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S Kurotobi H Naito T Sano J Arisawa T Matsushita M Takeuchi S Kogaki S Okada 《Canadian Metallurgical Quarterly》1998,67(1):55-63
The highly reactive and cytotoxic hydroxyl radical (OH) was found by electrochemical detection to be produced in reactions involving hydrogen peroxide (H2O2) and the nitric oxide (NO) donor diethylamine- NO complex. Using aromatic hydroxylation of salicylate as a specific indicator of OH, three salicylate hydroxylation products were identified; catechol, 2,3- and 2,5-dihydroxybenzoic acid. Four additional compounds were detected but not identified. The interactions of H2O2 and NO represent a biologically feasible reaction mechanism that can account for OH-induced damage in cellular environments where transition metal ions are unavailable for participation in the superoxide-mediated Fenton reaction. The ability of the NO/H2O2 complex to generate OH independently of iron or other transition metals provides a new focus for studies concerned with the origin of tissue-specific damage caused by oxygen-derived species. 相似文献
44.
T Maruo S Yoshida T Samoto Y Tateiwa X Peng S Takeuchi S Motoyama 《Canadian Metallurgical Quarterly》1998,19(6):494-504
Expression of squamous cell carcinoma (SCC) antigen emerged concurrently with squamous formation of the uterine cervix and increased during the neoplastic transformation of the cervical squamous epithelium. SCC antigen expression differed considerably among the histomorphologic cell types of cervical carcinoma. Large cell nonkeratinizing carcinoma contained high levels of the antigen. In contrast, no appreciable expression of SCC antigen was observed in small cell nonkeratinizing carcinoma. The pattern of SCC antigen expression closely coincided with EGF receptor (EGF-R) expression in cervical squamous neoplasia. This suggests that the expression of SCC and EGF-R in cervical carcinoma is related to the differentiation or dedifferentiation processes of the tumor cells. SCC production by CaSki cervical epidermoid carcinoma cells was stimulated by EGF. It seems likely that an autocrine system, in which EGF serves as the signal, may exist in cervical squamous carcinoma. 17beta-estradiol and L-triiodothyronine were found to upregulate EGF-R expression, proliferative potential and SCC production in the CaSki cervical carcinoma cells. 相似文献
45.
The implementation on the vector processor of Incomplete LU factorization in the Preconditioned Conjugate Gradient method and other Preconditioned CG-like methods for the numerical solutions of the partial differential equations is discussed. For sufficient vectorization, a variant of the standard 5-point difference scheme for 2-dimensional problems is introduced. The convergence property of ILU factorization for this variant is examined in comparison with that vectorized with the usual hyperplane ordering method for the standard 5-point difference scheme on the vector processor. The efficiency and effectiveness of this factorization for the variant of the difference scheme is demonstrated through several computational experiments. 相似文献
46.
Kourogi M. Widiyatomoko B. Takeuchi Y. Ohtsu M. 《Quantum Electronics, IEEE Journal of》1995,31(12):2120-2126
The limit of optical frequency comb (OFC) generation (i.e., the limit of frequency difference measurement) due to the material dispersion in the EO crystal is experimentally studied. By using a modified monolithic OFC generator, we observed the OFC spectrum, and confirmed that the envelope of the OFC around 780 nm extended to a span as wide as 16 nm (or 7.6 THz) reaching the limit of the OFC generation. We also proposed a method of stabilizing the Fabry-Perot cavity for the monolithic OFC generator 相似文献
47.
Manabu Sato Tatsuo Yamamoto Toshiyasu Meguro Kazuhiko Yamanouchi 《Sensors and actuators. B, Chemical》1994,20(2-3):205-212
The sensitivity, transient response and sensitivity mechanism of a surface acoustic wave humidity sensor using porous anodically oxidized aluminium (alumina) films as mechanical interfaces have been studied theoretically and experimentally. It is found that the sensitivity of alumina films of 1.0 μm thickness is -0.034 m/(s %RH) and is the same order as that of polyimide films. The transient response of alumina films to humidity is about one order faster than that of polyimide films. For the sensitivity mechanism, the phase-velocity change is attributed to the mechanical perturbation caused by the absorption of water molecules. The equivalent density change of alumina films between 0 and 100%RH is about 0.7%. In addition, the actual stiffness constants of alumina films are two orders less than those of bulk alumina. 相似文献
48.
Kazuko Satake Ai Katayama Hideki Ohkoshi Takeshi Nakahara Takashi Takeuchi 《Sensors and actuators. B, Chemical》1994,20(2-3):111-117
Oxide semiconductors have been examined to develop NOx sensors for exhaust monitoring. Titania doped with trivalent elements, such as Al3+, Sc3+, Ga3+ or In3+, has a good sensitivity and selectivity to NO between 450 and 550 °C, and shows rapid response. A sensor probe for monitoring exhaust NOx has been fabricated. Many kinds of interference gases, such as C3H6, CO and SO2, have been found to have only a slight influence on the sensor response to NO. The influence of O2 and H2O is also negligible, except for the cases of 0% H2O and fuel-rich conditions. In accordance with these results, the sensor probe operates satisfactority in the exhaust gas of various combustion conditions without interference from the various kinds of gas species in the exhaust gases. 相似文献
49.
Machine Learning - Graphs are versatile tools for representing structured data. As a result, a variety of machine learning methods have been studied for graph data analysis. Although many such... 相似文献
50.
The optical properties of O2
– centres in KClNaCl mixed crystals were investigated. The timeresolved spectra and the fluorescence decay time are shown. From the measurements of the radiative decay time, the oscillator strength of the absorption,f
ab=0.045, the oscillator strength of the fluorescence,f
fluo=0.019, and the activation energy E=0.22 eV for the O2
– centre in KClNaCl were determined. 相似文献