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991.
The Cr:Fe ratio (chromium-to-iron mass ratio) of chromite affects the production of chrome-based ferroalloys. Although the lit-erature contains numerous reports related to the magnetic separation of di... 相似文献
992.
Elucidating the Catalytic Subunit Composition of Distinct Proteasome Subtypes: A Crosslinking Approach Employing Bifunctional Activity‐Based Probes
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Kimberly Cornish Carmony Dr. Lalit Kumar Sharma Do‐Min Lee Ji Eun Park Dr. Wooin Lee Dr. Kyung‐Bo Kim 《Chembiochem : a European journal of chemical biology》2015,16(2):284-292
In addition to two well‐recognized proteasome subtypes—constitutive proteasomes and immunoproteasomes—mounting evidence also suggests the existence of intermediate proteasome subtypes containing unconventional mixtures of catalytic subunits. Although they appear to play unique biological roles, the lack of practical methods for detecting distinct proteasome subtypes has limited functional investigations. Here, we report the development of activity‐based probes that crosslink two catalytic subunits within intact proteasome complexes. Identification of the crosslinked subunit pairs provides direct evidence of the catalytic subunit composition of proteasomes. Using these probes, we found that U266 multiple myeloma cells contain intermediate proteasomes comprising both β1i and β2, but not β1 and β2i, consistent with previous findings with other cell types. Our bifunctional probes can be utilized in functional investigations of distinct proteasome subtypes in various biological settings. 相似文献
993.
Swapan Kumar Ghosh Rajib Bhattacharyya Murari Mohan Mondal Tapobrata Sanyal 《Journal of Natural Fibers》2015,12(5):457-480
In the last quarter of the twentieth century, a new class of materials, Geosynthetics, emerged prospectively leading significant innovation in the design of geotechnical and geoenvironmental systems. Geotextiles have proven to be among the most versatile and techno-economically viable ground modification materials playing a significant role in modern pavement design and maintenance techniques. With the growing environmental concern across the globe, technologists, researchers have inclined towards the natural geotextile where Jute Geotextile (JGT) is one of the potential candidates. But, JGT has been restricted mainly as underlay in road construction. Hence, there is an urgent need to design and develop a precise innovative fabric as overlay on existing pavements and other emerging civil works to stay technically and economically competitive in the global market. Such a fabric will not only prove techno-economically viable but will also reduce the carbon foot-print generation to a large extent. This paper delineates the development of Grey Jute Paving Fabric (GJPF) followed by its bituminization with suitable type and grade of bitumen to develop Bituminized Jute Paving Fabric (BJPF). The BJPF will enhance the life of the overlay thereby reducing the cost of maintenance as well as serving as a partial substitute of bitumen mastic. 相似文献
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Neural Computing and Applications - Heart diseases are of notable public health disquiet worldwide. Heart patients are growing speedily owing to deficient health awareness and bad consumption... 相似文献
996.
Devinder Priyadarshi Rajesh Kumar Sharma 《Journal of Mechanical Science and Technology》2016,30(3):1095-1101
Aluminium matrix composites (AMCs) now hold a significant share of raw materials in many applications. It is of prime importance to study the machinability of such composites so as to enhance their applicability. Sufficient work has been done for studying the machining of AMCs with particle reinforcements of micron range. This paper presents the study of AMCs with particle reinforcement of under micron range i.e. nanoparticles. This paper brings out the results of an experimental investigation of type and weight percent of nanoparticles on the tangential cutting force during turning operation. SiC, Gr and SiC-Gr (in equal proportions) were used with Al-6061 alloy as the matrix phase. The results indicate that composites with SiC require greater cutting force followed by hybrid and then Gr. Increase in the weight percent also significantly affected the magnitude of cutting force. RSM was used first to design and analyze the experiments and then to optimize the turning process and obtain optimal conditions of weight and type of reinforcements for turning operation. 相似文献
997.
Rout Bapin Kumar Brooks Geoff Subagyo Rhamdhani M. Akbar Li Zushu 《Metallurgical and Materials Transactions B》2016,47(6):3350-3361
Metallurgical and Materials Transactions B - Quantification of metal droplets ejected due to impinging gas jet on the surface of liquid metal is an important parameter for the understanding and for... 相似文献
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Multimedia Tools and Applications - The development of the medical services framework is advanced by the development of the Internet of Things (IoT) innovation. There are many hindrances in the... 相似文献