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71.
AIMS: To test the hypothesis that screening for alcohol-related disorders in a general hospital with questionnaires generates a target group of patients for alcohol counselling which differs from patients referred by physicians' routine clinical practice. DESIGN: A prospective study with follow-up after 12 months. SETTING: Medical and surgical wards of a general hospital. PARTICIPANTS: A sample of 298 patients detected by screening questionnaires (CAGE, MAST) was compared with a sample of 87 patients referred by physicians. MEASUREMENTS: The main measurements were a diagnostic interview (SCAN), two questionnaires to estimate the severity of dependence and the motivation to change drinking behaviour (RCQ, LAS), and socio-demographic variables. Outcome criteria were utilization of remedial programmes, decreases in hazardous and excessive drinking and abstinence rates. FINDINGS AND CONCLUSIONS: Patients referred by physicians were more often separated and unemployed, were more likely to be alcohol-dependent and to be more severely dependent, had a higher rate of alcohol-related diseases as reasons for admission, were more often motivated to change drinking behaviour, had a higher participation rate in remedial programmes and more often exhibited improvements in drinking behaviour compared with the sample identified by screening questionnaires. However, there was evidence of improvements in drinking in both samples. Data show that while screening reaches a less problematic sample with lower motivation to change, it is a worthwhile activity which extends the spectrum of patients eligible for brief interventions.  相似文献   
72.
Dairy farmers do not take full advantage of opportunities available for genetic improvement through use of artificial insemination, perhaps because economic advantages of good sire selection may not be fully recognized or understood. This study was undertaken to document differences between use of AI and non-AI bulls and to develop prediction equations to compare lifetime economic merit of future progeny from alternative sire selection policies. We describe the use of two methods of measuring lifetime economic merit, with and without adjustment for opportunity cost of a postponed replacement. Comparison of lifetime relative net income adjusted for opportunity cost on groups of cows sired by different kinds of bulls showed that daughters of proven AI bulls generated $148 and $120 more lifetime net income under fluid and manufactured milk market conditions than daughters of non-AI bulls. Daughters of proven AI bulls produced $60 more than daughters of AI young sires in progeny testing programs at the time of daughter conception. We developed prediction equations from combinations of genetic evaluations for production, productive life, SCS, and linear type traits on sires to predict lifetime relative net income of progeny produced from alternative sire selection strategies. Prediction equations explained 14 to 18% of variation in relative net income (not adjusted for opportunity cost), but herd and year of first freshening accounted for considerably more variation than did genetic evaluations on the sire of the cow. Finally, two independent data sets were used to develop and test predictions of lifetime relative net income adjusted for opportunity cost using genetic evaluations based on the eight traits included in the Merit indexes for the sire of each cow. Prediction equations from odd numbered herds were used to predict lifetime economic merit in even numbered herds and vice versa. Coefficients of determination ranged from 0.088 to 0.103 and averaged 0.004 higher than prediction equations with Net or Fluid Merit. Accuracy of predictions showed that Net and Fluid Merit were robust and useful indexes that accurately identified bulls whose daughters generated highest lifetime economic merit.  相似文献   
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