Topology optimization of structures with integral compliant mechanisms for mid-frequency response

The purpose of this paper is to present a method for developing new truss-like sandwich structures that exhibit desirable mid-frequency vibratory characteristics. Specifically, a genetic algorithm optimization routine is used to determine candidate small scale structural topologies, i.e. unit cells, that may be used in the design of larger scale periodic sandwich structures. This multi-scale procedure is demonstrated starting with several unit cell topology optimization examples. From these examples a specific optimal unit cell is selected for further investigation and integration into a periodic sandwich beam. Computational results indicate that the proposed optimization approach is effective when used to design new structures for reduced mid-frequency vibratory response.     

飞机分布式配电系统总线监控器的设计

对基于MIL-STD-1553B多路传输数据总线先进飞机的分布式配电系统的结构和功能进行了分析,重点论述了总线监控器的功能及应用软件的设计及实现;配电系统的消息数量多而且传输频率高,因此如何实现实时监控消息是软件设计的关键;采用Windows消息驱动机制和多线程概念,并结合实时内存数据库技术,很好地解决了实时问题;总线通信试验表明,系统运行可靠,达到了功能要求,具有很好的监控效果,可用于分布式配电系统中。     

无刷电机驱动器在大型医疗设备上的应用

无刷电机及其驱动器在大型医疗上的设备应用越来越广泛。为了设计更好的医疗设备、造福患者,研发人员需要对驱动器有更深的理解和更好的选型及应用。需要理解无刷电机及驱动器的工作原理,清楚大型医疗设备对无刷电机驱动器的要求和实现方式,如安全性、可靠性、通讯等。在医疗设备开发中,驱动器的应用有多种方案,它们各具特点,包括通用驱动器,板载驱动器、自主研发驱动器。随着技术的发展,无刷电机驱动器在大型医疗设备的应用,出现了新的趋势,如:小型化、一体化、模块化和集成化。     

Semi-Supervised Deep Learning for Multi-Tissue Segmentation from Multi-Contrast MRI

Journal of Signal Processing Systems - Segmentation of thigh tissues (muscle, fat, inter-muscular adipose tissue (IMAT), bone, and bone marrow) from magnetic resonance imaging (MRI) scans is useful...     

基于Ad hoc网络的联合有效用户识别与信道安全编译码方法

Ad hoc网络是一种无中心的自组织网络,由于用户能量受限当信噪比较低时有效用户识别的可靠性和信道安全性下降.该文针对这个问题提出一种联合有效用户识别与信道安全编译码方法.将发送用户的正交地址码与接收用户的伪随机地址码异或产生基于发送用户与接收用户的有效用户识别码.为提高信道安全性以信道安全码作为密钥加密有效用户识别码得到正交随机安全序列.为实现扩频并提高传输效率将发送数据以6 bit信息作为一个符号进行分组,将每个符号与一个正交随机安全序列对应.接收用户采用基于子空间的方法处理接收信号,通过建立判决模型识别有效用户.实验结果表明该方法与已有方法相比,当有效用户识别的漏警概率为10–3时信噪比增益改善1.6 dB.     

Poly(N‐phenylglycine)‐Based Nanoparticles as Highly Effective and Targeted Near‐Infrared Photothermal Therapy/Photodynamic Therapeutic Agents for Malignant Melanoma

Malignant melanoma is a highly aggressive tumor resistant to chemotherapy. Therefore, the development of new highly effective therapeutic agents for the treatment of malignant melanoma is highly desirable. In this study, a new class of polymeric photothermal agents based on poly(N‐phenylglycine) (PNPG) suitable for use in near‐infrared (NIR) phototherapy of malignant melanoma is designed and developed. PNPG is obtained via polymerization of N‐phenylglycine (NPG). Carboxylate functionality of NPG allows building multifunctional systems using covalent bonding. This approach avoids complicated issues typically associated with preparation of polymeric photothermal agents. Moreover, PNPG skeleton exhibits pH‐responsive NIR absorption and an ability to generate reactive oxygen species, which makes its derivatives attractive photothermal therapy (PTT)/photodynamic therapy (PDT) dual‐modal agents with pH‐responsive features. PNPG is modified using hyaluronic acid (HA) and polyethylene glycol diamine (PEG‐diamine) acting as the coupling agent. The resultant HA‐modified PNPG (PNPG‐PEG‐HA) shows negligible cytotoxicity and effectively targets CD44‐overexpressing cancer cells. Furthermore, the results of in vitro and in vivo experiments reveal that PNPG‐PEG‐HA selectively kills B16 cells and suppresses malignant melanoma tumor growth upon exposure to NIR light (808 nm), indicating that PNPG‐PEG‐HA can serve as a very promising nanoplatform for targeted dual‐modality PTT/PDT of melanoma.     

