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41.
Luisa Sánchez Brea Noelia Barreira Rodríguez Antonio Mosquera González Hugo Pena-Verdeal Eva Yebra-Pimentel Vilar 《Pattern Analysis & Applications》2018,21(2):563-577
Hyperaemia is an excess of blood in a tissue that causes the appearance of an unusual red hue in the affected area. It is a common occurrence in the bulbar conjunctiva, where it can be related to multiple pathologies, such as conjunctivitis or dry eye syndrome. Specialists grade hyperaemia by means of a tedious, subjective, non-repeatable and time-consuming process. These drawbacks can be solved with the automatisation of the process by means of image processing techniques. The automatic segmentation of the conjunctiva is an important part of the process, as it ensures the absence of noise in posterior stages of the methodology. However, there are several issues of illumination and focus in the input videos that difficult the process. In this work, several segmentation algorithms are proposed and compared in order to obtain an accurate location of the bulbar conjunctiva. 相似文献
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Cenobio-Galindo Antonio de Jesus Pimentel-González Diana Jaqueline Del Razo-Rodríguez Oscar Enrique Medina-Pérez Gabriela Carrillo-Inungaray María Luisa Reyes-Munguía Abigail Campos-Montiel Rafael Germán 《Food science and biotechnology》2019,28(5):1553-1561
Food Science and Biotechnology - The use of unconventional sources is very relevant in the food area. In the present study the development of active films with the addition of bioextract (BE) or... 相似文献
43.
Italia Falcone Fabiana Conciatori Chiara Bazzichetto Emilio Bria Luisa Carbognin Paola Malaguti Gianluigi Ferretti Francesco Cognetti Michele Milella Ludovica Ciuffreda 《International journal of molecular sciences》2020,21(22)
Breast cancer was one of the first malignancies to benefit from targeted therapy, i.e., treatments directed against specific markers. Inhibitors against HER2 are a significant example and they improved the life expectancy of a large cohort of patients. Research on new biomarkers, therefore, is always current and important. AXL, a member of the TYRO-3, AXL and MER (TAM) subfamily, is, today, considered a predictive and prognostic biomarker in many tumor contexts, primarily breast cancer. Its oncogenic implications make it an ideal target for the development of new pharmacological agents; moreover, its recent role as immune-modulator makes AXL particularly attractive to researchers involved in the study of interactions between cancer and the tumor microenvironment (TME). All these peculiarities characterize AXL as compared to other members of the TAM family. In this review, we will illustrate the biological role played by AXL in breast tumor cells, highlighting its molecular and biological features, its involvement in tumor progression and its implication as a target in ongoing clinical trials. 相似文献
44.
Rossella Gratton Paola Maura Tricarico Adamo Pio dAdamo Anna Monica Bianco Ronald Moura Almerinda Agrelli Lucas Brando Luisa Zupin Sergio Crovella 《International journal of molecular sciences》2020,21(22)
Notch pathway is a highly conserved intracellular signaling route that modulates a vast variety of cellular processes including proliferation, differentiation, migration, cell fate and death. Recently, the presence of a strict crosstalk between Notch signaling and inflammation has been described, although the precise molecular mechanisms underlying this interplay have not yet been fully unravelled. Disruptions in Notch cascade, due both to direct mutations and/or to an altered regulation in the core components of Notch signaling, might lead to hypo- or hyperactivation of Notch target genes and signaling molecules, ultimately contributing to the onset of autoinflammatory diseases. To date, alterations in Notch signaling have been reported as associated with three autoinflammatory disorders, therefore, suggesting a possible role of Notch in the pathogenesis of the following diseases: hidradenitis suppurativa (HS), Behçet disease (BD), and giant cell arteritis (GCA). In this review, we aim at better characterizing the interplay between Notch and autoinflammatory diseases, trying to identify the role of this signaling route in the context of these disorders. 相似文献
45.
Fernanda Andreola Isabella Lancellotti Tiziano Manfredini Luisa Barbieri 《International Journal of Applied Ceramic Technology》2020,17(1):22-31
The circular economy in the area of waste management implies their re-use as a raw material in different production cycles. Both the qualitative and quantitative characteristics of the residues from the agro sector and those of the products of the ceramics sector make possible to think of a feasible application. This review will illustrate some examples of recycling of residues deriving from animal and vegetable sectors (and two post consume products, spent coffee grounds, and packaging glass cullet), studied by the authors, falling within the concept of urban and agricultural sustainable development. Not only the most traditional products such as glass-ceramics, glazes, bricks, but also the most innovative lightweight aggregates for plant structures or in and out soil cultivation, as well as additives such as deflocculants for ceramic suspensions, which will be illustrated from the design/production, characterization, and comparison with commercial products. 相似文献
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Lara Piasenzotto Luisa Gracco Lanfranco Conte 《Journal of the science of food and agriculture》2003,83(10):1037-1044
The assessment of the botanical origin of unifloral honeys is an important application in food control. The current official methods mainly use pollen analysis. The aim of this paper is to present an SPME analytical approach to the study of honey volatiles. Honey samples (40) obtained from hive sites in different regions of Italy were analysed. The samples had six different botanical origins: citrus (five), chestnut (10), eucalyptus (eight), lime tree (11), thyme (two) and dandelion (four). Melissopalynological analysis was also performed. Identification of volatile compounds was carried out by SPME/GC/MS analysis, and quantitative evaluation was done by SPME/GC/FID analysis for compounds with well‐resolved peaks. Using the SPME method, all samples with the same botanical origin gave remarkably similar GC profiles. Some volatile compounds were found only in specific floral source honey samples and thus could be interesting for use as markers. Copyright © 2003 Society of Chemical Industry 相似文献
50.
Luciana Cerioni María de los Ángeles Lazarte Josefina María Villegas Luisa Rodríguez-MontelongoSabrina Inés Volentini 《Food microbiology》2013
Several oxidizing compounds such as sodium hypochlorite (NaClO) and hydrogen peroxide (H2O2) are used to control postharvest decay in fresh fruit due to their antimicrobial effects. Here, we applied these compounds in vitro, in the presence of CuSO4, against Penicillium expansum, causal agent of apple blue mold. MICs were 50 mg L−1 and 400 mmol L−1 for NaClO and H2O2, respectively, when these compounds were individually applied to conidia suspensions during 2 min. A combined oxidative treatment (OT) consisting on an incubation with 1 mg L−1 NaClO and 200 mmol L−1 H2O2, in the presence of 6 mmol L−1 CuSO4, inhibited growth, conidial germination and fungal infectivity on apple. The fractional inhibitory concentration index for the interaction between NaClO and H2O2 in the OT was 0.52 indicating a synergistic effect of the oxidizing compounds. These results suggest that the OT could be an interesting alternative for apple diseases postharvest control. 相似文献