutathione in combination with this nitrogen addition was also evaluated. Fermentation rates were monitored throughout these fermentations carried out under different nutrient conditions. H₂S production during fermentation and synthesis of volatile compounds in the finished wines were quantified; the wines also underwent sensory evaluation. The fermentation kinetics were almost exclusively influenced by the inorganic nitrogen supplementation with diammonium phosphate. H₂S evolution was more affected by assimilable nitrogen than glutathione. Diammonium phosphate significantly reduced H₂S production, with a further reduction in the presence of yeast derivative. This nitrogen supplementation yielded higher concentrations of acetate esters, and in particular of isoamyl acetate (fruity aromas), which positively influences the analytical and aroma profile of wines and results in a general reduction in 2-phenylethanol production (floral aromas). Overall results (two harvesting times and vintages) indicate that the management with diammonium phosphate and yeast derivative supplementation improves the kinetics of fermentation and provides a good tool to reduce H₂S formation and increase the analytical and sensory quality of Verdicchio wine.     

Efficient analysis and experimental verification of substrate‐integrated slab waveguides for wideband microwave applications

This article presents a substrate integrated waveguide, named the substrate‐integrated slab waveguide (SISW), which exhibits a wide operation bandwidth. It consists of an integrated rectangular waveguide filled with a periodically perforated dielectric medium. An efficient procedure has been developed for the calculation of the dispersion diagram of SISWs, based on the Floquet theorem, in conjunction with the segmentation technique and the boundary‐integral–resonant‐mode‐expansion (BI‐RME) method. Numerical and experimental results confirm the performance of these waveguides and the efficiency of the analysis method. © 2005 Wiley Periodicals, Inc. Int J RF and Microwave CAE, 2005.     

Virtual agent multimodal mimicry of humans

This work is about multimodal and expressive synthesis on virtual agents, based on the analysis of actions performed by human users. As input we consider the image sequence of the recorded human behavior. Computer vision and image processing techniques are incorporated in order to detect cues needed for expressivity features extraction. The multimodality of the approach lies in the fact that both facial and gestural aspects of the user’s behavior are analyzed and processed. The mimicry consists of perception, interpretation, planning and animation of the expressions shown by the human, resulting not in an exact duplicate rather than an expressive model of the user’s original behavior.     

冷却剂丧失条件下钠冷快堆棒束传热的三维蒙特卡罗模拟方法

采用蒙特卡罗方法分析钠冷快堆在假想冷却剂丧失条件下燃料棒束的钠两相流传热问题。以分子运动理论的基本定律为基础，开发出替代宏观经验模型来分析反应堆棒束中的钠蒸发率和冷凝率的微观模型，且采用三维蒙特卡罗方法模拟分子的运动轨迹，分子间的碰撞率以及分子与棒束、分子与棒束组件盒壁的碰撞率。对包壳干涸区的再浸润现象用动力膜模型描述，并计算了通过液膜的液体速度分布和平均液膜速度，对于从冷凝液膜蒸发的钠分子则被重新记为蒙特卡罗计算的源项。用微观和宏观模型相结合的方法数字模拟了德国卡斯鲁尔研究中心的堆外钠沸腾实验。     

Analytical framework for end-to-end design of optical burst-switched networks

This paper presents an analytical model of TCP throughput in optical burst-switched (OBS) networks. Several parameters characterize this system and influence the network design process, such as the assembly time, the access bandwidth, the burst loss rate, and they are taken into account in the formulation of TCP send rates. Moreover burst loss is considered a consequence of contention in core nodes and it is formulated in relation to a quite general core node architecture. The novelty of the work is represented by the possibility of analytically representing the whole end-to-end connection so that a fast and effective tool to evaluate the relationships between network and access design is provided. An application example is given to prove the practical significance of the approach. Simulation results are provided to validate the model and the related assumptions.     

Modified friction factor correlation for CICC’s based on a porous media analogy

The first cool-down of the EDIPO (European DIPOle) test facility is foreseen to take place in 2011 by means of the existing 1.2 kW cryoplant at EPFL-CRPP Villigen. In this work, the thermo-hydraulic analysis of the EDIPO cool-down is performed in order both to assess the its duration and to optimize the procedure. The cool-down is driven by the helium flowing in both the outer cooling channel and in the windings connected hydraulically in parallel. We take into account limitations due to the pressure drop in the cooling circuit and the refrigerator capacity as well as heat conduction in the iron yoke. Two schemes of the hydraulic cooling circuit in the EDIPO windings are studied (coils connected in series and coils connected in parallel). The analysis is performed by means of an analytical model complemented by and numerical model. The results indicate that the cool-down to 5 K can be achieved in about 12 days.     

Pre-emptive versus non-pre-emptive real time scheduling in intelligent mobile robotics

Autonomous and semi-autonomous mobile robots have to perform a multiplicity of concurrent activities in order to carry out useful tasks in unstructured human-populated environments. Even if it is commonly accepted that a successful accomplishment of assigned tasks requires some sort of real time capability to quickly react and adapt to environmental changes, it is not clear which operating system support is best suited for the scheduling and synchronizing of concurrent activities with different timing requirements. This paper discusses this problem, comparing two different real time scheduling policies for autonomous robot applications: pre-emptive rate monotonic and non pre-emptive Earliest Deadline First (EDF). Experimental results are presented and evaluated.