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81.
Ragnhild E. Aune Miyuki Hayashi Keiji Nakajima Seshadri Seetharaman 《JOM Journal of the Minerals, Metals and Materials Society》2002,54(11):62-69
The optimization of metallurgical processes requires reliable data of the slag phase. This paper focuses on three properties
that are relevant to heat and mass-transfer calculations — viscosities,thermal diffusivities, and surface tensions of silicate melts. A brief account of the experimental techniques used for the
measurements of these properties, with special reference to the work carried out in the Division of Metallurgy, Royal Institute
of Technology, Stockholm, Sweden, are presented, along with the advantages and limitations. As these properties are structure-oriented,
the impact of structure on these properties is also presented. The paper is intended as a state-of-the-art review of the subject. 相似文献
82.
H Minagawa Y Liu T Yoshida Y Hidaka Y Toh R Mori 《Canadian Metallurgical Quarterly》1997,41(7):545-551
A clinical isolate of herpes simplex virus 1 (TN-1) from a stromal keratitis patient was found to be defective in the glycoprotein C (gC) gene (UL44), thus resulting in the production of truncated gC upon infection. To study the pathogenetic role of truncated gC, we prepared a recombinant LTN-8 derived from TN-1 with deletions of the 1.5 kilobase pairs of the gC gene including the initiation codon. A penetration assay revealed LTN-8 to be less efficient in its penetration ability than TN-1, the laboratory strain KOS and RTN-1-20-3, a recombinant derived from TN-1 with the KOS gC gene. The penetration of LTN-8 was facilitated by the addition of TN-1-infected culture medium. TN-1 virus preparations had no hemagglutinating activity. However, the animals infected with TN-1 did develop hemagglutination inhibition (HI) antibodies. The LTN-8-infected animals did not develop HI antibodies. The pathogenicity in BALB/c mice following either corneal, intraperitoneal or intracerebral inoculation did not significantly differ among TN-1, RTN-1-20-3 or LTN-8. Our results indicate that truncated gC was sufficient for the induction of HI antibodies and was also able to facilitate penetration in vitro. Although truncated gC might be a virulence factor acting as a decoy, both truncated gC and intact gC had little effect on the outcome following intracerebral, intraperitoneal or corneal inoculation. 相似文献
83.
James A. Cheshire Paul A. Longley Keiji Yano Tomoki Nakaya 《Papers in Regional Science》2014,93(3):539-555
This paper uses an extended case study of Japan to illustrate how surnames, or family names, can be used as a basis for regionalization. We undertake a comparison between inductively surname regions of Japan with areal geographies based upon both contemporary and historical prefecture (administrative) units. The work is seen as using highly disaggregate framework data to evaluate the integrity of the areal units that are used in regional science. It also is relevant to understanding population distributions, past and present, and the consequences of local, regional and national residential mobility and migration. 相似文献
84.
Tie?Liu Qiang?WangEmail author Hong-Wei?Zhang Chang-Sheng?Lou Keiji?Nakajima Ji-Cheng?He 《Journal of Materials Science》2011,46(6):1628-1634
The effects of high magnetic fields on the solidification microstructure of Al–Si alloys were investigated. Al–7.2 wt%Si and
Al–11.8 wt%Si alloys were solidified in various high magnetic fields at different cooling rates. The secondary dendrite arm
spacing (SDAS) of the primary Al dendrites and the lamellar spacing (LS) of the eutectics were measured. It was found that
the application of a high magnetic field could decrease the SDAS of the primary Al dendrites in Al–7.2 wt%Si alloys and the
LS of the eutectics in Al–11.8 wt%Si alloys. The effects of the high magnetic field on the SDAS decreased with increasing
cooling rate. The decrease in the SDAS and LS can be attributed to the decrease of the solute diffusivity in the liquid ahead
of the solid/liquid interface during the growth of the dendrite and eutectic. This decrease is caused by the high magnetic
field which can damp the convection and avoid its contributions to the diffusion. 相似文献
85.
Yukari Totsuka Takashi Higuchi Toshio Imai Akiyoshi Nishikawa Takehiko Nohmi Tatsuya Kato Shuich Masuda Naohide Kinae Kyoko Hiyoshi Sayaka Ogo Masanobu Kawanishi Takashi Yagi Takamichi Ichinose Nobutaka Fukumori Masatoshi Watanabe Takashi Sugimura Keiji Wakabayashi 《Particle and fibre toxicology》2009,6(1):1-11
Background
Recently, manufactured nano/microparticles such as fullerenes (C60), carbon black (CB) and ceramic fiber are being widely used because of their desirable properties in industrial, medical and cosmetic fields. However, there are few data on these particles in mammalian mutagenesis and carcinogenesis. To examine genotoxic effects by C60, CB and kaolin, an in vitro micronuclei (MN) test was conducted with human lung cancer cell line, A549 cells. In addition, DNA damage and mutations were analyzed by in vivo assay systems using male C57BL/6J or gpt delta transgenic mice which were intratracheally instilled with single or multiple doses of 0.2 mg per animal of particles.Results
In in vitro genotoxic analysis, increased MN frequencies were observed in A549 cells treated with C60, CB and kaolin in a dose-dependent manner. These three nano/microparticles also induced DNA damage in the lungs of C57BL/6J mice measured by comet assay. Moreover, single or multiple instillations of C60 and kaolin, increased either or both of gpt and Spi- mutant frequencies in the lungs of gpt delta transgenic mice. Mutation spectra analysis showed transversions were predominant, and more than 60% of the base substitutions occurred at G:C base pairs in the gpt genes. The G:C to C:G transversion was commonly increased by these particle instillations.Conclusion
Manufactured nano/microparticles, CB, C60 and kaolin, were shown to be genotoxic in in vitro and in vivo assay systems. 相似文献86.
