On a generalized approach to manufacturing energy efficiency

Energy efficiency has become a very significant factor, requiring its inclusion in the manufacturing decision-making attributes. This paper proposes a generalized approach to manufacturing energy efficiency. The basic element of the approach is the division of energy efficiency definition and study into four manufacturing levels, namely process, machine, production line, and factory. Process-level definitions are provided for the majority of manufacturing processes. A machine-level study indicates and solves difficulties, generated by the workpiece geometry, and points out the interaction with the process level through factors, such as the process time. Moreover, machine tool peripherals are responsible for a significant portion of the consumed energy, and classification based on the dependence of their consumption on process variables is required. Studies made on the production line and factory levels show that energy efficiency, at these levels, is heavily dependent on production planning and scheduling and can be improved through the appropriate utilization of machines, with the inclusion of shutdown and eco-modes. Finally, a case study is presented, showing that many of the difficulties towards the optimization of energy efficiency can be dealt with successfully, using the proposed generalized approach.     

Sign boundary and hand articulation feature recognition in Sign Language videos

Machine Translation - In this paper we present a recommendation system for (semi-)automatic annotation of sign language videos exploiting deep learning techniques, which handle handshape...     

A Systematic Review and Meta-Analysis of Pharmacogenetic Studies in Patients with Chronic Kidney Disease

Chronic kidney disease (CKD) is an important global public health problem due to its high prevalence and morbidity. Although the treatment of nephrology patients has changed considerably, ineffectiveness and side effects of medications represent a major issue. In an effort to elucidate the contribution of genetic variants located in several genes in the response to treatment of patients with CKD, we performed a systematic review and meta-analysis of all available pharmacogenetics studies. The association between genotype distribution and response to medication was examined using the dominant, recessive, and additive inheritance models. Subgroup analysis based on ethnicity was also performed. In total, 29 studies were included in the meta-analysis, which examined the association of 11 genes (16 polymorphisms) with the response to treatment regarding CKD. Among the 29 studies, 18 studies included patients with renal transplantation, 8 involved patients with nephrotic syndrome, and 3 studies included patients with lupus nephritis. The present meta-analysis provides strong evidence for the contribution of variants harbored in the ABCB1, IL-10, ITPA, MIF, and TNF genes that creates some genetic predisposition that reduces effectiveness or is associated with adverse events of medications used in CKD.     

Microbiological and physicochemical characterisation of green table olives of Halkidiki and Conservolea varieties processed by the Spanish method on industrial scale

The microbiological and physicochemical changes of industrially fermented Halkidiki and Conservolea green table olives were determined. Samples were analysed to monitor the population of lactic acid bacteria (LAB), yeasts and Enterobacteriaceae, together with changes in pH, acidity, salinity, colour, lactic acid, acetic acid and ethanol. LAB and yeast species diversity was evaluated at the beginning (1 day), middle (75 days) and final (135 days) stages of fermentation by RAPD-PCR genomic fingerprinting. Results revealed vigorous lactic acid processes as indicated by the dominance of LAB over yeasts. No Enterobacteriaceae could be detected after 30 days. Lactiplantibacillus plantarum (formerly Lactobacillus plantarum) dominated in the beginning of fermentation in both varieties. In the end, Lactiplantibacillus pentosus (formerly Lactobacillus pentosus) and Pediococcus ethanolidurans prevailed in Halkidiki and Conservolea varieties, respectively. As for yeasts, Kluyveromyces lactis/marxianus and Pichia manshurica prevailed at the onset of fermentation in Halkidiki and Conservolea varieties, whereas in the end Pichia membranifaciens dominated in both varieties.     

CoopStor: a cooperative reliable and efficient data collection protocol in fault and delay tolerant wireless networks

Wireless Networks - Internet of things consist in the deployment of constrained and battery-powered devices with a radio interface. Most industrial applications require to respect strict...     

A novel hybrid process design for efficient recovery of hydrophilic ionic liquids from dilute aqueous solutions

Ionic liquids (ILs) have received much attention in both academia and industries due to their superior performance in many applications. Efficient recovery/recycling of ILs from their dilute aqueous solutions is essential for the acceptance and implementation of many IL-based technologies by industry. In this work, a practical and cost-effective hybrid process design method that combines aqueous two-phase extraction, membrane separation, and distillation operating at their highest efficiencies is proposed for the recovery of hydrophilic ILs from dilute aqueous solutions. The application of this hybrid process design method is illustrated through case studies of recovering two hydrophilic ILs, n-butylpyridinium trifluoromethanesulfonate ([C₄Py][TfO]) (CAS number: 390423-43-5) and 1-butyl-3-methylimidazolium chloride ([C₄mIm][Cl]) (CAS number: 79917-90-1), from their dilute aqueous solutions. For the recovery of 10 wt.% [C₄Py][TfO] from aqueous solution, the hybrid process using (NH₄)₂SO₄ as the salting-out agent could reduce the total annual cost (TAC) and energy consumption by 57% and 91%, respectively, compared with the pure distillation processes. In the case of recovering 10 wt.% [C₄mIm][Cl] from aqueous solution, the reduction in TAC and energy savings of the hybrid process with salting-out agent (NH₄)₂SO₃ could reach 49% and 87%, respectively, compared with the pure distillation process. Furthermore, uncertainty analysis through Monte Carlo simulations show that the proposed hybrid process design is more robust to uncertainties in energy prices and other material (e.g., equipment and solvent) costs.     

New facets of mobile botnet: architecture and evaluation

It is without a doubt that botnets pose a growing threat to the Internet, with DDoS attacks of any kind carried out by botnets to be on the rise. Nowadays, botmasters rely on advanced Command and Control (C&C) infrastructures to achieve their goals and most importantly to remain undetected. This work introduces two novel botnet architectures that consist only of mobile devices and evaluates both their impact in terms of DNS amplification and TCP flooding attacks, and their cost pertaining to the maintenance of the C&C channel. The first one puts forward the idea of using a continually changing mobile HTTP proxy in front of the botherder, while the other capitalizes on DNS protocol as a covert channel for coordinating the botnet. That is, for the latter, the messages exchanged among the bots and the herder appear as legitimate DNS transactions. Also, a third architecture is described and assessed, which is basically an optimized variation of the first one. Namely, it utilizes a mixed layout where all the attacking bots are mobile, but the proxy machines are typical PCs not involved in the actual attack. For the DNS amplification attack, which is by nature more powerful, we report an amplification factor that fluctuates between 32.7 and 34.1. Also, regarding the imposed C&C cost, we assert that it is minimal (about 0.25 Mbps) per bot in the worst case happening momentarily when the bot learns about the parameters of the attack.     

Backward difference formulae for Kuramoto–Sivashinsky type equations

We analyze the discretization of the periodic initial value problem for Kuramoto–Sivashinsky type equations with Burgers nonlinearity by implicit–explicit backward difference formula (BDF) methods, establish stability and derive optimal order error estimates. We also study discretization in space by spectral methods.