Isolation and characterization of seven quorum quenching bacteria for biofouling control in MBR

Recently, interspecies quorum quenching (QQ) by bacteria has been reported as a novel approach in biofouling control in membrane bioreactor (MBR) for wastewater treatment. In this study, seven QQ bacteria, named RO1 to RO7, were isolated from fouling reverse osmosis (RO) membrane and were encapsulated in the microbial filters for biofouling control in MBR. Results showed that all isolates have extracellular QQ activity, and RO1 to RO6 were characterized as heat-stable enzymatic degradation of N-acyl homoserine lactones (AHLs), while RO7 was mainly pH-dependent. Analysis of the 16S rRNA gene indicated that RO7 was a species of Pseudomonas sp., others belonged to the species of Bacillus, Stenotrophomonas maltophilia and Delftia tsuruhatensis, respectively. Then, the microbial filters encapsulated each isolate were applied in a laboratory-scaled MBR and proved the substantial inhibition effect on membrane biofouling except for RO7, indicating that QQ bacteria employing enzymes to degrade AHLs have great potential in biofouling control in MBR.     

Measurement Uncertainty Budget of the PMV Thermal Comfort Equation

Fanger’s predicted mean vote (PMV) equation is the result of the combined quantitative effects of the air temperature, mean radiant temperature, air velocity, humidity activity level and clothing thermal resistance. PMV is a mathematical model of thermal comfort which was developed by Fanger. The uncertainty budget of the PMV equation was developed according to GUM in this study. An example is given for the uncertainty model of PMV in the exemplification section of the study. Sensitivity coefficients were derived from the PMV equation. Uncertainty budgets can be seen in the tables. A mathematical model of the sensitivity coefficients of \(T_{\mathrm{a}}\), \(h_{\mathrm{c}}\), \(T_{\mathrm{mrt}}\), \(T_{\mathrm{cl}}\), and \(P_{\mathrm{a}}\) is given in this study. And the uncertainty budgets for \(h_{\mathrm{c}}\), \(T_{\mathrm{cl}}\), and \(P_{\mathrm{a}}\) are given in this study.     

功率超声在金属熔体成形中的作用效应及其可视化研究进展

主要介绍功率超声在金属熔体成形领域中的作用,详述了超声在铸造成形、辅助焊接成形中细化晶粒、除气除杂、强化焊缝、减小残余应力、促进界面润湿等方面的应用和作用机理。针对超声空化气泡的高速摄影及金属熔体中晶体生长的同步辐射X射线成像观察的研究进展,提出将高速摄影与同步辐射X射线成像结合起来,通过原位观察方法研究超声波与液态金属媒质的相互作用机理,为进一步促进超声在金属熔体成形中的应用提供理论指导。     

电流密度对微/纳结构电铸成型模芯质量的影响

利用多物理场耦合分析软件COMSOL Multiphysics,模拟微/纳结构电铸过程中阴极表面的电场分布,研究不同电流密度下微/纳结构表面的电场分布及电铸层生长前沿情况。仿真结果表明:采用较低的初始电流密度,可有效改善微/纳结构生长前沿铸层厚度的均匀性。选用纳米光阑和纳米柱阵列2种微/纳结构母板进行电铸实验,将初始电流密度从4A/dm2调至1A/dm2,纳米光阑母板成型最大误差60nm降至±20nm之内。通过合理设置初始电流密度、增强阴极表面溶液流动强度等措施,纳米柱阵列模芯特征直径尺寸误差由6.27%下降至2.49%,有效提高电铸模芯的复制质量。