87.
Male Fischer 344 rats were subcutaneously injected with azoxymethane (AOM) twice weekly at a dose of 15 mg/kg and were fed with freeze-dried (FD) samples of beer brewed without hops (non-hops beer), beer with hops at 4 times the amount of regular lager beer (x 4-hops beer), and isomerized hop extract (IHE) for the whole experimental period (I/PI) or for the post-initiation period (PI) only. Feeding FD beer samples at a dose of 1% significantly decreased the number of aberrant cryp foci (ACF) in the PI protocol over five weeks.x4-hops beer showed stronger inhibitory effects on the development of the numbers of aberrant crypts per focus and large ACF with four or more crypts than non-hops beer. Feeding IHE to rats at a dose of 0.01% or 0.05% in either the I/PI or PI experiment significantly reduced the numbers of ACF. Prostaglandin E2 (PGE2) levels in colonic mucosa of AOM-treated rats were significantly reduced by feeding of IHE. PGE2 production induced by lipopolysaccharide/interferon-gamma (LPS/IFN-gamma) in RAW264.7 cells was also reduced by treatment with IHE and isohumulone in a dose-dependent manner. These observations suggest that isohumulones show chemopreventive effects on ACF formation in rat colon by inhibiting the production of PGE2. 相似文献
88.
Terry Wall Yinghui Liu Chris Spero Liza Elliott Sameer Khare Renu Rathnam Farida Zeenathal Behdad Moghtaderi Bart Buhre Changdong Sheng Raj Gupta Toshihiko Yamada Keiji Makino Jianglong Yu 《Chemical Engineering Research and Design》2009,87(8):1003-1016
Oxyfuel combustion is seen as one of the major options for CO2 capture for future clean coal technologies. The paper provides an overview on research activities and technology development through a fundamental research underpinning the Australia/Japan Oxyfuel Feasibility Project. Studies on oxyfuel combustion on a pilot-scale furnace and a laboratory scale drop tube furnace are presented and compared with computational fluid dynamics (CFD) predictions. The research has made several contributions to current knowledge, including; comprehensive assessment on oxyfuel combustion in a pilot-scale oxyfuel furnace, modifying the design criterion for an oxy retrofit by matching heat transfer, a new 4-grey gas model which accurately predicts emissivity of the gases in oxy-fired furnaces has been developed for furnace modelling, the first measurements of coal reactivity comparisons in air and oxyfuel at laboratory and pilot-scale; and predictions of observed delays in flame ignition in oxy-firing. 相似文献
89.
Y Sakai H Minagawa T Ishibashi H Inomata R Mori 《Canadian Metallurgical Quarterly》1994,208(3):157-160
The antibody responses of 65 volunteers receiving an i.d. regimen (0.1 ml given at two sites on days 0, 3, 7 and 0.1 ml given at one site on days 30 and 90) were compared with the control group of 35 volunteers receiving the standard i.m. regimen. By day 14, seroconversion was observed in all vaccinees in both groups. Geometric Mean Titers remained higher than 0.5 IU/ml throughout the study period. At the end of the observation period on day 365, antibodies persisted in all subjects. The multisite i.d. PCEC regimen has been proved as immunogenic as the standard i.m. regimen. Both regimens were well tolerated. Thus, it would be the effective and cheapest available rabies post-exposure treatment using tissue culture vaccine. 相似文献
90.
Variation of Fructooligosaccharides and their Metabolizing Enzymes in Onion Bulb (Allium cepa L. cv. Tenshin) During Long-term Storage 总被引:1,自引:0,他引:1
Noureddine Benkeblia Keiji Ueno Shuichi Onodera Norio Shiomi 《Journal of food science》2005,70(3):S208-S214
ABSTRACT: The objective of this study was to assess the status of fructooligosaccharides (FOS) in onion bulbs ( Allium cepa L. cv. Tenshin) and their metabolizing-enzymes—1-fructoexohydrolase (1-FEH), 1-kestose hydrolyzing enzyme (1-KH), fructan:fructan 1F -fructosyltransferase (1-FFT) and fructan:fructan 6G -fructosyltransferase (6G-FFT)—during storage at 15°C. Fructose varies slightly, whereas 1-kestose peaked after 6 wk and then decreased progressively during the last 18 wk of storage. Lower degree of polymerization (DP) 3 to 6) FOS, higher (DP 7 to 12) FOS, total FOS, and total carbohydrates showed similar and close patterns during 24 wk. They varied slightly at the beginning of the storage period; afterward they decreased progressively and regularly during the last 20 wk of storage. 1-FEH and 1-KH activities were low but peaked abruptly after 12 and 16 wk, respectively, after which they decreased to levels higher (1-FEH) or similar (1-KH) to those observed at the beginning of the storage. Surprisingly, 1-FFT activity showed similar pattern to the variation of 1-KH hydrolyzing activity; on the other hand, 6G-FFT, although higher, was stable during 16 wk but decreased after that. The results allowed us to associate FOS to the dormancy and sprouting states, and the peaks of the degrading enzymes were shown to signal the release of dormancy of onion bulb. 相似文献